It is reasonable to perform an additional examination of the cardiovascular system in hemodialysis patients, including the definition of HRV with an active orthostatic test and evaluation of the pulse wave velocity by photoplethysmography to predict the fatal cardiovascular events. 

The article reviews intramyocardial course of coronary arteries with myocardial bridging. This report describes the prevalence, clinical presentation, evaluation, and management of adults with symptomatic myocardial bridges. 

The ability of 12-lead averaged electrocardiography (ECG) versus conventional ECG and echocardiography to determine left ventricular hypertensive changes during treatment of arterial hypertension were compared. Averaged ECG was defined to be effective and to excel conventional ECG and echocardiography in determining minor changes of LVH parameters during short-term medical treatment of arterial hypertension. 

Algorithms of electrocardiography were considered. The suggested algorithms allow to answer the first, most important question asked by outpatient doctor, as fast as possible: «norm or pathology», and, furthermore, basing on the clinical principle of diagnostics, close and comprehensible for the practicing doctor: «symptom — syndrome — nosology», formulate electrocardiological conclusion. 

The article considers approaches to selection of hypotensive therapy for different categories of patients, on the basis of age-, sex-, gender-related (social) characteristics of the patients, as well as the range of risk factors and nosological units in the structure of comorbidity. 

The effectiveness of mesalazine in the treatment of patients with slight and moderate ulcerative colitis was studied. Clinical and laboratory remission was achieved in 30 patients with ulcerative colitis. In 1 patient, the drug was canceled due to nausea and vomiting. After 4 weeks, all patients showed signs of minimal colitis according to the histological examination. 

Number of studies related to safety of biological therapy in women patients with intestinal inflammatory diseases during pregnancy is increasing, but the issue is still unsolved due to ethical difficulty of their conducting. The paper systematizes available modern data on possibility of biological drug application in inflammatory intestinal diseases in the pregnant, the level of risk of their potential effect on the fetus was assessed. 

The problem of lactase insufficiency correction in children was considered, as well as approaches to primary and secondary lactase insufficiency. The guidelines on nutrition for infants, considering the characteristics of feeding were given, as well as for children over one year old and adults. 

Oddi’s sphincter dysfunction may have the nature both structural (organic), and functional connected with mobile activity disorders of the sphincter. According to IV Roman Consensus on functional disorders of digestive system 2016, the term «Oddi’s sphincter dysfunction» is recommended for use instead of the terms «postcholecystectomy syndrome», «biliary dyskinesia», etc. The approaches to treatment of Oddi’s sphincter disorders, without its anatomic changes, were considered. 

The article presents the results of multicenter post-marketing randomized comparative prospective study of the efficacy of butyric acid and inulin in patients with different types of irritable bowel syndrome in the complex therapy.

Bloating is a subjective feeling of excessive gas formation and passage of gasses. It is more common in patients with gastrointestinal disorders. For therapy of disorders involving excessive gas formation, fermentative nutraceutical containing alpha-galactosidase can be applied,. Alpha-galactosidase provides fermentative activity which is absent in human body, and prevents entrance of complex sugars to the large intestine in non-split form. 

Aluminium magnesium hydroxide sulfate 5:10:31:2 (magaldrate) is used as an antiacid which neutralizes excess of hydrochloric acid in the stomach. In joint application with siloxane polymer of simethicon, magaldrate shows minimum of side effects (in particular, does not cause high gassing) against the background of increased cytoprotective effect on the gastric mucous membrane. 

Currently, great attention is paid to immunologic and preventive effects of probiotics. This review considers results of randomized controlled studies of probiotic products in prevention of respiratory infections. 

Use of formulas based on goat’s milk in healthy children of first year of life for artificial feeding can be considered as a complete dietary alternative and worthy competition to traditional mixtures based on cow’s milk. Modern formula of goat’s milk due to the peculiarities of the composition of the source material and used modern technology adaptation of infant formula increases the choice of food for healthy children on artificial and mixed feeding, and keep a position of intermediate products, close to the therapeutic feeding. 

The study covered comparison of microbial composition of urogenital tract of sexual partners of females at reproductive age with recurrent bacterial vaginosis who attended gynecologist at the stage of preconception preparation, as well as assessment of the treatment efficiency using antibacterial and immunomodulating therapy, for the risk of bacterial vaginosis recurrence.