The complex, interdisciplinary approaches to the treatment of family-sexual disharmonies in persons with chronic dermatoses are considered, which allows reducing the duration and severity of symptoms of both skin disease and improving the state of the mental and sexual sphere. 

Cognitive disorders are one of the most important problems of health of elderly patients. Due to absence of effective treatment on the stage of clinical dementia, great attention is paid to non-dementia cognitive disorders: moderate, mild, and subjective ones. 

The article describes modern principles of coital anorgasmia diagnostics in women, principles and strategy of therapeutic and rehabilitation measures. The literature review on this issue was presented. 

In the neurorehabilitation department of the hospital of Ufa Emergency care, there were 98 patients after ischemic stroke were treated. The use of complex multidisciplinary and individualized methods of rehabilitation can significantly increase the effect of rehabilitation activities and improve the quality of life of patients. 

The modern data on pathogenesis of drug polyneuropathies were presented, main etiological factors and therapeutic issues were discussed. The data on prevalence, clinical and neurophysiological features induced by chemotherapy were given. 

Clinical and pathogenic role of undergoing multi-organ insufficiency syndrome (MOIS) in neonatal period in neurological outcome formation in in children was studied. 85 children who underwent MOIS in neonatal period, were examined. In the neonatal period, condition, laboratory indices and these instrumental study methods were daily assessed. 

Approaches to the diagnostics and therapy of atopic dermatitis (AtD) were studied, as well as AtD phenotypes and modern views on pathogenesis of this disease, main principles of complex therapy for children with AtD, including dietary therapy and preparations for systemic and topical AtD therapy. 

Generalization of clinical experience of the treatment of 56 patients with chronic dermatoses (atopic dermatitis, eczema, bullous dermatoses) including with secondary pyoderma was used. In the treatment of this patients, we used a new combined drug, containing topical glucocorticosteroid in combination with an antibiotic, antifungal agent and a component that promotes skin repair. Dynamic clinical observations of patients showed that the use of the new drug, both in monotherapy mode, and in the complex treatment of patients, conducted in outpatient and hospital modes, contributed to regression of pyogenic complications and the achievement of clinical remission of the main skin process, the restoration of the quality of life in the vast number of patients, without the formation of side effects and complications from therapy. 

A clinical case of eczema is presented in a representative of one of the smallest people of the North — the Selkup. The disease is associated with professional activity of the patient — the collection of wild plants. 

The article presents optimized approaches to the diagnostics of Mycosis Fungoides. The clinical and anamnestic signs, allowing to suspect Mycosis Fungoides at the clinical stage of the diagnostics, are presented. An innovative method of non-invasive preliminary diagnostics using reflectance confocal microscopy of the skin is described. A rational scheme of examination of patients with suspected Mycosis Fungoides, using new information technologies for registration and monitoring of patients is proposed. 

Clinical cases of long-lasting urethritis in men are presented, during complex examination of which the only etiological agent revealed low-copy N. gonorrhoeae DNA, by PCR RT. After the obligatory confirmation of N. gonorrhoeae high-copy rRNA, with an alternative method of Nasba, an effective treatment of low-symptom gonococcal infection, the disappearance of the clinical symptoms of urethritis was observed, and N. gonorrhoeae eradication. 

The description of the clinical case of a patient with Acne fulminans, the data from the Literature, and own experience justified recommendations for dermatologists and surgeons to optimize the diagnosis and treatment of the disease were presented. 

One of the most serious diagnostic problems is introduced by psychosomatic diseases. Their revealing and treatment in children was the focus of the workshop of Vein’s readings — the largest annual neurological conference. We asked the speakers a few questions. 

Acute neurological diseases require most intensive efforts of patient rehabilitation. We met Larisa Leonidovna Korsunskaya, the chief neurologist of MZ of the Crimea Republic and discussed features and advantages of the region in terms of medical rehabilitation. 

In order to identify and stratify kidney dysfunction in children in accordance with the concept of chronic kidney disease, 125 patients aged 4–18 years with type 1 diabetes mellitus were examined. The main categories were identified: albuminuria and glomerular filtration rate. A comparative analysis of the calculation of GFR by two methods — using the Schwarz formula and the level of cystatin C in the blood plasma — indicates that the latter is much more informative in children. 

The article analyzes the problem of low patients’ compliance during treatment of Helicobacter pylori infection, current approaches to improve commitment to medical recommendations are discussed. It also presents the results of our own study on effectiveness of the drug containing butyric acid and inulin, in increasing tolerance and commitment to treatment among patients receiving standard eradication therapy.

Enteral cross-ligament (ACL) injury and patellofemoral pain syndrome are important problems of sport medicine. Inflammation plays an important role in pathogenesis of osteoarthritis after sport injuries. The influence of injection therapy with multiagent chondroprotectors on functional state and pain level of sportsmen after the ECL reconstruction was studied. Use of multi-agent chondroprotective therapy in structure of rehabilitation program decreased pain level and improved functional state of patellofemoral joint of sportsmen after the ECL reconstruction. 

The latest data on epidemiology of hepatitis B have been analysed in the review article. The latest version of the classification and data on the clinical and laboratory characteristics of the relevant clinical forms of viral hepatitis B, as well as the chronic hepatitis B patient surveillance, have been presented. The article gives up-to-date results on the effectiveness of vaccinal prevention of viral hepatitis B. 

The proposed review summarizes recent advances in the study of respiratory microbiota, the relationship between the upper respiratory tract microbiome and the lung, and a discussion of the possible mechanisms of influence of the microbiome on asthma and allergies. Identifying not only pathogenic bacteria, but also commensals in the respiratory tract and gastrointestinal tract (Gut- Lung axis) is an innovative approach to finding out their role in the development of inflammation and modulation of the immune response in respiratory allergies. 

The aim was to study the correlation between plasma renin activity level and clinical-laboratory, spirographic symptoms in patients with chronic obstructive pulmonary disease (COPD) and arterial hypertension (AH) in patients with arterial hypertension. The work included 86 patients with combined pathology (COPD + AG) and 69 patients with arterial hypertension. All patients underwent plasma level of plasma renin activity (ARP), clinico-laboratory diagnostics, and external respiration function tests. The study revealed the role of plasma renin activity in the development of clinical, laboratory and spirographic symptoms in patients with a combination of COPD and AH.