Probiotic therapy under acute intestinal infections in children
Abstract
Acute intestinal infections is a significant issue in pediatrics. One of the links of pathogenesis is destabilization of microbiocenosis system, which is associated with the action of intestinal infection agents. In this connection, probiotics become the key link of pathogenic therapy of acute intestinal infections. Prescription of these preparations allows to reduce the period of diarrheal syndrome and probability of severe forms development. Choosing the strategy of probiotic therapy, it is necessary to follow the features of the strains which proved their efficiency under acute intestinal infections.
References
1. Инфекционная заболеваемость в Российской Федерации за январь-октябрь 2017 г. (по данным формы № 1 «Сведения об инфекционных и паразитарных заболеваниях») [Электронный ресурс]. Режим доступа: http://www.rospotrebnadzor.ru/activities/statistical-materials/statictic_details.php?ELEMENT_ID=9284 (дата обращения 10.03.2018).
2. О состоянии санитарно-эпидемиологического благополучия населения в Российской Федерации в 2016 году: Государственный доклад. М.: Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человека, 2017. 220 с.
3. Железнова Л. И. Клинико-лабораторные особенности микроэкологических нарушений слизистой толстой кишки при острых кишечных инфекциях у детей. Автореферат дис. … канд. биол. наук. СПб, 2006. 24 с.
4. Physiol. 2009. Vol. 587, Pt. 17. P. 4159–4167.
5. Sekirov I., Finlay B. B. The role of the intestinal microbiota 1in enteric infection // Шендеров Б. А. Медицинская микробная экология и функциональное питание. Т. 3: Пробиотики и функциональное питание. М.: Грантъ, 2001. 286 с.
6. Allen S. J., Martinez E. G., Gregorio G. V. et al. Probiotics for treating acute infectious diarrhoea // Cochrane Database Syst Rev. 2010; CD003048.
7. Quigley E. M. Gut microbiota and the role of probiotics in therapy // Curr Opin Pharmacol. 2011. Vol. 11, № 6. Р. 593–603.
8. Ohara A. M., Shanahan F. Mechanisms of action of probiotics in intestinal diseases // Sci World J. 2007, 7: 31–46.
9. Whiting C. V., Tunmore D., Bregenholt S. et al. The role of up-regulated serine proteases and matrix metalloproteinases in the pathogenesis of a murine model of colitis // Am. J. Pathol. 2000. Vol. 157 (6). Р. 1927–1935.
10. Mattar A. F., Teitelbaum D. H., Drongowski R. A., Yongyi F., Harmon C. M., Coran A. G. Probiotics up-regulate MUC-2 mucin gene expression in a Caco-2 cell-culture model // Pediatr Surg Int. 2002, Oct; 18 (7): 586–590.
11. Juntunen M., Kirjavainen P. V., Ouwehand A. C., Salminen S. J., Isolauri E. Adherence of probiotic bacteria to human intestinal mucus in healthy infants and during rotavirus infection // Clin Diagn Lab Immunol. 2001, Mar; 8 (2): 293–296.
12. Tacket C., Sztein M., Losonsky G. et al. Humoral, mucosal, and cellular immune responses to oral Norwalk virus-like particles in volunteers // Clin. Immunol. 2003. Vol. 108. № 3. P. 241–247.
13. Van der Waaij D. Evidence of immunoregulation of comporetion of intestinal microflora and itspractica on seguences // Eur. J. Clin. Microbiol. 1988. Vol. 7 (1). P. 101–106.
14. Reid G. Probiotics: definition, scope and mechanisms of action // Best Pract Res Clin Gastroenterol. 2016, Feb; 30 (1): 17–25. DOI: 10.1016/j.bpg.2015.12.001.
15. Плоскирева А. А. Острые кишечные инфекции вирусной этиологии у детей клиника, диагностика и терапия. Автореферат дис. … д.м.н. М., 2016.
16. Hojsak I., Fabiano V., Pop T. L., Goulet O., Zuccotti G. V., ?okugras F. C., Pettoello-Mantovani M., Kolacek S. Guidance on the use of probiotics in clinical practice in children with selected clinical conditions and in specific vulnerable groups // Acta Paediatr. 2018, Jun; 107 (6): 927–937. DOI: 10.1111/apa.14270.
17. Szajewska H., Guarino A., Hojsak I., Indrio F., Kolacek S., Shamir R., Vandenplas Y., Weizman Z. Use of probiotics for management of acute gastroenteritis: a position paper by the ESPGHAN Working Group for Probiotics and Prebiotics // J Pediatr Gastroenterol Nutr. 2014, Apr; 58 (4): 531–539.
18. Lund B., Edlund C. Probiotic Enterococcus faecium strain is a possible recipient of the vanA gene cluster // Clin Infect Dis. 2001; 32: 1384–1385.
19. Yasui H., Kiyoshima J., Ushihama H. Passive protection against rotavirus-induced diarrhea of mouse pups born to and nursed by dams fed Bifidobacterium breve YIT4064 // J Infect Dis. 1995; 172: 403–409.
20. Kang J. Y., Lee D. K., Ha N. J., Shin H. S. Antiviral effects of Lactobacillus ruminis SPM0211 and Bifidobacterium longum SPM1205 and SPM1206 on rotavirus-infected Caco-2 cells and a neonatal mouse model // J Microbiol. 2015, Nov; 53 (11): 796–803. DOI: 10.1007/s12275–015–5302–2. Epub 2015 Oct 28.
21. Lee D. K., Park J. E., Kim M. J., Seo J. G., Lee J. H., Ha N. J. Probiotic bacteria, B. longum and L. acidophilus inhibit infection by rotavirus in vitro and decrease the duration of diarrhea in pediatric patients // Clin Res Hepatol Gastroenterol. 2015, Apr; 39 (2): 237–44. DOI: 10.1016/j.clinre.2014.09.006. Epub 2014 Nov 12. PMID: 25459995.
22. Martins F. S., Silva A. A., Vieira A. T., Barbosa F. H., Arantes R. M., Teixeira M. M., Nicoli J. R. Comparative study of Bifidobacterium animalis, Escherichia coli, Lactobacillus casei and Saccharomyces boulardii probiotic properties // Arch. Microbiol. 2009, 191, 623–630.
23. Collado M. C., Meriluoto J., Salminen S. Role of commercial probiotic strains against human pathogen adhesion to intestinal mucus // Lett. Appl. Microbiol. 2007, 45, 454–460.
24. Kawahara T., Makizaki Y., Oikawa Y., Tanaka Y., Maeda A., Shimakawa M., Komoto S., Moriguchi K., Ohno H., Taniguchi K. Oral administration of Bifidobacterium bifidum G9–1 alleviates rotavirus gastroenteritis through regulation of intestinal homeostasis by inducing mucosal protective factors // PLoS One. 2017, Mar 27; 12 (3): e0173979. DOI: 10.1371/journal.pone.0173979. eCollection 2017.
25. Kim K., Lee G., Thanh H. D., Kim J. H., Konkit M., Yoon S., Park M., Yang. S, Park E., Kim W. Exopolysaccharide from Lactobacillus plantarum LRCC5310 offers protection against rotavirus-induced diarrhea and regulates inflammatory response // J Dairy Sci. 2018, Apr 4. Pii: S0022–0302 (18)30309–6. DOI: 10.3168/jds.2017–14151.
26. Huang Y. F., Liu P. Y., Chen Y. Y., Nong B. R., Huang I. F., Hsieh K. S., Chen K. T. Three-combination probiotics therapy in children with salmonella and rotavirus gastroenteritis // J Clin Gastroenterol. 2014, Jan; 48 (1): 37–42. DOI: 10.1097/MCG.0b013e31828f1c6 e.
27. Foster L. M., Tompkins T. A., Dahl W. J. A comprehensive post-market review of studies on a probiotic product containing Lactobacillus helveticus R0052 and Lactobacillus rhamnosus R0011 // Benef Microbes. 2011, Dec 1; 2 (4): 319–334. DOI: 10.3920/BM2011.0032. Review. PMID: 22146691.
Review
For citations:
Ploskireva A.A. Probiotic therapy under acute intestinal infections in children. Lechaschi Vrach. 2018;(6):20. (In Russ.)
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