Comorbidity as an interdisciplinary problem: prediction capability

There are varieties of combination of diseases in the practice of dermatologist. Comorbidity exacerbates the course of the primary disease. Concomitant diseases have common etiopathogenic mechanisms. Currently, there is a widespread increase in the number of patients infected with the human immunodeficiency virus (HIV). «Disguise» of HIV infection — this is one of the urgent problems of modern medicine. Almost every HIV-positive patient has concomitant diseases. Patients with HIV infection have a high incidence of skin lesions, prone to extensive spread and severe relapse. This requires a correct, modern diagnosis, a multidisciplinary approach, which improves the quality of medical care and avoids the complications of drug therapy and diagnostic errors. The clinical case presented in the article has a practical interest in the case of comorbidity interplay. An analysis of a clinical case indicates the clinical and prognostic significance of comorbidity. The clinical course of the recurrent form of herpes zoster indicated the presence of «immunocompetence» in the patient. Upon further consideration of the development of the skin pathological process, the virusinduced genesis of the development of multiforme exudative erythema is clearly traced. Thus, it was shown that the presence of polymorbidity requires an integrated patient-oriented approach in determining the management tactics of this patient population, which will allow you to choose a priority treatment strategy and have a significant impact on the prognosis of diseases and life. 

1. Tlish M. M., Kuznetsova T. G., Naatyzh ZH. Yu. Polimorbidnost’ v dermatologii: pozdnyaya diagnostika i posledstviya [Polymorbidity in dermatology: late diagnosis and consequences] Lechaschi Vrach Journal. 2019; № 7: pp 76-79.

2. Abragamovich O. O., Fayura O. P., Abragamovich U. O. Komorbidnost’: sovremennyy vzglyad na problemu; klassifikatsiya (soobshcheniye pervoye) [Comorbidity: a modern view of the problem; classification (first message)] L’vovskiy klinicheskiy vestnik. 2015; № 4 (12): pp 56-64.

3. Tlish M. M., Popovskaya Ye. B., Kuznetsova T. G., Sycheva L. N., Naatyzh Zh. Yu. Klinicheskiye proyavleniya polimorbidnosti u bol’nykh vitiligo [Clinical manifestations of polymorbidity in patients with vitiligo] Lechaschi Vrach Journal. 2018; № 4: pp 70-74.

4. Yutskovskiy A. D., Bondar’ G. N., Korniyenko A. N. Kozhnyye porazheniya u VICH-infitsirovannogo rebenka: effektivnost’ antiretrovirusnoy terapii [Skin lesions in an HIV-infected child: the effectiveness of antiretroviral therapy] Klinicheskaya dermatologiya i venerologiya. 2009; 3: pp 32-34.

5. Tlish M. M., Kuznetsova T. G., Naatyzh Zh. Yu. Osobennosti klinicheskogo techeniya psoriaza u bol’nykh khronicheskimi virusnymi gepatitami i VICH-infektsiyey [Features of the clinical course of psoriasis in patients with chronic viral hepatitis and HIV infection.] Saratovskiy nauchnomeditsinskiy zhurnal. 2018; 14 (4): pp 765-769.

6. Pokrovskiy V. V., Yermak T. N., Belyayeva V. V., Yurin O. G. VICH-infektsiya: klinika, diagnostika i lecheniye [HIV infection: clinical, diagnosis and treatment] Pod obshch. red. V. V. Pokrovskogo. 2-ye izd., ispr. i dop. M.: GEOTAR-Med, 2003. p 488.