Nutritional support for comorbid patients with asthenic conditions

Objective. The review provides an analysis of modern domestic and foreign literature on the role of nutritional support in comorbid patients with asthenia. The problem of dietary deficiency of B vitamins is discussed, including as a result of a decrease in their absorption, which can be considered as an etiological factor in the development of neurological disorders and a wide range of pathological conditions, including immune ones, the aggravation of which is observed in different groups of the population, including the elderly.

Results. The growing number of patients with complaints of asthenic manifestations in the symptom complex of their underlying disease cannot but cause alarm, so the authors of the article provide data from scientific studies confirming the general clinical trend – the use of sufficient amounts of B-complex vitamins has a positive effect on physical, mental and energetic results in comorbid patientspatients. Separately, the review presents an analysis of data on the need to include B vitamins in the diet to correct the somatopsychic manifestations of stress both in the long term (impact on worker productivity, reducing the number of days of disability, reducing the level of morbidity and accidents, etc.) and short-term needs. The need for further research into the neurocognitive and physical benefits of not only B-complex supplementation, but also other micronutrients, is particularly emphasized, with overall supporting evidence for the benefits of nutritional support in healthy and at-risk populations in terms of physical, mental and energy outcomes. A detailed analysis of the data in the article revealed the need to consider modern data from experimental and clinical studies, the pathogenetic mechanisms of the development of asthenic phenomena in patients with comorbid pathology, and possible points of application of nutritional support in their correction.

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