Difficulties of differential diagnosis of skin pathology in newborn. Clinical observation
https://doi.org/10.51793/OS.2022.25.9.009
Abstract
The management of newborns and infants suffering from skin diseases requires precise decisions and prompt actions from the doctor, the effectiveness of which largely depends on correct and timely diagnosis. Despite the fact that doctors of various specialties are involved in the treatment of children with skin pathologies, it is not always possible to achieve positive results in terms of reducing the level of the disease and increasing the effectiveness of treatment and preventive care. The number of diagnostic errors is especially high. Raising the level of professional nosological diagnostics is a prerequisite for the development of medical care. The etiology and pathogenesis of skin diseases are extremely diverse and in many cases remain unclear. Localized purulent infections of the skin of infants, as a rule, have a staphylococcal and streptococcal etiology. Differential diagnosis of such a pathology is carried out between scalded skin syndrome, Ritter's exfoliative dermatitis, congenital epidermolysis bullosa, Leiner's desquamative erythroderma, and other blistering dermatoses. Staphylococcal scalded skin syndrome is a disease caused by the action of toxins and characterized by the development of erythema and widespread detachment of the surface layers of the epidermis. Ritter's exfoliative dermatitis is a septic variant of the course of epidemic pemphigus in newborns. The etiological factor is most often Staphylococcus 2nd phage group. Epidermolysis bullosa congenita belongs to the group of orphan non-infectious hereditary skin diseases. Leiner-Mousso desquamative erythroderma is a severe disease that affects exclusively children in the first three months of life. In the development of the disease, the sensitizing effect of pyococcal and yeast infections is important against the background of severe metabolic disorders. The article describes a clinical case of staphylococcal scalded skin syndrome in a patient in the neonatal period. The dynamically changing examination data and the results of additional examinations in dynamics are presented and discussed. The diagnostic search and difficulties in making an accurate diagnosis of skin diseases in newborns, which practitioners face, are shown in detail.
About the Authors
T. I. PozhidaevaРоссия
Tatyana I. Pozhidaeva, Assistant, pediatrician
Department of Pediatrics with a course of pediatric surgical diseases
308015
85 Pobedy str.
admission department No. 1
308036
44 Gubkin str.
Belgorod
E. A. Balakireva
Россия
Elena A. Balakireva, Dr. of Sci. (Med.), Professor, Head of the Department
Department of Pediatrics with a Course of Children's Surgical Diseases
308015
85 Pobedy str.
Belgorod
M. V. Sarycheva
Россия
Marina V. Sarycheva, Assistant
Department of Pediatrics with a course of pediatric surgical diseases
308015
85 Pobedy str.
308036
44 Gubkin str.
Belgorod
E. V. Matvienko
Россия
Elena V. Matvienko, MD, Associate Professor
Department of Pediatrics with a Course in Pediatric Surgical Diseases
308015
85 Pobedy str.
Belgorod
M. А. Т. Lakhlukh
Россия
Mokhammad А. Т. Lakhlukh, PhD student
Department of Pediatrics with a course of pediatric surgical diseases
308015
85 Pobedy str.
Belgorod
A. R. M. Alnazhazhra
Россия
Akhmed RM Alnazhazhra, PhD student of the Department of Pediatrics with a course of pediatric surgical diseases
308015
85 Pobedy str.
Belgorod
I. V. Kizilova
Россия
Irina V. Kizilova, Assistant
Department of Pediatrics with a course of pediatric surgical diseases
308015
85 Pobedy str.
308036
44 Gubkin str.
Belgorod
References
1. Гостев В. В. Антибиотикорезистентность метициллинорезистентных Staphylococcus aureus, циркулирующих в Российской Федерации / В. В. Гостев // Антибиотики и химиотерапия. – 2017. – 9. – 3. [Gostev V. V. Antibiotikoreziste ntnost' meticillinorezistentnyh Staphylococcus aureus, cirkuliruyushchih v Rossijskoj Federacii // Antibiotiki i himioterapiya. 2017; 9: 3.]
2. Карпов И. А. Стафилококковая инфекция: клинические аспекты и перспективы терапии / И. А. Карпов, Е. Ф. Качанко // Медицинские новости. – 2016. – 53. – 56. [Karpov I. A., Kachanko E. F. Stafilokokkovaya infekciya: klinicheskie aspekty i perspektivy terapii // Medicinskie novosti. 2016; 53: 56.]
3. Паршина В. А. Клинические рекомендации по ведению новорожденных с заболеваниями кожи и подкожной клетчатки / В. А. Паршина, Д. О. Иванов. – 2016. – С. 15. [Parshina V. A., Ivanov D. O. Klinicheskie rekomendacii po vedeniyu novorozhdennyh s zabolevaniyami kozhi i podkozhnoj kletchatki. 2016. S. 15.]
4. Скрипкин Ю. К. Руководство по детской дерматовенерологии / Ю. К. Скрипкин, Ф. А. Зверькова. – Л.: Медицина, 2018. [Skripkin Yu. K., Zver'kova F. A. Rukovodstvo po detskoj dermatovenerologii. L.: Medicina, 2018.]
5. Has C., Liu L., Bolling M. C., Charlesworth A. V., Hachem M. E. l., Escámez M. J. et al. Dermatol. 2020; 574: 592.
Review
For citations:
Pozhidaeva T.I., Balakireva E.A., Sarycheva M.V., Matvienko E.V., Lakhlukh M.А., Alnazhazhra A.R., Kizilova I.V. Difficulties of differential diagnosis of skin pathology in newborn. Clinical observation. Lechaschi Vrach. 2022;(9):49-55. (In Russ.) https://doi.org/10.51793/OS.2022.25.9.009
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