Tactics of topical therapy of patients with atopic dermatitis using various dosage forms of topical glucocorticosteroid
https://doi.org/10.26295/OS.2020.47.23.009
Abstract
The results of clinical monitoring of the effectiveness and safety of therapy in adult patients with atopic dermatitis using various dosage forms of methylprednisolone aceponate are presented. The rationality of differentiated prescription of dosage forms of methylprednisolone aceponate in the localization of skin manifestation in the problem areas, on the skin of the torso and limbs, and according to the clinical manifestations is shown. The safety of the drug methylprednisolone aceponate in the treatment of patients with atopic dermatitis, the absence of side effects in the treatment at the specified time was confirmed.
About the Authors
N. V. Kungurov
ГБУ СО УрНИИДВиИ
Russian Federation
Russian Federation
M. M. Kokhan
ГБУ СО УрНИИДВиИ
Russian Federation
Russian Federation
Yu. V. Keniksfest
ГБУ СО УрНИИДВиИ
Russian Federation
Russian Federation
E. I. Stukova
ГБУ СО УрНИИДВиИ
Russian Federation
Russian Federation
N. P. Toropova
ГБУ СО УрНИИДВиИ
Russian Federation
Russian Federation
References
1. Bieber T. Atopic Dermatitis // Ann. Dermatol. 2010; 22 (2): 125-137.
2. Darsow U., Wollenberg A., Simon D., Ta??eb A., Werfel T., Oranje A. Gelmetti C., Svensson A., Deleuran M., Calza M., Giusti F., Ring J. ETFAD?EADV eczema task force 2009 position paper on diagnosis and treatment of atopic dermatitis // JEADV. 2010; 24: 317-328.
3. Голдсмит Л. А., Кац С. И., Джилкрест Б. А. и др. Дерматология Фицпатрика в клинической практике / Пер. с англ. под общ. ред. Потекаева Н. Н., Львова А. Н. Изд. 2-е. Издательство Панфилова, 2015. Т. 1, с. 182-200.
4. Федеральные клинические рекомендации. Дерматовенерология 2015: Болезни кожи. Инфекции, передаваемые половым путем. 5-е изд., перераб. и доп. М.: Деловой экспресс, 2016. 768 с.
5. Wollenberg A., Barbarot S., Bieber T., Christen-Zaech S., Deleuran M. et al. GUIDELINES Consensus-based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part I // JEADV. 2018, 32: 657-682.
6. Calzavara Pinton P., Cristaudo A., Foti C., Canonica G. W., Balato N. et al. Diagnosis and management of moderate to severe adult atopic dermatitis: a Consensus by the italian Society of dermatology and Venereology (SidemaSt), the Italian association of Hospital dermatologists, the Italian Society of allergy, asthma and Clinical immunology (SiaaiC), and the italian Society of allergological, environmental and occupational dermatology (SidaPa) // Giornale italiano di dermatologia e Venereologia. 2018; 153 (2): 133-145.
7. Ilgen Ertam, ?zlem Su, Sibel Alper, Hayriye Saricaoglu, Ayse Serap Karadag et al. The Turkish guideline for the diagnosis and management of atopic dermatitis - 2018 // Turkderm-Turk Arch Dermatol Venereology. 2018; 52: 6-23.
8. Кунгуров Н. В., Кохан М. М., Кениксфест Ю. В., Гришаева Е. В., Кащеева Я. В., Куклин И. А. Оптимизация наружной терапии стероидчувствительных дерматозов // Вестн. дерматол. и венерол. 2007; 4: 45-51.
9. Haria M., Balfour J. A. Methylprednisolone aceponate. A review of its pharmacological properties and therapeutic potential in the topical treatment of eczema // Clin Immunother. 1995; 3: 241-253.
10. Brazzini B., Pimpinelli N. New and established topical corticosteroids in dermatology: clinical pharmacology and therapeutic use // Am J. Clin. Dermatol. 2002; 3: 47-58.
11. Luger T., Loske K., Elsner P. et al. Topical skin therapy with glucocorticosteroids - therapeutic index // J Deutsch Dermatol Ges. 2004; 7: 629-634.
12. Luger T. A. Balancing efficacy and safety in the management of atopic dermatitis: the role of methylprednisolone aceponate // JEADV. 2011; 25: 251-258.
13. Chi C. C., Kirtschig G., Aberer, Gabbud J.-P., Lipozencic J., Karp S. et al. Updated evidence-based (S2e) European Dermatology Forum guideline on topical corticosteroids in pregnancy // JEADV. 2017; 31: 761-773.
14. Torrelo A. Methylprednisolone aceponate for atopic dermatitis // Int J Dermatol. 2017; 56 (6): 691-697.
15. Кохан М. М., Кениксфест Ю. В., Новиков Г. М. Эффективность сочетанного применения наружных средств терапии и увлажнения кожи у больных атопическим дерматитом // Вестн. дерматологии и венерологии. 2007; 4: 55-60.
16. Волкова Е. Н., Ланге Д. А., Родина Ю. А., Тарасова М. В. Метилпреднизолона ацепонат в комплексной терапии хронических дерматозов: анализ тактических ошибок применения // Клиническая дерматология и венерология. 2010; 5: 97-102.
17. Дворянкова Е. В., Корсунская И. М., Сакания Л. Р., Невозинская З. А. К вопросу о рациональном выборе топической терапии при атопическом дерматите // Consilium medicum. Дерматология, 2015; 1: 70-74.
18. Hanifin J. M., Thurston M., Omoto M., Cherill R., Tofte S. J., Graeber M. The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis // EASI Evaluator Group. Exp Dermatol. 2001; 10 (1): 11-18.
Review
For citations:
Kungurov N.V., Kokhan M.M., Keniksfest Yu.V., Stukova E.I., Toropova N.P. Tactics of topical therapy of patients with atopic dermatitis using various dosage forms of topical glucocorticosteroid. Lechaschi Vrach. 2020;(2):58-63. (In Russ.) https://doi.org/10.26295/OS.2020.47.23.009
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