New trends in antithrombotic therapy in vascular neurology
https://doi.org/10.51793/OS.2021.24.7.006
Abstract
In recent years, for the first time in developed economies and high-income countries, a reduction in the incidence of stroke has been achieved. The trend towards a decrease in cardiovascular morbidity in economically developed countries of the world proves the effectiveness of a preventive strategy based on the modification of the main risk factors and the use of modern drugs (antihypertensive, hypolipidemic and antithrombotic). The success of preventive medicine is associated with new medical technologies and new more effective drugs – anticoagulants and antiplatelet agents. Antithrombotic therapy for the prevention of the first or repeated stroke is the most important area of primary and secondary prevention of cardiovascular diseases. The author summarizes and analyzes new trends in antithrombotic therapy in clinical practice. The main changes in the antithrombotic strategy relate to the primary prevention of stroke, management of patients with transient ischemic attacks, and early secondary prevention.
About the Author
E. A. ShirokovRussian Federation
Moscow
References
1. Li L., Scott C. A., Rothwell P. M. Trends in Stroke Incidence in High-Income Countries in the 21st Century Population-Based Study and Systematic Review // Stroke. 2020; 51: 00-00. DOI: 10.1161/STROKEAHA.119.028484.
2. The Publications Committee for the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) Investigators. Low molecular weight heparinoid, ORG 10172 (danaparoid), and outcome after acute ischemic stroke: a randomized controlled trial // JAMA. 1998; 279: 1265-1272.
3. Kleindorfer D. O. et al. 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attac. A Guideline From the American Heart Association/American Stroke Association // Stroke. 2021; 52: 00-00. DOI: 10.1161/STR.0000000000000375.
4. Boitzov S. A., Chuchalin A. G., Arutunov G. P. c coavt. Profilaktika chronocheskich neinfektzionnich zabolevanii. [Prevention of chronic noncommunicable diseases. Recommendations.] Moskva, 2013. 40 s.
5. Insult: sovremennie podchodi diagnostiki, lechenia, profilaktiki: metodicheskie rekomendatzii [Stroke: modern approaches to diagnosis, treatment, prevention: guidelines] pod red. Chasanovoi D. R., Danilova V. I. 2014. 248 s.
6. Berger J. S., Jordan C. O., Lloyd-Jones D., Blumenthal R. S. Screening for cardiovascular risk in asymptomatic patients // J Am Coll Cardiol. 2010; 55 (12): 1169-1177. DOI: 10.1016/j.jacc.2009.09.066.
7. Tuna M. A., Rothwell P. M. Diagnosis of non-consensus transient ischaemic attacks with focal, negative, and non-progressive symptoms: population-based validation by investigation and prognosis // Lancet. 2021; 397 (10277): 902-912. DOI: 10.1016/S0140-6736(20)31961-9.
Review
For citations:
Shirokov E.A. New trends in antithrombotic therapy in vascular neurology. Lechaschi Vrach. 2021;(7):30-33. (In Russ.) https://doi.org/10.51793/OS.2021.24.7.006
JATS XML


















