Assessment of subclinical hypertention-mediated heart damage in young adults with connective tissue dysplasia
https://doi.org/10.51793/OS.2021.24.7.005
Abstract
In order to assess the features of hypertension-mediated heart damage in young adults with hypertension and connective tissue dysplasia (СTD), an echocardiographic examination of 574 people aged 18 to 29 years was performed. It was revealed that young adults with hypertension and CTD have lower levels of the interventricular septum and left ventricle walls thickness, left ventricle mass and its indexes than in hypertensive patients without CTD, and these parameters do not reach the generally recognized upper limit of the norm. This leads to systematic underdiagnosis of hypertension-mediated heart damage, incorrect assessment of the stage of hypertension, and inadequate management for these patients.
About the Authors
M. I. ShupinaРоссия
Omsk
Yu. V. Tereschenko
Россия
Omsk
V. V. Potapov
Россия
Omsk
G. I. Nechaeva
Россия
Omsk
References
1. Williams B., Mancia G., Spiering W. et al. 2018 ESC/ESH Guidelines for themanagement of arterial hypertension. The Task Force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH) // European Heart Journal. 2018; 39: 3021-3104. DOI: 10.1093/eurheartj/ehy339.
2. Piskorz D. Hypertensive Mediated Organ Damage and Hypertension Management. How to Assess Beneficial Effects of Antihypertensive Treatments? // High Blood Press Cardiovasc Prev. 2020; 27 (1): 9-17. DOI: 10.1007/s40292-020-00361-6.
3. Rekomendatsii RKO, odobrennyye nauchno-prakticheskim sovetom Minzdrava RF «Arterial'naya gipertenziya u vzroslykh» [Recommendations of the RCS, approved by the scientific and practical council of the Ministry of Health of the Russian Federation «Arterial hypertension in adults»], 2020. p 136
4. Nadruz W. Myocardial remodeling in hypertension // J Hum Hypertens. 2015; 29: 1-6.
5. Yakovlev V. M., Nechayeva G. I., Martynov A. I. i dr. Displaziya soyedinitel'noy tkani v praktike vrachey pervichnogo zvena zdravookhraneniya. Ruk-vo dlya vrachey. [Dysplasia of connective tissue in the practice of primary care physicians. Manual for doctors.] M.: KST Interforum, 2016. p 520
6. Yakovlev V. M., Yagoda A. V., Gusev S. V. Vizual'no-biofizicheskaya diagnostika asimmetrichnoy gipertrofii miokarda levogo zheludochka pri displazii soyedinitel'noy tkani serdtsa [Visual-biophysical diagnosis of asymmetric hypertrophy of the left ventricular myocardium in dysplasia of the connective tissue of the heart] Meditsinskiy vestnik Severnogo Kavkaza. 2013; 1 (8): 23-26
7. Shupina M. I., Nechayeva G. I., Loginova Ye. N., Dorokhov G. Yu. Rasprostranennost' arterial'noy gipertenzii i faktorov serdechno-sosudistogo riska u lits molodogo vozrasta s displaziyey soyedinitel'noy tkani [Prevalence of arterial hypertension and cardiovascular risk factors in young people with connective tissue dysplasia.] The Lechaschi Vrach Journal. 2016; 2: 1-3.
8. Martynov A. I., Nechayeva G. I., Akatova Ye. V. i dr. Klinicheskiye rekomendatsii Rossiyskogo nauchnogo meditsinskogo obshchestva terapevtov po diagnostike, lecheniyu i reabilitatsii patsiyentov s displaziyami soyedinitel'noy tkani (pervyy peresmotr) [Clinical guidelines of the Russian Scientific Medical Society of Physicians for the diagnosis, treatment and rehabilitation of patients with connective tissue dysplasia (first revision)] Meditsinskiy vestnik Severnogo Kavkaza. 2018; 1-2 (13): 137-209.
9. O'Brien E., Petrie J., Littler W. et al. The British Hypertension Society protocol for the evaluation of automated and semi-automated blood pressure measuring devices with special reference to ambulatory systems // J Hypertens. 1990; 8: 607-619.
10. Rekomendatsii po kolichestvennoy otsenke struktury i funktsii kamer serdtsa [Recommendations for the quantitative assessment of the structure and function of the heart chambers] Rossiyskiy kardiologicheskiy zhurnal. 2012; 3 (95, pril. 1): 1-28.
11. Lang R. M., Badano L. P., Mor-Avi V. et al. Recommendations for cardiac chamber quantification by echocardiography in adults: An update from the American society of echocardiography and the European association of cardiovascular imaging // Eur Heart J Cardiovasc Imaging. 2015; 16: 233-271. DOI: 10.1016/j.jacc.2011.07.022.
12. Yildiz M., Oktay A. A., Stewart M. H. et al. Left ventricular hypertrophy and hypertension // Progress in Cardiovasular Diseases. 2020; 63: 10-21. DOI 10.1016/j.pcad.2019.11.009.
13. Gaasch W. H., Zile M. R. Left Ventricular Structural Remodeling in Health and Disease With Special Emphasis on Volume, Mass, and Geometry // J Am Coll Cardiol. 2011; 17 (58): 1733-1740.
Review
For citations:
Shupina M.I., Tereschenko Yu.V., Potapov V.V., Nechaeva G.I. Assessment of subclinical hypertention-mediated heart damage in young adults with connective tissue dysplasia. Lechaschi Vrach. 2021;(7):24-29. (In Russ.) https://doi.org/10.51793/OS.2021.24.7.005
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