The use of specialized products of children’s dietary medical nutrition for children with organic aciduria (acidemia)
https://doi.org/10.51793/OS.2021.24.3.007
Abstract
To assess the efficacy, safety and tolerability of the products specialized children's dietary nutritional therapy in children with Inherited disorders of amino acid metabolism from birth to three years. 8 children from birth to 2y 11m with verified diagnoses were enrolled in this open-label multicenter prospective non-controlled study. Patients were separated to the groups depending on diagnose and nutritional treatment products. Clinical efficacy of the products was assessed according to the Good Clinical Practice guidelines based on clinical and laboratory tests. All patients taken nutritional treatment products throughout the study. No dyspepsia, allergic reactions, impairment of somatic and neurological status were reported. After the treatment, levels of neurotoxic metabolites in the blood and urine were optimal. Nutritional therapy is highly effective in children with Inherited disorders of amino acid metabolism from birth to three years.
About the Authors
N. A. Semenova
Federal State Budgetary Institution Research Centre for Medical Genetics
Россия
Россия
Moscow
E. A. Shestopalova
Federal State Budgetary Institution Research Centre for Medical Genetics
Россия
Россия
Moscow
L. V. Lyazina
St. Petersburg State Public Health Institution «Diagnostic Center (medico-genetic)»
Россия
Россия
St. Petersburg
S. I. Kutsev
Federal State Budgetary Institution Research Centre for Medical Genetics
Россия
Россия
Moscow
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Review
For citations:
Semenova N.A., Shestopalova E.A., Lyazina L.V., Kutsev S.I. The use of specialized products of children’s dietary medical nutrition for children with organic aciduria (acidemia). Lechaschi Vrach. 2021;(3):35-40. (In Russ.) https://doi.org/10.51793/OS.2021.24.3.007
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