Side effects of fluoroquinolone antibiotics: dysglycemia and psychical disorders
Abstract
The article deals with the results of foreign studies and data from the Russian pharmacovigilance database of spontaneous reports that characterize side effects of all fluoroquinolone antibiotics for systemic use — dysglycemia and psychical disorders.
About the Authors
A. V. Kuzmina
ЦМЭБРИЛС ФГБУ ИМЦЭУАОСМП Росздравнадзора
Russian Federation
Russian Federation
A. R. Titova
ЦМЭБРИЛС ФГБУ ИМЦЭУАОСМП Росздравнадзора
Russian Federation
Russian Federation
T. S. Polikarpova
ЦМЭБРИЛС ФГБУ ИМЦЭУАОСМП Росздравнадзора
Russian Federation
Russian Federation
I. L. Asetskaya
Russian Federation
V. A. Polivanov
Russian Federation
References
1. Information for Healthcare Professionals: Fluoroquinolone Antimicrobial Drugs [ciprofloxacin (marketed as Cipro and generic ciprofloxacin), ciprofloxacin extended-release (marketed as Cipro XR and Proquin XR), gemifloxacin (marketed as Factive), levofloxacin (marketed as Levaquin), moxifloxacin (marketed as Avelox), norfloxacin (marketed as Noroxin), and ofloxacin (marketed as Floxin)] URL: http://wayback.archive-it.org/7993/20161022101528/ http:/www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm126085.htm Accessed 12 Jul 2018.
2. FDA Drug Safety Communication: FDA requires label changes to warn of risk for possibly permanent nerve damage from antibacterial fluoroquinolone drugs taken by mouth or by injection URL: http://wayback.archive-it.org/7993/20161022101530/http:/www.fda.gov/Drugs/DrugSafety/ucm365050.htm Accessed 12 Jul 2018.
3. EMA to review persistence of side effects known to occur with quinolone and fluoroquinolone antibiotics URL: http://www.ema.europa.eu/ema/index.jsp? curl=pages/medicines/human/referrals/Quinolones_and_fluoroquinolones_containing_medicinal_products/human_referral_prac_000065.jsp&mid=WC0b01ac05805c516f Accessed 12 Jul 2018.
4. FDA Drug Safety Communication: FDA advises restricting fluoroquinolone antibiotic use for certain uncomplicated infections; warns about disabling side effects that can occur together URL: https://www.fda.gov/Drugs/DrugSafety/ucm500143.htm Accessed 12 Jul 2018.
5. FDA Drug Safety Communication: FDA updates warnings for oral and injectable fluoroquinolone antibiotics due to disabling side effects URL: https://www.fda.gov/Drugs/DrugSafety/ucm511530.htm Accessed 12 Jul 2018.
6. FDA reinforces safety information about serious low blood sugar levels and mental health side effects with fluoroquinolone antibiotics; requires label changes URL: https://www.fda.gov/Drugs/DrugSafety/ucm611032.htm Accessed 12 Jul 2018.
7. Aspinall S.L., Good C. B., Jiang R. et al. Severe Dysglycemia with the Fluoroquinolones: A Class Effect? // Clin Infect Dis. 2009; 49 (3): 402–408.
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10. Doussau de Bazignan A., Thiessard F., Miremont-Salam? G. et al. Psychiatric adverse effects of fluoroquinolone: review of cases from the French pharmacologic surveillance database // Rev Med Interne. 2006, Jun; 27 (6): 448–452.
Review
For citations:
Kuzmina A.V., Titova A.R., Polikarpova T.S., Asetskaya I.L., Polivanov V.A. Side effects of fluoroquinolone antibiotics: dysglycemia and psychical disorders. Lechaschi Vrach. 2018;(10):87. (In Russ.)
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