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Lechaschi Vrach

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The role of the respiratory tract microbiome in respiratory health

Abstract

The proposed review summarizes recent advances in the study of respiratory microbiota, the relationship between the upper respiratory tract microbiome and the lung, and a discussion of the possible mechanisms of influence of the microbiome on asthma and allergies. Identifying not only pathogenic bacteria, but also commensals in the respiratory tract and gastrointestinal tract (Gut- Lung axis) is an innovative approach to finding out their role in the development of inflammation and modulation of the immune response in respiratory allergies. 

About the Authors

N. G. Astafieva
ФГБОУ ВО СГМУ им. В. И. Разумовского МЗ РФ
Russian Federation


D. Yu. Kobzev
Лидс Тринити университет
Russian Federation


I. V. Gamova
ФГБОУ ВО СГМУ им. В. И. Разумовского МЗ РФ
Russian Federation


I. A. Perfilova
ФГБОУ ВО СГМУ им. В. И. Разумовского МЗ РФ
Russian Federation


E. N. Udovichenko
ФГБОУ ВО СГМУ им. В. И. Разумовского МЗ РФ
Russian Federation


L. V. Skuchaeva
ФГБОУ ВО СГМУ им. В. И. Разумовского МЗ РФ
Russian Federation


I. E. Michailova
ФГБОУ ВО СГМУ им. В. И. Разумовского МЗ РФ
Russian Federation


Review

For citations:


Astafieva N.G., Kobzev D.Yu., Gamova I.V., Perfilova I.A., Udovichenko E.N., Skuchaeva L.V., Michailova I.E. The role of the respiratory tract microbiome in respiratory health. Lechaschi Vrach. 2019;(4):12. (In Russ.)

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ISSN 1560-5175 (Print)
ISSN 2687-1181 (Online)