The effectiveness of chondroprotective therapy in patients with lumbosacral dorsopathies
https://doi.org/10.26295/OS.2020.63.60.012
Abstract
A study of the effectiveness and safety of the chondroprotector in patients suffering from lumbosacral dorsopathy. The study included 30 patients aged 40 to 60 years, suffering from lumbosacral dorsopathy with radiculoishemia and not requiring surgical treatment. Analysis of the results showed that chondroprotector is effective in lumbosacral dorsopathy at the prescribed dose: its use reduces the severity of symptoms by more than 50% from the initial level in 83.3% of patients, reduces the intensity of pain in 90%, eliminates the neuropathic component of pain in 73.3%, and significantly improves the quality of life by more than 10 points for each indicator of the SF-36 questionnaire in 76.7%. Chondroprotector showed a high safety profile; all patients demonstrated high compliance and completed the study in according to the plan. Thus, chondroprotector can be recommended in the treatment of lumbosacral dorsopathy with radiculoischemia.
About the Authors
N. V. Yakovleva
Rostov State Medical University
Россия
Россия
Rostov-na-Donu
G. V. Shavkuta
Rostov State Medical University
Россия
Россия
Rostov-na-Donu
T. V. Shnyukova
Rostov State Medical University
Россия
Россия
Rostov-na-Donu
References
1. Khronicheskaya bol' v spine: klinicheskiye rekomendatsii. [Chronic back pain: clinical guidelines.] Elektronnyy resurs. Rezhim dostupa: URL: http://www.roszdravnadzor.ru/i/upload/images/2015/9/17/1442492612.6616-1-5131.doc.
2. Yakhno N. N., Kukushkin M. L. Khronicheskaya bol': mediko-biologicheskiye i sotsial'no-ekonomicheskiye aspekty [Chronic pain: medico-biological and socio-economic aspects] Vestnik Rossiyskoy akademii meditsinskikh nauk. 2012. № 9. S. 54-58.
3. Norasteh Ali Asghar. Low Back Pain / Edited by Ali Asghar Norasteh. ISBN 13: 9789535105992, In Tech. 2012. 361 pp.
4. Bergström G., Hagberg J., Busch H. et al. Prediction of Sickness Absenteeism, Disability Pension and Sickness Presenteeism Among Employees with Back Pain // J Occup Rehabil. 2014. Vol. 24, № 2. P. 278-286.
5. Osteokhondroz pozvonochnika: klinicheskiye rekomendatsii. [Spinal osteochondrosis: clinical guidelines.] Elektronnyy resurs. Rezhim dostupa: URL: http://kokb45.ru/wp-content/uploads/2018/06/Osteohondroz-pozvonochnika.pdf.
6. Kosarev V. V., Babanov S. A. Khronicheskaya poyasnichno-kresttsovaya radikulopatiya: sovremennoye ponimaniye i osobennosti farmakoterapii [Chronic lumbosacral radiculopathy: modern understanding and features of pharmacotherapy] Russkiy meditsinskiy zhurnal. 2013. T. 21. № 16. Pp. 844-851.
7. Yakovleva N. V., Gorblyanskiy Yu. Yu., Piktushanskaya T. Ye. i dr. Professional'naya poyasnichno-kresttsovaya radikulopatiya: uchebnoye posobiye [Professional lumbosacral radiculopathy: a tutorial] Pod red. Yu. Yu. Gorblyanskogo. FGBOU VO Rostgmu Minzdrava Rossii, GBU RO «LRTS № 2». Rostov-na-Donu: Izd-vo Fond nauki i obrazovaniya, 2016. 96 p.
8. Levin O. S. Vertebrogennaya poyasnichno-kresttsovaya radikulopatiya: sovremennyye podkhody k diagnostike i lecheniyu [Vertebral lumbosacral radiculopathy: modern approaches to diagnosis and treatment] Effektivnaya farmakoterapiya. 2015. № 23. Pp. 40-49.
9. Barulin A. Ye., Kurushina O. V. Khondroprotektory v kompleksnoy terapii boley v spine [Chondroprotectors in the complex therapy of back pain] RMJ. 2013. T. 21, № 30. Pp. 1543-1545.
10. Zhang W., Nuki G., Moskowitz R. W. et al. OARSI recommendations for the management of hip and knee Osteoarthritis // Osteoarthritis Cartilage. 2010. Vol. 18. P. 476-499.
11. Nikolayeva S. S., Kim Z. Ch., Bykov V. A. i dr. Vlagoobmennyye protsessy v gialinovom khryashche i yego osnovnykh komponentakh v norme i osteoartroze [Moisture exchange processes in hyaline cartilage and its main components in normal vitals and osteoarthritis] Voprosy meditsinskoy khimii. 2000. T. 46, № 6. Pp. 581-590.
12. Bouhassira D., Attala N., Alchaar H. et al. Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4) // Pain. 2005. № 114. Р. 29-36.
13. Ware J. E. Jr., Sherbourne C. D. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection // Med Care. 1992. Vol. 30, № 6. P. 473-83.
14. Yakovleva N. V. Otsenka psikhoemotsional'nogo sostoyaniya i kachestva zhizni bol'nykh professional'noy poyasnichno-kresttsovoy radikulopatiyey v postkontaktnom periode [Assessment of the psychoemotional state and quality of life of patients with occupational lumbosacral radiculopathy in the post-exposure period] Meditsina truda i promyshlennaya ekologiya. 2015. № 9. Pp. 162.
Review
For citations:
Yakovleva N.V., Shavkuta G.V., Shnyukova T.V. The effectiveness of chondroprotective therapy in patients with lumbosacral dorsopathies. Lechaschi Vrach. 2020;(12):61-65. (In Russ.) https://doi.org/10.26295/OS.2020.63.60.012
Views:
245
JATS XML
Email this article 
