Pregnancy complicated by cervical cancer: modern treatment approaches in the russian literature

Abstract

Background. Cervical cancer is one of the most common forms of malignant tumors diagnosed in women of reproductive age, including during pregnancy. Due to the relative rarity of this disease in combination with pregnancy and the limited number of randomized clinical trials, the development of standardized treatment algorithms presents significant challenges. Therapeutic approaches to cervical cancer during pregnancy are extrapolated from guidelines developed for non-pregnant patients, relying heavily on expert consensus and limited clinical evidence. The lack of large-scale studies in this specific clinical context necessitates a tailored approach for each patient, based on the stage of the disease, gestational age, and overall health.
Results. To compile this review, a search of the electronic libraries eLibrary.ru and PubMed was conducted using the keywords "pregnancy" and "cervical cancer". For treatment descriptions, primarily Russian articles published within the five years prior to the article were selected. Management strategies for pregnancy associated with cervical cancer remain an area of active debate in the scientific community. For pregnant women who insist on continuing their pregnancy, specialized therapy may be administered based on the stage of cervical cancer, tumor size, gestational age, fetal condition, and the extent of pelvic lymph node involvement.
Conclusion. Analysis of domestic clinical data over the past five years demonstrates the use of a personalized approach to treating cervical cancer in pregnant women. Treatment strategies are determined by a panel of specialists from various fields and are based on shared decision-making with the patient. This approach takes into account all the nuances of the clinical picture and the patient's individual preferences, helping to optimize treatment outcomes and preserve reproductive function.