Метотрексат в лечении ревматоидного артрита и псориатического артрита
Аннотация
Об авторах
Н. В. Чичасова
ФГБНУ НИИР им. В. А. Насоновой; ФГБОУ ДПО РМАНПО Минздрава России
Россия
Россия
доктор медицинских наук, профессор,
Москва
А. М. Лила
ФГБНУ НИИР им. В. А. Насоновой; ФГБОУ ДПО РМАНПО Минздрава России
Россия
Россия
доктор медицинских наук, профессор,
Москва
Список литературы
1. Российские клинические рекомендации. Ревматология / Под ред. академика РАН Е. Л. Насонова. М.: ГЕОТАР-Медиа, 2020, с. 17–57. URL: http://www.geotar.ru.
2. Ogdie A., Weiss P. The epidemiology psoriatic arthritis // Rheum Dis Clin North Am. 2015; 41 (4): 545–568. DOI: 10.106/j.rdc.2015.07.001.
3. Галушко Е. А., Насонов Е. Л. Распространенность ревматических заболеваний в России // Альманах клинической медицины. 2018; 46 (1): 32–33. DOI: 10.18786/2072-0505-2018-46-1-32-39.
4. Jadrapai A., Navarro-Millan I. Cardiovascular co-morbidity in patients with rheumatoid arthritis: a narrative review of risk factors, cardiovascular risk assessment and treatment // BMC Rheumatology. 2018, 2: 10. DOI: 10.1186/s41927-018-0014-y.
5. DeMizio D. J., Geraldino-Pardilla L. B. Autoimmunity and inflammation link to cardiovascular disease risk in rheumatoid arthritis // Rheumatol Ther. 2020; 7 (1): 19–33. DOI: 10.1007/s40744-019-00189-0.
6. Labitigan M., Bahče-Altuntas A., Kremer J. M., et al. Higher rates and clustering of abnormal lipids, obesity, and diabetes mellitus in psoriatic arthritis compared with rheumatoid arthritis // Arthritis Care Res (Hoboken). 2014; 66 (4): 600–607. DOI: 10.1002/acr.22185.
7. Johnsson H., McInnes I. B., Sattar N. Cardiovascular and metabolic risks in psoriasis and psoriatic arthritis: pragmatic clinical management based on available evidence // Ann Rheum Dis. 2012; 71 (4): 480–483. DOI: 10.1136/annrheumdis-2011-200567.
8. Coto-Segura P., Eiris-Salvado N., Gonzalez-Lara L., et al. Psoriasis, psoriatic arthritis and type 2 diabetes mellitus: a systematic review and meta-analysis // Br J Dermatol. 2013; 169 (4): 783–793. DOI: 10.1111/bjd.12473.
9. Bhole V. M., Choi H. K., Burns L. C., et al. Differences in body mass index among individuals with PsA, psoriasis, RA and the general population // Rheumatology (Oxford). 2012; 51 (3): 552–556. DOI: 10.1093/rheumatology/ker349.
10. Jamnitski A., Symmons D., Peters M. J. L., Sattar N., McInnes I., Nurmohamed M. T. Cardiovascular comorbidities in patients with psoriatic arthritis: a systematic review // Ann Rheum Dis. 2013; 72 (2): 211–216. DOI: 10.1136/annrheumdis-2011-201199.
11. Smolen J. S., Aletaha D., Bijlsma J. W., et.al. Treating rheumatoid arthritis to target: recommendations of an international task force // Ann Rheum Dis. 2010: 69: 631–637.
12. Smolen J. S., Landewe R. B. M., Bijlsma W. J., et. al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update // Ann Rheum Dis. 2020; 79 (6): 685–699. DOI:10.1136/annrheumdis-2019-216655.
13. Lard L. R.., Visser H.., Speyer I. et al. Early versus delayed treatment in patients with recent-onset rheumatoid arthritis: comparison of two cohorts who received different treatment strategies // Amer. J. Med. 2001; 111: 446-451. DOI: 10.1016/s0002-9343(01)00872-5.
14. Pincus T., Yazici Y., Sokka T., et al. Methotrexate as the “anchor drug” for the treatment of early rheumatoid arthritis // Clin Exp Rheumatol. 2003; 21 (Suppl 31): S178–85. https://www.clinexprheumatol.org/article.asp?a=2212.
15. Насонов Е. Л.., Каратеев Д. Е., Чичасова Н. В. Новые рекомендации по лечению ревматоидного артрита (EULAR, 2013): место метотрексата // Научно-практ. ревматология. 2014, 52 (1): 8-26. DOI: 10.14412/1995-4484-2014-8-26.
16. Aletaha D., Funovits J., Smolen J. S. The importance of reporting disease activity states in clinical trials of rheumatoid arthritis // Arthritis Rheum. 2008; 58: 2622–2631. DOI: 10.1002/art.23733.
17. Smolen J. S., Landewé R., Bijlsma J., et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease- modifying antirheumatic drugs: 2016 update // Ann Rheum Dis. 2017; 76: 960–977. DOI: 10.1136/annrheumdis-2016-210715.
18. Shea B., Swinden M. V., Tanjong Ghogomi E., et al. Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis // Cochrane Database Syst Rev. 20131; 5: CD000951. DOI: 1002/14651858.CD000951.pub2.
19. Hoekstra M., Haagsma C., Neef C., et al. Bioavailability of high dose methotrexate comparing oral and subcutaneous administration in patients with rheumatoid arthritis // J Rheumatol. 2004; 31 (4): 645–648.
20. Schiff M. H., Jaffe J. S., Freundlich B. Head-to-head, randomised, crossover study of oral versus subcutaneous methotrexate in patients with rheumatoid arthritis: drug-exposure limitations of oral methotrexate at doses ≥15 mg may be overcome with subcutaneous administration // Ann Rheum Dis. 2014; 73 (8): 1549–1551. DOI: 10.1136/annrheumdis-2014-205228.
21. Desmoulin S. K., Hou Z., Candjee A., Matherly L. H. The human proton-coupled folate transporter: biology and therapeutic applications to cancer // Cancer Biol Ther. 2012; 13: 1355-1373. DOI: 10.4161/cbt.22020.
22. Hillson J. L., Furst D. E. Pharmacology and pharmacokinetics of methotrexate in rheumatic disease. Practical issues in treatment and design // Rheum. Dis. Clin. N. Am. 1997, 23, 757–778. DOI: 10.1007/s00296-016-3447-x.
23. Hameed B., Jones H. Subcutaneous methotrexate is well tolerated and superior to oral methotrexate in the treatment of rheumatoid arthritis // Int J Rheum Dis. 2010; 13 (4): e83–e84. DOI: 10.1111/j.1756-185X.2010.01482.x.
24. Bianchi G., Caporali R., Todoerti M., Mattana P. Methotrexate and rheumatoid arthritis: current evidence regarding subcutaneous versus oral routes of administration // Adv Ther. 2016; 33 (3): 369–378. DOI: 10.1007/s12325-016-0295-8.
25. Branco J. C., Barcelos A., de Araújo F. P., et al. Utilization of subcutaneous methotrexate in rheumatoid arthritis patients after failure or intolerance to oral methotrexate: a Multicenter Cohort Study // Adv Ther. 2016; 33 (1): 46–57. DOI: 10.1007/s12325-016-0295-8.
26. Braun J., Kastner P., Flaxenberg P., et al. Comparison of the clinical efficacy and safety of subcutaneous versus oral administration of methotrexate in patients with active rheumatoid arthritis: results of a six-month, multicenter, randomized, double-blind, controlled, phase IV trial // Arthritis Rheum. 2008; 58 (1): 73–81. DOI: 10.1002/art.23144.
27. Harris E., Ng B. Using subcutaneous methotrexate to prolong duration of methotrexate therapy in rheumatoid arthritis // Eur J Rheumatol. 2018; 5: 85–91. DOI: 10.5152/eurjrheum.2018.17113.
28. Yadlapati S., Efthimiou P. Inadequate Response or Intolerability to Oral Methotrexate: Is It Optimal to Switch to Subcutaneous Methotrexate Prior to Considering Therapy With Biologics? // Rheumatol Int. 2016; 36 (5): 627–633. DOI: 10.1007/s00296-016-3447-x.
29. Scott D. G., Claydon P., Ellis C. Retrospective evaluation of continuation rates following a switch to subcutaneous methotrexate in rheumatoid arthritis patients failing to respond to or tolerate oral methotrexate: the MENTOR study // Scand J Rheumatol. 2014; 43 (6): 470–476. DOI: 10.1111/j.1756-185X.2010.01482.x.
30. Bujor A. M., Janjua S., LaValley M. P., Duran J., Braun J., Felson D. T. Comparison of oral versus parenteral methotrexate in the treatment of rheumatoid arthritis: A meta-analysis // PLoS ONE. 14 (9): e0221823. https://DOI.org/10.1371/journal.pone.0221823.
31. Muller R. B., von Kempis J., Haile S. R., Schiff M. H. Effectiveness, tolerability, and safety of subcutaneous methotrexate in early rheumatoid arthritis: a retrospective analysis of real-world data from the St. Gallen cohort // Semin Arthritis Rheum. 2015; 45 (1): 28–34. DOI: 10.1016/j.semarthrit.2015.02.009.
32. Чичасова Н. В. Возможности достижения максимального эффекта при контролируемом лечении ревматоидного артрита в реальной практике // Лечащий Врач. 2015, № 7: 29–33. URL: https://www.lvrach.ru-2015/07.
33. Каратеев Д. Е., Лучихина Е. Л., Демидова Н. В. и др. Применение подкожной формы метотрексата для лечения больных активным ревматоидным артритом (исследование РЕМАРКА) // Научно-практ. ревматология. 2016; 54 (2): 138–144. http://dx.DOI.org/10.14412/1995-4484-2016-138-144.
34. Agenova S., Steenberg H. W., van Nies J. A. B., et al. Disease-modifying antirheumatic drug-free sustained remission in rheumatoid arthritis: an increasingly achievable outcome with subsidence of disease symptoms // Ann Rheum Dis. 2016; 75 (5): 867–73. DOI: 10.1136/annrheumdis-2014-207080.
35. Burgers L. E., Huizingal T. W. J., Allaart C. F., van der Helm-van Mill A. H. M. Does treatment strategy influence the ability to achieve and sustain DMARDfree remission in patients with RA? Results of an observational study comparing an intensified DAS-steered treatment strategy with treat to target in routine care // Arthritis Research & Therapy. 2019; 21: 115. https:// DOI.org/10.1186/s13075-019-1893-z.
36. Salliot C., van der Heijde D. Long-term safety of methotrexate monotherapy in patients with rheumatoid arthritis: a systematic literature research // Ann Rheum Dis. 2009; 68 (7): 1100–1104. DOI: 10.1136/ard.2008.093690.
37. Curtis J. R., Beukelman T., Onofrei A., et al. Elevated liver enzyme tests among patients with rheumatoid arthritis or psoriatic arthritis treated with methotrexate and/or leflunomide // Ann Rheum Dis. 2010; 69 (1): 43–47. DOI: 10.1136/ard.2008.101378.
38. Sostman H. D., Matthay R. A., Putman C. E., Smith G. J. Methotrexateinduced pneumonitis // Medicine (Baltimor). 1976; 55 (5): 371–388. DOI: 10.1097/00005792-197609000-00002.
39. Whitcomb M. E., Schwarz M. I., Tormey D. C. Methotrexate Pneumonitis: case report and review of the literature // Torax. 1972; 27 (5): 636–639. DOI: 10.1136/thx.27.5.636.
40. Conway R., Low C., Coughlan R. J., et al. Methotrexate and lung disease in rheumatoid arthritis: a meta-analysis of randomized controlled trials // Arthr Rheum. 2014; 66 (4): 803–812. DOI: 10.1002/art.38322.
41. Rojas-Serrano J., Gonzalez-Velasquez E., Mejia M., et al. Interstitial lung disease related to rheumatoid arthritis: evolution after treatment // Rheumatol Clin. 2012; 8 (2): 68–71. DOI: 10.1016/j.reuma.2011.12.008.
42. Jani M., Dixon W. G., Matteson E. L. Management of the rheumatoid arthritis with interstitial lung disease // Lung disease in rheumatoid arthritis. 2018: 121–161. DOI: 10.1007/978-3-319-68888-6_9.
43. Насонов Е. Л. Метотрексат при ревматоидном артрите — 2015: новые факты и идеи // Научно-практ. ревматология. 2015: 53 (5s): 64–76. [Nasonov E. L. Metotreksat pri revmatoidnom artrite — 2015: novye fakty I idei [Methotrexate in rheumatoid arthritis-2015: new facts and ideas] // Nauchno-prakt. revmatologiya. 2015: 53 (5s): 64–76. (In Russ.)] DOI:10.14412/1995-4484-2015-64-76.
44. Gladman D. D., Thavaneswaran A., Chandran V., et al. Do patients with psoriatic arthritis who present early fare better than those presenting later in the disease? // Ann Rheum Dis. 2011; 70 (12): 2152–2154. DOI: 10.1136/ard.2011.1509385.
45. Theander E., Husmark T., Alenius G. M., et al. Early psoriatic arthritis: short symptom duration, male gender and preserved physical functioning at presentation predict favorable outcome at 5-year follow-up. Results from the Swedish Early Psoriatic Arthritis Register (SwePsA) // Ann Rheum Dis. 2014; 73 (2): 407–413. DOI: 10.1136/annrheumdis-2012-201972.
46. Haroon M., Gallagher P., Fitzgerald O. Diagnostic delay of more than 6 months contributes to poor radiographic and functional outcome in psoriatic arthritis // Ann Rheum Dis. 2014; published online Feb 13. DOI: 10.1136/annrheumdis-2013-204858.
47. Gossec L., Baraliakos X., Kerschbaumer A., et al. EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2019 update // Ann Rheum Dis. 2020; 79 (6): 700–712. DOI: 10.1136/annrheumdis-2020-217159.
48. Российские клинические рекомендации. Ревматология / Под ред. акад. РАН Е. Л. Насонова. М.: ГЕОТАР-Медиа, 2020. С. 101–109. URL: http://www.geotar.ru.
49. Coates L. C., Kavanaugh A., Mease P. J., et al. Group for Research and Assessment of Psoriasis and Psoriatic Arthritis 2015 Treatment Recommendations for Psoriatic Arthritis // Arthr Rheumtol. 2016; 68 (5): 1060–1071. DOI: 10.1002/art.39573.
50. Elmamoun M., Eraso M., Anderson M., et al. International league of associations for rheumatology recommendations for the management of psoriatic arthritis in resource-poor settings // Clin Rheumatology. 2020; 39 (6): 1839–1850. https://DOI.org/10.1007/s10067-020-04934-7.
51. Kane D., Gogarty M., O’leary J., et al. Reduction of synovial sublining layer inflammation and proinflammatory cytokine expression in psoriatic arthritis treated with methotrexate // Arthritis Rheum. 2004; 50 (10): 3286–3295. DOI: 10.1002/art.20518.
52. Curran S. A., FitzGerald O. M., Costello P. J., et al. Nucleotide sequencing of psoriatic arthritis tissue before and during methotrexate administration reveals a complex inflammatory T cell infiltrate with very few clones exhibiting features that suggest they drive the inflammatory process by recognizing autoantigens // J Immunol. 2004; 172 (3): 1935–1944. DOI: 10.4049/jimmunol.172.3.1935.
53. Kingsley G. H., Kowalczyk A., Taylor H., et al. A randomized placebo- controlled trial of methotrexate in psoriatic arthritis // Rheumatology. 2012; 51 (8): 1368–1377. DOI: 10.1093/rheumatology/kes001.
54. Lie E., van der Heijde D., Uhlig T., et al. Effectiveness and retention rates of methotrexate in psoriatic arthritis in comparison with methotrexate- treated patients with rheumatoid arthritis // Ann Rheum Dis. 2010; 69 (4): 671–676. DOI: 10.1136/ard.2009.113308.
55. Coates L. C., Moverley A. R., McParland L., et al. Effect of tight control of inflammation in early psoriatic arthritis (TICOPA): a UK multicenter, openlabel, randomised controlled trial // Lancet. 2015; 386 (10012): 2489–2498. DOI: 10.1016/S0140-6736(15)00347-5.
56. Smolen J. S., Schöls M., Braun J., et al. Treating axial spondylarthritis and peripheral spondylarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force // Ann Rheum Dis. 2018; 77 (1): 3–17. DOI: 10.1136/annrheumdis-2017-211734.
57. Логинова E. Ю., Коротаева T. В., Смирнов A. В., Koлтакова A. Д., Насонов Е. Л. Достижение минимальной активности болезни и динамика рентгенологических изменений при раннем псориатическом артрите через год после начала лечения в рамках стратегии «Лечение до достижения цели» (предварительные результаты исследования РЕМАРКА) // Научно-практическая ревматология. 2017; 55 (6): 610–615. DOI: 10.14412/1995-4484-2017-610-615.
58. Coates L. C., Fransen J., Helliwell P. S. Defining minimal activity in psoriatic arthritis: a proposed objective target for treatment // Ann Rheum Dis. 2010; 69 (1): 48–53. DOI: 10.1136/ard.2008.102053.
59. Mease P. J., Gladman D. D., Collier D. H., et al. Etanercept and methotrexate as monotherapy or in combination for psoriatic arthritis: primary results from a randomized, controlled phase III trial // Arthritis Rheumatol. 2019; 71 (7): 1112–24. DOI: 10.1002/art.40851.
60. Curtis J. R., Beukelman T., A Onofrei A., et al. Elevated liver enzyme tests among patients with rheumatoid arthritis or psoriatic arthritis treated with methotrexate and/or leflunomide // Ann Rheum Dis. 2010; 69 (1): 43–47. DOI: 10.1136/ard.2008.101378.
61. Wilson T. D., Whittle S. L., Thynne T. R. J., Mangoni A. A. Methotrexate for psoriatic arthritis // Cochrane Database of Systematic Reviews. 2019, Issue 1. Art. No.: CD012722. DOI: 10.1002/14651858.CD012722.pub2.
62. Roubille C., Richer V., Starnino T., McCourt C. The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis, psoriasis and psoriatic arthritis: a systematic review and meta-analysis // Ann Rheum Dis. 2015; 74 (3): 480–489. DOI: 10.1136/annrheumdis-2014-206624.
63. Westlake S. L., Colebatch A. N., Baird J. et al. The effect of methotrexate on cardiovascular disease in patients with rheumatoid arthritis: a systematic literature review // Rheumatology. 2010; 49 (2): 295–307. DOI: 10.1093/rheumatology/kep366.
64. Visser K., Katcharmart W., Loza E. et al. Multinational evidence-based recommendations for use methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: intergrading systematic literature research and expert opinion of a board international panel of rheumatologists in the 3E initiative // Ann. Rheum. Dis. 2009, 68 (7): 1086–1093. DOI: 10.1136/ard.2008.094474.
65. Pincus T., Ferraccioli G., Sokka T. et al. Evidence of clinical trials and long-term observational studies that disease-modifying anti-rheumatic drugs slow radiographic progression in rheumatoid arthritis: updating 1983 review // Rheumatol. 2002, 41 (12): 1346–1356. DOI: 10.1093/rheumatology/41.12.1346.
66. Rohr M. K., Mikuls T. R., Cohen S. B., Thorne C. J., O’Dell J. R. The underuse of methotrexate in the treatment of RA: a national analysis of prescribing practices in the U.S. Arthritis Care Res (Hoboken) // Arthr Care Res. 2017; 69 (6): 794–800. DOI: 10.1002/acr.23152.
67. Bello A. E., Perkins E. L., Jay R., Efthimiou P. Recommendations for optimizing methotrexate treatment for patients with rheumatoid arthritis // Open Access Rheumatol. 2017; 31 (9): 67–79. DOI: 10.2147/OARRR.S131668.s.
68. Hameed B., Jones H. Subcutaneous methotrexate is well tolerated and superior to oral methotrexate in the treatment of rheumatoid arthritis // Int J Rheum Dis. 2010; 13 (4): e83–e84. DOI: 10.1111/j.1756-185X.2010.01482.x.
69. Каратеев Д. Е., Лучихина Е. Л., Гриднева Г. И., Демидова Н. В. Применение подкожной формы метотрексата разных производителей в реальной клинической практике: сравнительное исследование // Альманах клинической медицины. 2019; 47 (5): 383–392. DOI: 10.18786/2072-0505-2019-47-055.
Рецензия
Для цитирования:
Чичасова Н.В., Лила А.М. Метотрексат в лечении ревматоидного артрита и псориатического артрита. Лечащий Врач. 2020;(7):42-51. https://doi.org/10.26295/OS.2020.12.42.002
For citation:
Chichasova N.V., Lila A.M. Methotrexate in the treatment of rheumatoid arthritis and psoriatic arthritis. Lechaschi Vrach. 2020;(7):42-51. (In Russ.) https://doi.org/10.26295/OS.2020.12.42.002
Просмотров: 89
Послать статью по эл. почте 
