Prognostic value of depression in patients with ischemic stroke

Background. Stroke, especially in the acute phase, leads to significant cognitive impairment. At the same time, such an intense psychologically traumatic event exacerbates the course of cerebrovascular process. Numerous studies have demonstrated that post-stroke depression affects approximately one-third of stroke survivors and serves as a predictor for significantly worse functional recovery, recurrent stroke and death. Post-stroke depression and dementia adversely affect the rehabilitation process, impair the recovery of activities of daily living and quality of life, as well as are associated with a significantly poorer prognosis.

Objective. To predict the recovery of the ability to self-care in stroke patients depending on the severity of depression

Materials and methods. A study of 199 patients with stroke in the acute period (2.2 ± 0.4 days) was conducted. Dynamic observation was performed after 12.4 ± 0.9 days. The severity of neurosomatic status was studied on the NIHSS scale, on the SHRM scale and the Bartel index; on the MRS scale, on the Beck depression scale, on the Spielberger anxiety scale, on the MMSE scale. The severity of arthropathy was assessed by X-ray and ultrasound examination. The serum levels of TRAIL and sCD95 were determined

Results. The established prognostic significance of the severity of depressive disorders in the formation of restrictions on the restoration of the ability to self-care, as well as masking criteria for cognitive defect in patients with ischemic stroke dictates the need for early involvement of medical psychologists not only at the hospital level, but also for the continuous management of patients at the outpatient stage.

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