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Treatment of laryngeal paresis after thyroid surgery

https://doi.org/10.51793/OS.2025.28.3.005

Abstract

Background. A frequent complication during operations on the thyroid gland is damage to the lower or upper laryngeal nerves, followed by the development of laryngeal paresis, with changes in breathing, phonation and impaired swallowing. In general, the incidence of postoperative complications varies considerably: different authors indicate a range from 0.2% to 15%, with an increase in persistent innervation disorders in repeated interventions (1-5%) compared with primary thyroid surgery (15-30%). If non-persistent paralyses are eliminated within 1-3 months after surgery, persistent disorders are a serious problem that requires a complex therapeutic approach and may cause disability of patients in certain professions.

Objective. The purpose of the article is to summarize and systematize the available literature data on therapeutic interventions for postoperative laryngeal paresis, to determine the most effective modern treatment methods; also consider preventive measures and ways to optimize early diagnosis of this complication of thyroid surgery.

Results. An analysis of conservative approaches to the treatment of laryngeal paresis (psychotherapy, physiotherapy, phonopedia, drug treatment) was carried out. Surgical methods for treating laryngeal paresis are considered, methods of prevention and ways to optimize early diagnosis of postoperative laryngeal paresis are presented.

Conclusion. Despite the active implementation of intraoperative monitoring and other preventive measures, complications are still possible during thyroid surgery. Comparative studies with large cohorts of patients assessing the superiority of one method over another are rare, and the results of small comparative studies are inconsistent. It is likely that a combined approach should be considered in the treatment of postoperative laryngeal paresis, taking into account possible regional health care facilities and patient preferences.

About the Authors

R. M. Zakhokhov
Kabardino-Balkarian State University named after Kh. M. Berbekov
Россия

Ruslan M. Zakhokhov, Cand. of Sci. (Med.), Associate Professor, Head of General Surgery Department

173 Chernyshevsky str., Nalchik, 360004



Z. N. Lovpache
Kabardino-Balkarian State University named after Kh. M. Berbekov
Россия

Zarema N. Lovpache, Cand. of Sci. (Med.), Associate Professor of General Surgery Department

173 Chernyshevsky str., Nalchik, 360004



A. A. Teuvov
Kabardino-Balkarian State University named after Kh. M. Berbekov
Россия

Aslan A. Teuvov, Cand. of Sci. (Med.), Associate Professor of General Surgery Department

173 Chernyshevsky str., Nalchik, 360004



A. M. Baziev
Kabardino-Balkarian State University named after Kh. M. Berbekov
Россия

Artur M. Baziev, Cand. of Sci. (Med.), Associate Professor of General Surgery Department

173 Chernyshevsky str., Nalchik, 360004



I. S. Teunikova
Kabardino-Balkarian State University named after Kh. M. Berbekov
Россия

Irina S. Teunikova, assistant of General Surgery Department

173 Chernyshevsky str., Nalchik, 360004



References

1. Nam I. C., Park Y. H. Pharyngolaryngeal symptoms associated with thyroid disease. Curr Opin Otolaryngol Head Neck Surg. 2017; 25: 469-74. DOI: 10.1097/MOO.0000000000000404.

2. Chen H. C., Pei Y. C., Fang T. J. Risk factors for thyroid surgery-related unilateral vocal fold paralysis. Laryngoscope. 2019; 129 (1): 275-283. DOI: 10.1002/lary.27336.

3. Dionigi G., Wu C. W., Kim H. Y., et al. Severity of recurrent laryngeal nerve injuries in thyroid surgery. World J Surg. 2016; 40: 1373-81.

4. Kulyaeva Yu. V., Lutsevich S. I. Paresis of the larynx after surgical interventions on the thyroid gland. BMIK. 2014; 5. URL: https://cyberleninka.ru/article/n/parez-gortani-posle-operativnyh-vmeshatelstv-na-schitovidnoy-zheleze (date of access: 06.17.2024). (In Russ.)

5. Kurz A., Leonhard M., Denk-Linnert D. M., et al. Comparison of voice therapy and selective electrical stimulation of the larynx in early unilateral vocal fold paralysis after thyroid surgery: A retrospective data analysis. Clin Otolaryngol. 2021 46: (3): 530-537. DOI: 10.1111/coa.13703.

6. Feng W., Ding M., Ren S. Acupuncture treatment for recurrent laryngeal nerve paralysis after thyroid surgery: a case report. Acupunct Med. 2021; 39 (4): 389-390. DOI: 10.1177/0964528420958715.

7. Baizhumanova A.S. Restorative methods of treatment of patients with laryngeal paralysis. J Clin Med Kaz. 2015; 3 (37): 9-13. (In Russ.)

8. Khitaryan A. G., Zakhokhov R. M., Lovpache Z. N. Hospital diagnosis of hypoparathyroidism and rehabilitation of patients with laryngeal paresis after subtotal subfascial and extrafascial resection of the thyroid gland. Scientific news. 2016; 3: 100-105. (In Russ.)

9. Laccourreye O., Malinvaud D., Ménard M., et al. Paralysies laryngées unilatérales de l'adulte: épidémiologie, symptomatologie, physiopathologie et traitement [Unilateral laryngeal nerve paralysis in the adult: Epidemiology, symptoms, physiopathology and treatment]. Presse Med. 2014; 43 (4 Pt 1): 348-52. French. DOI: 10.1016/j.lpm.2013.07.029.

10. Ptok M., Strack D. Electrical stimulation-supported voice exercises are superior to voice exercise therapy alone in patients with unilateral recurrent laryngeal nerve paresis: results from a prospective, randomized clinical trial. Muscle Nerve. 2008; 38 (2): 1005-1011. DOI: 10.1002/mus.21063.

11. Tam S., Sun H., Sarma S., et al. Medialization thyroplasty versus injection laryngoplasty: a cost minimization analysis. J of Otolaryngol – Head & Neck Surg. 2017; 46: 14. https://DOI.org/10.1186/s40463-017-0191-5.

12. Varvares M. A., Montgomery W. W., Hillman R. E. Teflon granuloma of the larynx: etiology, pathophysiology, and management. Annals of Otology, Rhinol Laryngol. 1995; 104: 511-515. 10.1177/000348949510400702.

13. Liao L. J., Wang C. T. Management of Unilateral Vocal Fold Paralysis after Thyroid Surgery with Injection Laryngoplasty: State of Art Review. Front Surg. 2022; 9: 876228. DOI: 10.3389/fsurg.2022.876228.

14. Fang T. J., Lee L. A., Wang C. J., et al. Intracordal fat assessment by 3-dimensional imaging after autologous fat injection in patients with thyroidectomy-induced unilateral vocal cord paralysis. Surgery. 2009; 146: 82-87. 10.1016/j.surg.2009.02.005.

15. Umeno H., Shirouzu H., Chitose S.-I., et al. Analysis of voice function following autologous fat injection for vocal fold paralysis. Otolaryngol Head Neck Surg. 2005; 132: 103-107. 10.1016/j.otohns.2004.09.016.

16. Laccourreye O., Papon J. F., Kania R., et al. Intracordal injection of autologous fat in patients with unilateral laryngeal nerve paralysis: long-term results from the patient's perspective. Laryngoscope. 2003; 113: 541-545. 10.1097/00005537200303000-00027.

17. McCulloch T. M., Andrews B. T., Hoffman H. T., et al. Long-term follow-up of fat injection laryngoplasty for unilateral vocal cord paralysis. Laryngoscope. 2002; 112: 1235-1238. 10.1097/00005537-200207000-00017.

18. Butterwick K. J., Nootheti P. K., Hsu J. W. Autologous fat transfer: an in-depth look at varying concepts and techniques. Facial Plast Surg Clin. 2007; 15: 99-111. 10.1016/j.fsc.2006.10.003.

19. Chao T.N., Mahmoud A., Rajasekaran K., et al. Medialisation thyroplasty with tensor fascia lata: a novel approach for reducing post-thyroplasty complications. J Laryngol Otol. 2018; 132 (4): 364-367. DOI: 10.1017/S0022215118000300.

20. Crolley V. E., Gibbins N. One hundred years of external approach medialisation thyroplasty. J Laryngol Otol. 2017; 131 (3): 202-208. DOI: 10.1017/S0022215116010033.

21. Abraham M. T., Gonen M., Kraus D. H. Complications of type I thyroplasty and arytenoid adduction. Laryngoscope. 2001; 111 (8): 1322-1329.

22. Liu C., Qiu Y., Zhang X., et al. Modified Arytenoid Adduction Operation for the Treatment of Unilateral Vocal Fold Paralysis. ORL J Otorhinolaryngol Relat Spec. 2022; 84 (3): 205-210. DOI: 10.1159/000517561.

23. Dispenza F., Dispenza C., Marchese D., et al. Treatment of bilateral vocal cord paralysis following permanent recurrent laryngeal nerve injury. Am J Otolaryngol. 2012; 33 (3): 285-8. DOI: 10.1016/j.amjoto.2011.07.009.

24. Rovó L., Ambrus A., Tóbiás Z., et al. Novel Endoscopic Arytenoid Medialization for Unilateral Vocal Fold Paralysis. Laryngoscope. 2021; 131 (3): E903-E910. DOI: 10.1002/lary.29001.

25. Watanabe A., Kimura Y., Tsukamoto S., et al. Artificial Nerve Conduit for Recurrent Laryngeal Nerve Reconstruction in Thyroid Surgery. Laryngoscope. 2023; 133 (7): 1773-1779. DOI: 10.1002/lary.30669.

26. Lee C., Stack B. C. Jr. Intraoperative neuromonitoring during thyroidectomy. Expert Rev Anticancer Ther. 2011; 11 (9): 1417-1427. DOI: 10.1586/era.11.97.

27. Uludag M., Aygun N., Kartal K., et al. Contribution of intraoperative neural monitoring to preservation of the external branch of the superior laryngeal nerve: a randomized prospective clinical trial. Langenbecks Arch Surg. 2017; 402 (6): 965-976. DOI: 10.1007/s00423-016-1544-7.

28. Aygun N., Kostek M., Isgor A., et al. Anatomical, Functional, and Dynamic Evidences Obtained by Intraoperative Neuromonitoring Improving the Standards of Thyroidectomy. Sisli Etfal Hastan Tip Bul. 2021; 55 (2): 146-155. DOI: 10.14744/SEMB.2021.45548.

29. Aygun N., Unlu M. T., Kostek M., et al. Intraoperative cricothyroid muscle electromyography may contribute to the monitorization of the external branch of the superior laryngeal nerve during thyroidectomy. Front Endocrinol (Lausanne). 2023; 14: 1303159. DOI: 10.3389/fendo.2023.1303159.

30. Stepanova Yu. E., Gotovyakhina T. V. Algorithm for examining patients with unilateral laryngeal paresis of unknown etiology in the practice of an otolaryngologist. Consilium Medicum. 2017; 11 (1): 37-40. (In Russ.)


Review

For citations:


Zakhokhov R.M., Lovpache Z.N., Teuvov A.A., Baziev A.M., Teunikova I.S. Treatment of laryngeal paresis after thyroid surgery. Lechaschi Vrach. 2025;(3):34-39. (In Russ.) https://doi.org/10.51793/OS.2025.28.3.005

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