Health indicators of children born after in vitro fertilization

Background. The most important achievement in modern medicine is the widespread introduction of assisted reproductive technologies. In Russia, in vitro fertilization has acquired well-known advantages. The use of this method made it possible to solve the problem of infertility for a large number of families and satisfy a woman’s natural need for motherhood. At the same time, the ultimate goal – the appearance of healthy offspring – can only be achieved through the joint efforts of reproductive specialists: clinical and laboratory specialists. The justified purpose of this study was to determine the most significant indicators of the health of newborns in Astrakhan after in vitro fertilization in relation to indicators of maternal health.
Materials and methods. The health indicators and developmental characteristics of 109 children born after in vitro fertilization in the city of Astrakhan and the Astrakhan region on the period 2017-2022, as well as the morbidity of their mothers, were studied. Methods of clinical and laboratory examination and modern methods of statistical analysis were used.
Results. It has been established that multiple pregnancies after in vitro fertilization are more often observed in women who have a history of a greater number of various pathological conditions, mainly anemia of pregnancy, endocrine diseases accompanied by edematous syndrome and obesity, as well as virus carriage against the background of multiple attempts at fertilization. A certain number of newborns after in vitro fertilization (12.4% from singleton and 18.4% from multiple pregnancies) had somatic pathology, which was accompanied by iron deficiency anemia. However, the relationship between the number of fetuses in pregnancy after in vitro fertilization, the sex of the newborn and the occurrence of early anemia in newborns has not been statistically confirmed.

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