Iron indicators in the umbilical blood of premature children born using IVF technology

It is vital to maintain iron metabolism within strict limits. Both the deficiency and excess of this metal in the body is manifested by numerous pathologies. Of interest is the comparison of iron metabolism in premature infants born using in vitro fertilization technology and premature infants born after conventional conception, because. such studies are being conducted for the first time and may contribute to improving the quality of care for such children. The purpose of the study is to conduct a comparative study of iron metabolism indicators, in particular, serum transferrin receptor (sTfR), ferritin, ferritin index (sTfR/logFer) and others in children born using IVF technology and children born after traditional conception. The main indicators of the hemogram and the main indicators of ferrokinetics have been studied. There were no significant differences in iron metabolism in full-term after traditional conception and as a result of the in vitro fertilization procedure. In premature infants born as a result of the IVF procedure, the hemoglobin level was 13.35 ± 0.55 g/dl, and the serum iron level was 16.16 ± 0.97 μmmol/l. ferritin level 128.64 ± 11.22 μg/l, level of soluble transferrin receptor 10.34 ± 0.57 mg/l, transferrin iron saturation 52.14 ± 3.27%, ferritin index 4.98 ± 0.1. According to the data obtained, premature babies born through the in vitro fertilization procedure had significant differences with premature babies born as a result of traditional conception in four indicators. 1. The level of ferritin in these children is significantly lower. 2. The ferritin index is significantly higher than in premature babies born as a result of traditional conception of the same gestational age. 3. the level of soluble transferrin receptor is significantly higher than in preterm infants born as a result of traditional conception of the same gestational age. 4. The percentage of transferrin saturation with iron in preterm infants born under the in vitro fertilization procedure does not differ from the percentage of transferrin saturation with iron in full-term healthy children, in contrast to premature children born as a result of traditional conception, in which this percentage is significantly lower.

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