Clinical and laboratory features of COVID-19 in young people

Clinical and laboratory parameters in young patients hospitalized in an infectious hospital with a diagnosis of COVID-19 were evaluated. The study included 89 patients with a diagnosis of «covid-19 Coronavirus infection» aged 18 to 44 years, the average age was 35,8 ± 1,6 years (59 (66,3%) men and 30 (33,7%) women). The clinical picture of the disease in most patients was characterized by the presence of bilateral viral pneumonia in 97% of cases. Concomitant diseases occurred in 32 patients (36%), most often in the group from 35 to 40 years, while the share of cardiovascular diseases and obesity was 51%. Mild severity was registered in 3 (3,4%) patients, average-in 86 (96,6%) patients. Men compared to women were more likely to have symptoms of intoxication (50,6% vs. 28,2%) and shortness of breath (28,2% vs. 10,1%), dry cough, dysgeusia and loss of appetite. In 73% of patients, respiratory failure (DN) was registered to varying degrees, and a quarter (26%) had no signs of DN. According to CT data, at the time of hospitalization, lung tissue damage of varying degrees was observed in 88% of patients. In dynamics, most patients showed a decrease in the degree of lung damage, but in 30% of cases there was no regression of lung damage at the end of the hospitalization period. COVID-19 in young patients is highly likely to develop complications in the form of pneumonia, the course of which is benign. The lack of regression of viral pneumonia more than one third of patients require follow-up all survivors and monitoring the laboratory parameters in dynamics for the identification and evaluation of consequences coronavirus infection and the need for further in-depth study of clinical and immunological characteristics of the course COVID-19 in different age groups.

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