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Лечащий Врач

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Окислительный стресс и эндометриоз: обзор литературы

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Аннотация

Активные формы кислорода (АФК) играют важную роль в модулировании многих физиологических функций репродуктивной системы, в том числе образовании эндометриоза, участвуют в патогенезе бесплодия; существует тонкий баланс между АФК и антиоксидантами в женском репродуктивном процессе, который поддерживает окислительно-восстановительный гомеостаз. Окислительный стресс возникает при условиях, когда нарушается баланс между выработкой АФК и антиоксидантной защитой, и это может быть связано либо с недостаточной антиоксидантной защитой, либо с избыточной выработкой АФК. Различные данные подтверждают роль окислительного стресса в развитии и прогрессировании эндометриоза. Это наблюдение может открыть путь для оценки терапевтических подходов, направленных на коррекцию окислительного дисбаланса: статус окислительного стресса может представлять собой ключ к лечению и, в конечном итоге, к предотвращению эндометриоза. В частности, в будущем клинические испытания помогут лучше прояснить эффективность антиоксидантов в качестве потенциальной терапии эндометриоза.

Об авторах

Л. В. Адамян
ФГБОУ ВО МГМСУ им. А. И. Евдокимова МЗ РФ
Россия


М. М. Сонова
ФГБОУ ВО МГМСУ им. А. И. Евдокимова МЗ РФ
Россия


К. Н. Арсланян
ФГБОУ ВО МГМСУ им. А. И. Евдокимова МЗ РФ
Россия


О. Н. Логинова
ФГБОУ ВО МГМСУ им. А. И. Евдокимова МЗ РФ
Россия


Э. И. Харченко

Россия


Список литературы

1. Kennedy S., Bergqvist A., Chapron C. et al. ESHRE guideline for the diagnosis and treatment of endometriosis // Human Reproduction. 2005, vol. 20, № 10, p. 2698-2704.

2. Augoulea A., Alexandrou A., Creatsa M., Vrachnis N., Lambrinoudaki I. Pathogenesis of endometriosis: the role of genetics, inflammation and oxidative stress // Archives of Gynecology and Obstetrics. 2012, vol. 286, № 1, p. 99-103.

3. Singh N., Lata K., Naha M., Malhotra N., Tiwari A., Vanamail P. Effect of endometriosis on implantation rates when compared to tubal factor in fresh non donor in vitro fertilization cycles // Journal of Human Reproductive Sciences. 2014, vol. 7, № 2, p. 143-147.

4. Houston D. E. Evidence for the risk of pelvic endometriosis by age, race and socioeconomic status // Epidemiologic Reviews. 1984, vol. 6, p. 167-191.

5. Bellelis P., Dias J. A. Jr., Podgaec S., Gonzales M., Baracat E. C., Abrao M. S. Epidemiological and clinical aspects of pelvic endometriosis-a case series // Revista da Associacao Medica Brasileira. 2010, vol. 56, № 4, p. 467-471.

6. Signorile P. G., Baldi A. Endometriosis: new concepts in the pathogenesis // The International Journal of Biochemistry & Cell Biology. 2010, vol. 42, № 6, p. 778-780.

7. Sampson J. A. Metastatic or embolic endometriosis, due to the menstrual dissemination of endometrial tissue into the venous circulation // The American Journal of Pathology. 1927, vol. 3, № 2, p. 93-110.43.

8. Vinatier D., Orazi G., Cosson M., Dufour P. Theories of endometriosis // European Journal of Obstetrics, Gynecology, and Reproductive Biology. 2001, vol. 96, № 1, p. 21-34.

9. Kennedy S., Mardon H., Barlow D. Familial endometriosis // Journal of Assisted Reproduction and Genetics. 1995, vol. 12, № 1, p. 32-34.

10. Christodoulakos G., Augoulea A., Lambrinoudaki I., Sioulas V., Creatsas G. Pathogenesis of endometriosis: the role of defective ‘immunosurveillance’ // The European Journal of Contraception & Reproductive Health Care. 2007, vol. 12, № 3, p. 194-202.

11. Augoulea A., Mastorakos G., Lambrinoudaki I., Christodoulakos G., Creatsas G. The role of the oxidative-stress in the endometriosis-related infertility // Gynecological Endocrinology. 2009, vol. 25, № 2, p. 75-81.

12. Agarwal A., Gupta S., Sharma R. K. Role of oxidative stress in female reproduction // Reproductive Biology and Endocrinology. 2005, vol. 3, p. 28.

13. Gupta S., Goldberg J. M., Aziz N., Goldberg E., Krajcir N., Agarwal A. Pathogenic mechanisms in endometriosis-associated infertility // Fertility and Sterility. 2008, vol. 90, № 2, p. 247-257.

14. Lousse J. C., van Langendonckt A., Defrere S., Ramos R. G., Colette S., Donnez J. Peritoneal endometriosis is an inflammatory disease // Frontiers in Bioscience (Elite Edition). 2012, vol. 4, p. 23-40.

15. Van Langendonckt A., Casanas-Roux F., Donnez J. Oxidative stress and peritoneal endometriosis // Fertility and Sterility. 2002, vol. 77, № 5, p. 861-870.

16. Wolfler M. M., Meinhold-Heerlein I. M., Henkel C. et al. Reduced hemopexin levels in peritoneal fluid of patients with endometriosis // Fertility and Sterility. 2013, vol. 100, № 3, p. 777-781.

17. Defrere S., Lousse J. C., Gonzalez-Ramos R., Colette S., Donnez J., van Langendonckt A. Potential involvement of iron in the pathogenesis of peritoneal endometriosis // Molecular Human Reproduction. 2008, vol. 14, № 7, p. 377-385.

18. Defrere S., van Langendonckt A., Vaesen S. et al. Iron overload enhances epithelial cell proliferation in endometriotic lesions induced in a murine model // Human Reproduction. 2006, vol. 21, № 11, p. 2810-2816.

19. Carvalho L. F., Samadder A. N., Agarwal A., Fernandes L. F., Abrao M. S Oxidative stress biomarkers in patients with endometriosis: systematic review // Archives of Gynecology and Obstetrics. 2012, vol. 286, № 4, p. 1033-1040.

20. Ngo C., Chereau C., Nicco C., Weill B., Chapron C., Batteux F. Reactive oxygen species controls endometriosis progression // The American Journal of Pathology. 2009, vol. 175, № 1, p. 225-234.

21. Lambrinoudaki I. V., Augoulea A., Christodoulakos G. E. et al. Measurable serum markers of oxidative stress response in women with endometriosis // Fertility and Sterility. 2009, vol. 91, № 1, p. 46-50.

22. Ota H., Igarashi S., Hatazawa J., Tanaka T. Distribution of heat shock proteins in eutopic and ectopic endometrium in endometriosis and adenomyosis // Fertility and Sterility. 1997, vol. 68, № 1, p. 23-28.

23. Verit F. F., Erel O., Celik N. Serum paraoxonase-1 activity in women with endometriosis and its relationship with the stage of the disease // Human Reproduction. 2008, vol. 23, № 1, p. 100-104.

24. Nasiri N., Moini A., Eftekhari-Yazdi P., Karimian L., Salman-Yazdi R., Arabipoor A. Oxidative stress statues in serum and follicular fluid of women with endometriosis // Cell Journal. 2017, vol. 18, № 4, p. 582-587.

25. Jackson L. W., Schisterman E. F., Dey-Rao R., Browne R., Armstrong D. Oxidative stress and endometriosis // Human Reproduction. 2005, vol. 20, № 7, p. 2014-2020.

26. Prieto L., Quesada J. F., Cambero O. et al. Analysis of follicular fluid and serum markers of oxidative stress in women with infertility related to endometriosis // Fertility and Sterility. 2012, vol. 98, № 1, p. 126-130.

27. Turkyilmaz E., Yildirim M., Cendek B. D. et al. Evaluation of oxidative stress markers and intra-extracellular antioxidant activities in patients with endometriosis // European Journal of Obstetrics, Gynecology, and Reproductive Biology. 2016, vol. 199, p. 164-168.

28. Bragatto F. B., Barbosa C. P., Christofolini D. M. et al. There is no relationship between paraoxonase serum level activity in women with endometriosis and the stage of the disease: an observational study // Reproductive Health. 2013, vol. 10, p. 32.

29. Turgut A., Ozler A., Goruk N. Y., Tunc S. Y., Evliyaoglu O., Gul T. Copper, ceruloplasmin and oxidative stress in patients with advanced-stage endometriosis // European Review for Medical and Pharmacological Sciences. 2013, vol. 17, № 11, p. 1472-1478.

30. Andrisani A., Dona G., Brunati A. M. et al. Increased oxidation-related glutathionylation and carbonic anhydrase activity in endometriosis // Reproductive Biomedicine Online. 2014, vol. 28, № 6, p. 773-779.

31. Donnez J., Binda M. M., Donnez O., Dolmans M. M. Oxidative stress in the pelvic cavity and its role in the pathogenesis of endometriosis // Fertility and Sterility. 2016, vol. 106, № 5, p. 1011-1017.

32. Santulli P., Chouzenoux S., Fiorese M. et al. Protein oxidative stress markers in peritoneal fluids of women with deep infiltrating endometriosis are increased // Human Reproduction. 2015, vol. 30, № 1, p. 49-60.

33. Osborn B. H., Haney A. F., Misukonis M. A., Weinberg J. B. Inducible nitric oxide synthase expression by peritoneal macrophages in endometriosis-associated infertility // Fertility and Sterility. 2002, vol. 77, № 1, p. 46-51.

34. Murphy A. A., Santanam N. Parthasarathy S. Endometriosis: a disease of oxidative stress? // Seminars in Reproductive Endocrinology. 1998, vol. 16, № 4, p. 263-273.

35. Polak G., Barczynski B., Kwasniewski W. et al. Low-density lipoproteins oxidation and endometriosis // Mediators of Inflammation. 2013, vol. 2013, Article ID624540, 4 p.

36. Mier-Cabrera J., Jimenez-Zamudio L., Garcia-Latorre E., Cruz-Orozco O., Hernandez-Guerrero C. Quantitative and qualitative peritoneal immune profiles, T-cell apoptosis and oxidative stress-associated characteristics in women with minimal and mild endometriosis // BJOG: An International Journal of Obstetrics and Gynaecology. 2011, vol. 118, № 1, p. 6-16.

37. Mier-Cabrera J., Genera-Garcia M., de la Jara-Diaz J., Perichart-Perera O., Vadillo-Ortega F., Hernandez-Guerrero C. Effect of vitamins C and E supplementation on peripheral oxidative stress markers and pregnancy rate in women with endometriosis // International Journal of Gynaecology and Obstetrics. 2008, vol. 100, № 3, p. 252-256.

38. Vinatier D., Cosson M., Dufour P. Is endometriosis an endometrial disease? // European Journal of Obstetrics, Gynecology, and Reproductive Biology. 2000, vol. 91, p. 113-125.

39. Sharma I., Dhaliwal L. K., Saha S. C., Sangwan S., Dhawan V. Role of 8-iso-prostaglandin F2alpha and 25-hydroxycholesterol in the pathophysiology of endometriosis // Fertility and Sterility. 2010, vol. 94, № 1, p. 63-70.

40. Singh A. K., Chattopadhyay R., Chakravarty B., Chaudhury K. Markers of oxidative stress in follicular fluid of women with endometriosis and tubal infertility undergoing IVF // Reproductive Toxicology. 2013, vol. 42, p. 116-124.

41. Nakagawa K., Hisano M., Sugiyama R., Yamaguchi K. Measurement of oxidative stress in the follicular fluid of infertility patients with an endometrioma // Archives of Gynecology and Obstetrics. 2016, vol. 293, № 1, p. 197-202.

42. Goud P. T., Goud A. P., Joshi N., Puscheck E., Diamond M. P., Abu-Soud H. M. Dynamics of nitric oxide, altered follicular microenvironment, and oocyte quality in women with endometriosis // Fertility and Sterility. 2014, vol. 102, № 1, p. 151-159.

43. Matsuzaki S., Schubert B. Oxidative stress status in normal ovarian cortex surrounding ovarian endometriosis // Fertility and Sterility. 2010, vol. 93, № 7, p. 2431-2432.

44. Tosti C., Pinzauti S., Santulli P., Chapron C., Petraglia F. Pathogenetic mechanisms of deep infiltrating endometriosis // Reproductive Sciences. 2015, vol. 22, № 9, p. 1053-1059.

45. Oner-Iyidogan Y., Kocak H., Gurdol F., Korkmaz D., Buyru F. Indices of oxidative stress in eutopic and ectopic endometria of women with endometriosis // Gynecologic and Obstetric Investigation. 2004, vol. 57, № 4, p. 214-217.

46. Andrade S. S., Azevedo Ade C., Monasterio I. C. et al. 17?-estradiol and steady-state concentrations of H2O2: antiapoptotic effect in endometrial cells from patients with endometriosis // Free Radical Biology & Medicine. 2013, vol. 60, p. 63-72.

47. Ngo C., Nicco C., Leconte M. et al. Protein kinase inhibitors can control the progression of endometriosis in vitro and in vivo // The Journal of Pathology. 2010, vol. 222, № 2, p. 148-157.

48. Kao, S. H. Huang H. C., Hsieh R. H., Chen S. C., Tsai M. C., Tzeng C. R. Oxidative damage and mitochondrial DNA mutations with endometriosis // Annals of the New York Academy of Sciences. 2005, vol. 1042, p. 186-194.

49. Kajihara H., Yamada Y., Kanayama S. et al. New insights into the pathophysiology of endometriosis: from chronic inflammation to danger signal // Gynecological Endocrinology. 2011, vol. 27, № 2, p. 73-79.

50. Da Broi M. G., Navarro P. A. Oxidative stress and oocyte quality: ethiopathogenic mechanisms of minimal/mild endometriosis-related infertility // Cell and Tissue Research. 2016, vol. 364, № 1, p. 1-7.

51. Shigetomi H., Higashiura Y., Kajihara H., Kobayashi H. A potential link of oxidative stress and cell cycle regulation for development of endometriosis // Gynecological Endocrinology. 2012, vol. 28, № 11, p. 897-902.

52. Ito F., Yamada Y., Shigemitsu A. et al. Role of oxidative stress in epigenetic modification in endometriosis // Reproductive Sciences. 2017, vol. 60.

53. Yamada Y., Shigetomi H., Onogi A. et al. Redox-active iron-induced oxidative stress in the pathogenesis of clear cell carcinoma of the ovary // International Journal of Gynecological Cancer. 2011, vol. 21, № 7, p. 1200-1207.

54. Wright K. R., Mitchell B., Santanam N. Redox regulation of microRNAs in endometriosis-associated pain // Redox Biology. 2017, vol. 12, p. 956-966.

55. Hevir N., Ribic-Pucelj M., Lanisnik R. T. Disturbed balance between phase I and II metabolizing enzymes in ovarian endometriosis: a source of excessive hydroxy-estrogens and ROS?» Molecular and Cellular Endocrinology. 2013, vol. 367, № 1-2, p. 74-84.

56. Kobayashi H. Potential scenarios leading to ovarian cancer arising from endometriosis // Redox Report. 2016, vol. 21, № 3, p. 119-126.

57. Iwabuchi T., Yoshimoto C., Shigetomi H., Kobayashi H. Oxidative stress and antioxidant defense in endometriosis and its malignant transformation // Oxidative Medicine and Cellular Longevity. 2015, vol. 2015, Article ID848595, 7 p.

58. Agarwal A., Gupta S., Sekhon L., Shah R. Redox considerations in female reproductive function and assisted reproduction: from molecular mechanisms to health implications // Antioxidants & Redox Signaling. 2008, vol. 10, № 8, p. 1375-144.

59. Agarwal A., Aponte-Mellado A., Premkumar B. J., Shaman A., Gupta S. The effects of oxidative stress on female reproduction: a review // Reproductive Biology and Endocrinology. 2012, vol. 10, p. 49.

60. Harlev A., Gupta S., Agarwal A. Targeting oxidative stress to treat endometriosis // Expert Opinion on Therapeutic Targets. 2015, vol. 19, № 11, p. 1447-1464.


Рецензия

Для цитирования:


Адамян Л.В., Сонова М.М., Арсланян К.Н., Логинова О.Н., Харченко Э.И. Окислительный стресс и эндометриоз: обзор литературы. Лечащий Врач. 2019;(12):20-25.

For citation:


Adamyan L.V., Sonova M.M., Arslanyan K.N., Loginova O.N., Kharchenko E.I. Oxidative stress and endometriosis: review of the literature. Lechaschi Vrach. 2019;(12):20-25. (In Russ.)

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