The problem of the diagnosis of early congenital syphilis: a case report
https://doi.org/10.26295/OS.2021.43.20.004
Abstract
Congenital syphilis is still a public health concern, and syphilis can go unnoticed in pregnant women, even in developed countries with active antenatal care. Currently, according to the International Classification of Diseases (ICD-10), early (in children under 2 years of age) and late congenital syphilis (in children over 2 years of age) are distinguished. Features of the clinical course of early congenital syphilis make it possible to divide it into early congenital syphilis of infancy (up to 1 year) and early childhood (from 1 to 2 years). The signs of congenital syphilis are diverse and a high index of suspicion must be maintained to make the diagnosis. Early congenital syphilis usually appears in the neonatal period and seldom later than 3-4 months of life and hardly ever in children older than one year of age. We report 20-month-old boy with congenital syphilis who presented bone lesions in the lower extremities and cutaneous eruptions and remained undiagnosed until his mother was diagnosed with secondary syphilis. The article also highlights the possible difficulties in diagnosing syphilis in children of early childhood.
About the Authors
V. I. SurganovaРоссия
Ekaterinburg
N. V. Polyakova
Россия
Ekaterinburg
N. K. Levchik
Россия
Ekaterinburg
N. V. Zilberberg
Россия
Ekaterinburg
T. A. Syrneva
Россия
Ekaterinburg
References
1. Kungurov N. V., Ufimtseva M. A., Shakurov I. G. i dr. Epidemiologicheskiye i sotsial'nyye aspekty zabolevayemosti sifilisom, prioritetnyye zadachi po predotvrashcheniyu dal'neyshego rasprostraneniya infektsii. [Epidemiological and social aspects of the incidence of syphilis, priority tasks to prevent further spread of infection.] Yekaterinburg: Izd-vo Ural. un-ta, 2008. Pp. 8-31.
2. Guarner J., Greer H. W., Barlett J. D. Congenital syphilis in a newborn; an immunopathologicstady // Med. Pathol. 1999; 12 (1): 82-87.
3. Bakuridze N. A. Sostoyaniye zdorov'ya detey pervogo mesyatsa zhizni s diagnozom ranniy vrozhdennyy sifilis [The state of health of children of the first month of life diagnosed with early congenital syphilis] Tezisy nauchnykh trudov Pervogo Rossiyskogo kongressa dermatovenerologov. SPb, 2003. P. 78.
4. Syrneva T. A., Malishevskaya N. P., Makarenko A. V. Klinikoepidemiologicheskiye aspekty vrozhdennogo sifilisa v Rossii [Clinical and epidemiological aspects of congenital syphilis in Russia] Rossiyskiy zhurnal kozhnykh i venericheskikh bolezney. 2015. T. 18. № 2. Pp. 57-60.
5. Gorlanov I. A., Milyavskaya I. R., Leina L. M. Klinika, diagnostika i lecheniye rannego vrozhdennogo sifilisa [Clinic, diagnosis and treatment of early congenital syphilis] Vestnik dermatologii i venerologii. 2009. № 3. Pp. 73-77.
6. Woods C. R. Syphilis in children: congenital and acquired // Semin Pediatr Infect Dis. 2005; 16: 245−257. DOI: 10.1053/j.spid.2005.06.005.
7. Prokhorenkov V. I. Sifilis: il. ruk-vo. [Syphilis: illustrated manual] M.: Meditsinskaya kniga, 2002. 298 p.
8. Selyunina O. V. K klinike rannego vrozhdennogo sifilisa [To the clinic of early congenital syphilis] Vestnik postdiplomnogo meditsinskogo obrazovaniya. 2002. № 1. Pp. 95-96.
9. Rodionov A. N. Sifilis: prakticheskoye rukovodstvo. [Syphilis: a practical guide.] 3-ye izd. SPb: OOO «Piter», 2007. 315 p.
10. Rossiyskoye obshchestvo dermatovenerologov. Dermatovenerologiya: 2010. Klinicheskiye rekomendatsii: 4-ye izd., pererab. i dop. Sifiliticheskaya infektsiya [Russian Society of Dermatovenereologists. Dermatovenereology: 2010. Clinical guidelines: 4th ed., Revised. and add. Syphilitic Infection] Pod red. A. A. Kubanovoy. M.: Izd. DEKS-Press, 2010. Pp. 347-385.
11. Pankratov O. V. Epidemiologicheskiye i klinicheskiye aspekty sifiliticheskoy infektsii u beremennykh i novorozhdennykh v Respublike Belarus' [Epidemiological and clinical aspects of syphilitic infection in pregnant women and newborns in the Republic of Belarus] Klinicheskaya dermatologiya i venerologiya. 2014. T. 12. № 6. Pp. 130-135.
12. Simmank K. C., Pettifor J. M. Unusual presentation of congenital syphilis // Ann Trop Paediatr. 2000; 20 (2): 105-107.
13. Jin Ki Kim, Se Rim Choi, Hee Jung Lee, Dong Hyun Kim, Moon Soo Yoon, Heui Seung Jo. Congenital Syphilis Presenting with a Generalized Bullous and Pustular Eruption in a Premature Newborn // Ann Dermatol. 2011. Vol. 23, Suppl. 1.
14. Berkowitz K. M., Stampf K., Baxi L. False negative screening tests for syphilis in pregnant women (letter) // N Engl J Med. 1990; 322: 270-271.
15. Torshina I. Ye. K probleme differentsial'noy diagnostiki vrozhdennogo i priobretennogo sifilisa u detey (po materialam Smolenskoy oblasti) [To the problem of differential diagnosis of congenital and acquired syphilis in children (based on the materials of the Smolensk region)] Reproduktivnoye zdorov'ye detey i podrostkov. 2010. № 2. Pp. 87-93.
16. Makarenko A. V. Epidemiologicheskiye i sotsial'nyye aspekty vrozhdennogo sifilisa i osnovnyye napravleniya po yego kontrolyu i profilaktike a ural'skom regione: [Epidemiological and social aspects of congenital syphilis and the main directions for its control and prevention in the Ural region] dis. kand. med. nauk. Yekaterinburg, 2007. 129 p.
17. Martynov G. P., Prokhorenkov V. I., Kuznetsova N. F. Ranniy vrozhdennyy sifilis: epidemiologicheskiye i kliniko-laboratornyye aspekty techeniya [Early congenital syphilis: epidemiological and clinical and laboratory aspects of the course] Klin. derm. i venerologiya. 2014. № 2. Pp. 27-34.
18. Kliegman R. M., Stanton B. F., Schor N. F., Geme J. W. S. III, Behrman R. E. Syphilis (Treponemapallidum). In Nelson: Textbook of Pediatrics. Elsevier, Philadelphia, Pa, USA. 2012; 19th edition: 1264.
19. Herremans T., Kortbeek L., Notermans D. W. A review of diagnostic tests for congenital syphilis in newborns // Eur J Clin Microbiol Infect Dis. 2010; 29: 495-501.
20. Pashkov B. M. Pozdniy vrozhdennyy sifilis: uchebnik. [Late congenital syphilis: textbook] M., 1955. 215 p.
21. Zatorskaya N. F. Znacheniye rentgenografii trubchatykh kostey v diagnostike rannego vrozhdennogo sifilisa [The value of tubular bone radiography in the diagnosis of early congenital syphilis] Ross. zhurnal kozhn. i venerich. bol. 2009. № 6. Pp. 37-41.
Review
For citations:
Surganova V.I., Polyakova N.V., Levchik N.K., Zilberberg N.V., Syrneva T.A. The problem of the diagnosis of early congenital syphilis: a case report. Lechaschi Vrach. 2021;(1):20-23. (In Russ.) https://doi.org/10.26295/OS.2021.43.20.004
JATS XML


















