Combination of nephroblastoma and bilateral vesicoureteral reflux in a 7-year-old girl (description of a clinical case)
https://doi.org/10.51793/OS.2026.29.1.002
Abstract
Background. We present a previously undescribed clinical case of a combination of nephroblastoma and bilateral vesicoureteral reflux in a 7-year-old girl. Vesicoureteral reflux is one of the most common congenital uropathies in children. High degrees of vesicoureteral reflux and frequently recurring urinary tract infections lead to progressive kidney damage with the development of reflux nephropathy (RN). Nephroblastoma or Wilms' tumor is a highly malignant embryonic tumor of the kidney in children. Despite the low incidence, it is the most common among all malignant neoplasms of the kidney. The clinical picture is diverse and can consist of nonspecific general and local symptoms, the severity of which depends on the localization, size, and metastasis of nephroblastoma. Due to ethnic characteristics, the girl first underwent a medical examination at the age of 7.
Results. The results of the examination of the urinary system revealed combined bilateral damage to the kidneys and upper urinary tract, Wilms tumor of the right kidney, bilateral grade IV vesicoureteral reflux on the right, grade V on the left in a secondary shrunken kidney, secondary hypochromic anemia of mild degree. Pediatricians together with urologists, nephrologists, oncologists, and transplantologists developed a treatment strategy for the patient.
About the Authors
D. A. Kartashova
Moscow Regional Clinical Research Institute named after M. F. Vladimirsky
Россия
Россия
Darya A. Kartashova, Junior Researcher, Department of Pediatrics
61/2 Schepkina str., Moscow, 129110
T. A. Bokova
Moscow Regional Clinical Research Institute named after M. F. Vladimirsky
Россия
Россия
Tatyana A. Bokova, Dr. of Sci. (Med.), Associate Professor, Head of the Department of Pediatrics, Head of the Department of Children's Diseases
61/2 Schepkina str., Moscow, 129110
A. B. Sobolevskiy
Paracelsus Children's Medical Center
Россия
Россия
Alexander B. Sobolevskiy, Cand. of Sci. (Med.), pediatric urologist
143500, Istra, Ryabkina str., 16
T. N. Petrenets
Paracelsus Children's Medical Center
Россия
Россия
Tatyana N. Petrenets, ultrasound diagnostics doctor
143500, Istra, Ryabkina str., 16
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For citations:
Kartashova D.A., Bokova T.A., Sobolevskiy A.B., Petrenets T.N. Combination of nephroblastoma and bilateral vesicoureteral reflux in a 7-year-old girl (description of a clinical case). Lechaschi Vrach. 2026;(1):16-20. (In Russ.) https://doi.org/10.51793/OS.2026.29.1.002
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