Complex therapy of atopic dermatitis: experience of using therapeutic cosmetics

Background. Currently, to the use of medicinal cosmetics is given a special role in the therapy of chronic dermatoses. Taking into account the fact that the treatment of diseases such as eczema and atopic dermatitis is predominantly external, a constant search is being carried out for means and methods that, while highly effective, would be safe and well tolerated with long-term use. The basic external drugs are topical glucocorticosteroids, but their use over a long period of time is unacceptable due to the possible development of local and systemic side effects. Atopic dermatitis and eczema are chronic itchy dermatoses, in which one of the key links in the pathogenesis is skin barrier disorders and immune-mediated inflammation. Since xerosis and epidermal barrier disorders impair the absorption of external glucocorticosteroids and prevent their penetration into the dermis, where infiltration and production of proinflammatory cytokines predominantly occurs, it is necessary to prescribe emollient therapy from the first day of treatment as an adjunct to the main treatment. The integrity and sufficient degree of hydration of the stratum corneum, which is achieved through these agents, contribute to increased permeability for external glucocorticosteroids and, in turn, a more pronounced effect. Taking into account the certain role of epidermal barrier disorders in the development of atopic dermatitis and eczema, external therapy in the form of moisturizing and fattening agents is basic.

Objective. To study the efficacy of therapeutic cosmetics in the form of a combination of shower gel and cream for dry and sensitive skin in the complex therapy of patients with chronic pruritic dermatoses (atopic dermatitis and eczema). The prospective multicentre study included 77 patients diagnosed with atopic dermatitis and eczema, including 51 women and 26 men.

Conclusion. The results of the conducted study demonstrated high efficiency of the joint application of shower gel and cream for dry and sensitive skin in the complex therapy of atopic dermatitis and eczema.

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