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Current trends in local injection therapy of degenerative-dystrophic diseases of the musculoskeletal system

https://doi.org/10.51793/OS.2024.27.7.006

Abstract

Background. Modern preparations – hyaluronic acid-based synovial fluid prostheses significantly help to improve the results of treatment of deforming osteoarthritis and diseases of periarticular tissues. Cartilage deficiency, degenerative changes in the surrounding soft tissues (tendons of rotator cuff muscles) require specific pathogenetic therapy. Several minimally invasive approaches exist to address these uncommon complications, which mainly consist of intra-articular injections of molecules such as hyaluronic acid. In preclinical and clinical studies, preparations of low molecular weight hyaluronic acids have been found to have, in addition to their mechanical positive properties (viscoinduction), also significant anti-inflammatory and analgesic properties.

Objective. Improving the results of conservative treatment of patients with degenerative-dystrophic diseases of the musculoskeletal system. Materials and methods. The authors present a perfect method of complex conservative treatment using modern trends in local injection therapy, developed to improve the quality of life of patients. 3 clinical examples are considered. The effectiveness of this technique has been proven.

Results. The use of local injection therapy using various types of hyaluronic acid as part of the complex conservative treatment of degenerative and dystrophic diseases of the musculoskeletal system significantly improved the effectiveness of treatment, increasing the mechanical, analgesic and anti-inflammatory effect.

Conclusion. The developed scheme of complex conservative therapy of degenerative-dystrophic diseases of the musculoskeletal system using local injection therapy of various forms of hyaluronic acid helps to improve treatment results and improves the quality of life of the patient.

About the Authors

S. D. Sirazitdinov
Kazan State Medical Academy; Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan
Россия

Sayar D. Sirazitdinov - orthopedic traumatologist, Head of the Traumatology Department of the Consultative Polyclinic of the Republican Scientific and Practical Center for Traumatology, Senior researcher of the Research Department, State Autonomous Healthcare Institution Republican Clinical Hospital of the Republic of Tatarstan; Assistant of the Department of Traumatology and Orthopedics, Kazan State Medical Academy – branch of the Federal State Budgetary Educational Institution of Additional Professional Education Russian Medical Academy of Continuing Professional Education of the Ministry of Health of the Russian Federation.

138 Orenburg tract, Kazan, 420064; 36 Butlerova str., Kazan, 420012



I. O. Pankov
Kazan State Medical Academy; Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan
Россия

Igor O. Pankov - Dr. of Sci. (Med.), Professor, Head of the Department of Traumatology and Orthopedics, Kazan State Medical Academy – branch of the Federal State Budgetary Educational Institution of Additional Professional Education Russian Medical Academy of Continuing Professional Education of the Ministry of Health of the Russian Federation; Chief Scientist of the Research Department, State Autonomous Healthcare Institution Republican Clinical Hospital of the Republic of Tatarstan.

36 Butlerova str., Kazan, 420012; 138 Orenburg tract, Kazan, 420064



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Review

For citations:


Sirazitdinov S.D., Pankov I.O. Current trends in local injection therapy of degenerative-dystrophic diseases of the musculoskeletal system. Lechaschi Vrach. 2024;(7):41-47. (In Russ.) https://doi.org/10.51793/OS.2024.27.7.006

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