Polymorbidity in dermatological practice: symbiosis of autoimmune diseases

Abstract

Background. In modern dermatologist practice, cases of combined dermatological pathology are increasingly encountered, which complicates the differential diagnostic search, leads to a delay in the start of treatment and disease progression. The study of combined dermatoses from the point of view of etiological and pathophysiological mechanisms of occurrence, their mutual influence on each other, diagnostic markers and the impact of complex therapy on each disease is of particular importance for further prognosis in patients with chronic dermatoses.
Objective. The article presents two clinical observations of patients with combined dermatological pathology: systemic lupus erythematosus and psoriasis.
Materials and methods. The difficulties of making a final clinical diagnosis are demonstrated. The importance of a thorough differential diagnostic search, close attention to patients with long-existing rashes, and interdisciplinary interaction of specialists is reflected.
Results. Increased awareness among both dermatologists and allied physicians will promote clinical vigilance, which will improve the quality of life in this group of patients.
Conclusion. Identification of comorbid pathology in the early stages of the development of chronic diseases will contribute to improving the quality of life and the likelihood of a favorable outcome even at the outpatient stage of medical care. Early identification of indicators of the systemic nature of the process and timely initiation of therapy will improve the quality of medical care for patients with multimorbid pathology. In this regard, this article presents our own clinical observations.