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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">lvrach</journal-id><journal-title-group><journal-title xml:lang="ru">Лечащий Врач</journal-title><trans-title-group xml:lang="en"><trans-title>Lechaschi Vrach</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-5175</issn><issn pub-type="epub">2687-1181</issn><publisher><publisher-name></publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51793/OS.2022.25.6.002</article-id><article-id custom-type="elpub" pub-id-type="custom">lvrach-919</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИНЕКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GYNECOLOGY</subject></subj-group></article-categories><title-group><article-title>Дифференциальная диагностика новообразования придатков матки с использованием контраст-усиленного ультразвука (клиническое наблюдение)</article-title><trans-title-group xml:lang="en"><trans-title>Differential diagnosis of ovarian neoplasm using contrast-enhanced ultrasound (clinical case)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9949-9192</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сафонова</surname><given-names>Н. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Safonova</surname><given-names>N. Е.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сафонова Наталья Евгеньевна, аспирант кафедры акушерства и гинекологии; врач акушер-гинеколог</p><p>125993, Москва, ул. Баррикадная, 2/1, стр. 1</p><p>105077, Москва, ул. 11-я Парковая, 32</p></bio><bio xml:lang="en"><p>Nataliya Е. Safonova, PhD student of the Department of Obstetrics and Gynecology; obstetrician gynecologist</p><p>2/1 b. 1 Barricadnaya str., Moscow, 125993</p><p>32 11th Parkovaya str., Moscow, 105077</p></bio><email xlink:type="simple">rediska2406@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9183-7030</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Подзолкова</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Podzolkova</surname><given-names>N. М.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Подзолкова Наталия Михайловна, доктор медицинских наук, профессор, заведующая кафедрой акушерства и гинекологии</p><p>125993, Москва, ул. Баррикадная, 2/1, стр. 1</p></bio><bio xml:lang="en"><p>Nataliya М. Podzolkova, Dr. of Sci. (Med.), Professor, Head of the Department of Obstetrics and Gynecology</p><p>2/1 b. 1 Barricadnaya str., Moscow, 125993</p></bio><email xlink:type="simple">podzolkova@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5351-0854</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осадчев</surname><given-names>В. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Osadchev</surname><given-names>V. В.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Осадчев Василий Борисович, кандидат медицинских наук, доцент кафедры акушерства и гинекологии; заведующий гинекологическим отделением, врач акушер-гинеколог</p><p>125993, Москва, ул. Баррикадная, 2/1, стр. 1</p><p>105077, Москва, ул. 11-я Парковая, 32</p></bio><bio xml:lang="en"><p>Vasily В. Osadchev, MD, Associate Professor of the Department of Obstetrics and Gynecology; Head of the Department of Obstetrics and Gynecology, obstetrician gynecologist</p><p>2/1 b. 1 Barricadnaya str., Moscow, 125993</p><p>32 11th Parkovaya str., Moscow, 105077</p></bio><email xlink:type="simple">vosadchev@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6260-2734</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабков</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Babkov</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бабков Кирилл Владимирович, кандидат медицинских наук, доцент кафедры акушерства и гинекологии; врач акушер-гинеколог</p><p>125993, Москва, ул. Баррикадная, 2/1, стр. 1</p><p>105077, Москва, ул. 11-я Парковая, 32</p></bio><bio xml:lang="en"><p>Kirill V. Babkov, MD, Associate Professor of the Department of Obstetrics and Gynecology; obstetrician gynecologist</p><p>2/1 b. 1 Barricadnaya str., Moscow, 125993</p><p>32 11th Parkovaya str., Moscow, </p></bio><email xlink:type="simple">kirill.babkov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0881-0740</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фадеев</surname><given-names>И. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Fadeev</surname><given-names>I. Е.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Фадеев Игорь Евгеньевич, кандидат медицинских наук, доцент кафедры акушерства и гинекологии</p><p>125993, Москва, ул. Баррикадная, 2/1, стр. 1</p><p>109240, Москва, ул. Яузская, 11</p></bio><bio xml:lang="en"><p>Igor Е. Fadeev, MD, Associate Professor of the Department of Obstetrics and Gynecology; obstetrician gynecologist</p><p>2/1 b. 1 Barricadnaya str., Moscow, 125993</p><p>11 Yauzskaya str., Moscow, 109240</p></bio><email xlink:type="simple">iefadeev@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования Российская медицинская академия непрерывного профессионального образования Министерства здравоохранения Российской Федерации; Государственное бюджетное учреждение здравоохранения города Москвы Городская клиническая больница имени Д. Д. Плетнёва Департамента здравоохранения города Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Additional Professional Education Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation; D. D. Pletnev City Clinical Hospital of Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования Российская медицинская академия непрерывного профессионального образования Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Additional Professional Education Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования Российская медицинская академия непрерывного профессионального образования Министерства здравоохранения Российской Федерации; Государственное бюджетное учреждение здравоохранения города Москвы Городская клиническая больница имени И. В. Давыдовского Департамента здравоохранения города Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Additional Professional Education Russian Medical Academy of Continuous Professional; I. V. Davidovsky City Clinical Hospital of Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>14</day><month>07</month><year>2022</year></pub-date><volume>0</volume><issue>5-6</issue><fpage>14</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сафонова Н.Е., Подзолкова Н.М., Осадчев В.Б., Бабков К.В., Фадеев И.Е., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Сафонова Н.Е., Подзолкова Н.М., Осадчев В.Б., Бабков К.В., Фадеев И.Е.</copyright-holder><copyright-holder xml:lang="en">Safonova N.Е., Podzolkova N.М., Osadchev V.В., Babkov K.V., Fadeev I.Е.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.lvrach.ru/jour/article/view/919">https://journal.lvrach.ru/jour/article/view/919</self-uri><abstract><p>Диагностика новообразований придатков матки является одной из самых сложных задач в практической гинекологии. В области придатков матки могут располагаться как истинные опухоли, так и опухолевидные образования, а также образования, исходящие из других органов брюшной полости и малого таза. Трудности своевременной диагностики опухолей яичников заключаются в отсутствии клинически выраженных предопухолевых состояний и усугубляются их сложным патогенезом. Ввиду высокого риска злокачественного перерождения опухолей яичников и невозможности дигностировать предраковое состояние проблема раннего выявления новообразования яичника представляется наиболее актуальной. На сегодняшний день отнесение опухоли к категории злокачественной и определение ее стадии возможно только после оперативного вмешательства c последующим гистологическим исследованием удаленных тканей. Дальнейшая тактика ведения больной основывается на результатах гистологического исследования. Описание данного клинического случая может помочь расширить возможности и знания практикующих врачей в подходе к дифференциальной диагностике новообразований придатков. Пациентка Н., 33 лет, в апреле 2020 года обратилась в гинекологическое отделение ГБУЗ ГКБ им. Д. Д. Плетнёва по направлению из женской консультации с диагнозом: киста левого яичника, болевой синдром. Предметом интереса данного клинического случая является проведение дифференциальной диагностики новообразования яичника. Принимая во внимание результаты предварительного обследования, в плане дифференциальной диагностики можно думать о злокачественном новообразовании яичника, рецидиве дермоидной кисты яичника, фиброме яичника, миоме матки с субсерозным ростом узла. Поэтому важной задачей является создание оптимальных алгоритмов диагностики и маршрутизации пациенток при подозрении на опухоль придатков. Современная диагностика опухолей яичников не может основываться на одном методе исследования, а требует целого комплекса диагностических мероприятий, определяющих тактику ведения пациенток в каждом конкретном случае.</p></abstract><trans-abstract xml:lang="en"><p>Diagnosis of ovarian neoplasms is one of the most difficult tasks in practical gynecology. In the area of the uterine appendages, both true tumors and tumor-like formations, as well as formations emanating from other organs of the abdominal cavity and small pelvis, can be located. Difficulties in the timely diagnosis of ovarian tumors lie in the absence of clinically expressed precancerous conditions and are aggravated by their complex pathogenesis. Due to the high risk of malignant rebirth of ovarian tumors and the inability to diagnose a precancerous condition, the problem of early detection of ovarian neoplasm seems to be the most relevant. Today, it is possible to classify a tumor as malignant and determine its stage only after surgical operation with subsequent histological examination of removed tissues. Further patient treatment are based on the results of a histological examination. The description of this clinical case may help to enhance the capabilities and knowledge of practitioners in their approach to differential diagnosis of ovarian tumors. Patient N., 33 years old in April 2020, turned to the hospital named after D.D. Pletnev in the direction from the women's consultation with a diagnosis: left ovarian cyst, pain syndrome. The subject of interest of this clinical case is the differential diagnosis of ovarian neoplasm. Taking into account the results of the preliminary examination, we can think about a malignant ovarian neoplasm, relapse of the ovarian dermoid cyst, ovarian fibroma, uterine myoma with subserosal localization of node. That’s why an important task is to create optimal algorithms for diagnosing and routing patients in case of suspicion of an adnexal tumor. Modern diagnostics of ovarian tumors cannot be based on one research method, but requires a whole range of diagnostic measures that determine the tactics of introducing patients in each specific case.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>яичник</kwd><kwd>новообразования придатков матки</kwd><kwd>диагностика</kwd><kwd>алгоритм</kwd><kwd>предраковое состояние</kwd><kwd>гистологическое исследование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ovary</kwd><kwd>ovarian neoplasms</kwd><kwd>diagnosis</kwd><kwd>algorithm</kwd><kwd>precancerous condition</kwd><kwd>histological examination</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ortiz-Muñoz B., Aznar-Oroval E., García García A., Covisa Peris A., Perez Ballestero P., Sanchez Yepes M., Garcia Lozano T., Illueca Ballester C., García Garcia E. 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