References

lvrach

Лечащий Врач

Lechaschi Vrach

1560-51752687-1181

ООО «Издательство "Открытые системы"»

10.26295/OS.2020.67.71.005

lvrach-82

Research Article

Статьи

Лекарственная болезнь печени. Клинический случай цирроза печени на фоне приема нестероидных противовоспалительных препаратов

liver disease. Clinical case of liver cirrhosis against the background of non-steroidal anti-inflammatory drugs

Плотникова

Е. Ю.

Plotnikova

E. Yu.

eka-pl@rambler.ru

Баранова

Е. Н.

Baranova

E. N.

noemail@neicon.ru

Воросова

О. А.

Vorosova

O. A.

noemail@neicon.ru

Карягина

М. С.

Кaryagina

M. S.

noemail@neicon.ru

Краснов

К. А.

Krasnov

K. A.

noemail@neicon.ru

ФГБОУ ВО КемГМУ МЗ РФRussian Federation

2020

23062021

022834

2021

Плотникова Е.Ю., Баранова Е.Н., Воросова О.А., Карягина М.С., Краснов К.А.

Plotnikova E.Y., Baranova E.N., Vorosova O.A., Кaryagina M.S., Krasnov K.A.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://journal.lvrach.ru/jour/article/view/82

Лекарственные поражения печени составляют около 10% от всех побочных реакций макроорганизма, связанных с применением фармакологических препаратов. В статье приводятся основные механизмы лекарственного повреждения печени. Диагностика лекарственного повреждения печени часто бывает затруднительной и требует от врача не только необходимости тщательного сбора анамнеза пациента с развившимся заболеванием, но и хорошей ориентации в его клинических и морфологических проявлениях. Приводится клинический пример лекарственного цирроза печени, когда пациентка много лет злоупотребляла приемом различных нестероидных противовоспалительных препаратов, что привело к фатальному исходу.

Drug lesions of the liver account for about 10% of all side reactions of the macrobody associated with the use of pharmacological preparations. The article describes the main mechanisms of drug injury to the liver. Diagnosis of drug liver damage is often difficult and requires the physician not only to carefully collect the history of the patient with the developed disease, but also to have a good orientation in its clinical and morphological manifestations. A clinical case of drug cirrhosis of the liver is given, when the patient for many years overused various non-steroidal anti-inflammatory drugs, which led to a fatal outcome.

ГастроэнтерологияГепатотоксические препаратыКоллоквиумЛекарственная болезнь печениНестероидные противовоспалительные препаратыТерапияЦирроз печени

drug-induced liver diseasenon-steroidal anti-inflammatory drugshepatotoxic drugscirrhosis of the liver

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The authors declare that there are no conflicts of interest present.