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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">lvrach</journal-id><journal-title-group><journal-title xml:lang="ru">Лечащий Врач</journal-title><trans-title-group xml:lang="en"><trans-title>Lechaschi Vrach</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-5175</issn><issn pub-type="epub">2687-1181</issn><publisher><publisher-name>ООО «Издательство "Открытые системы"»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51793/OS.2021.35.60.001</article-id><article-id custom-type="elpub" pub-id-type="custom">lvrach-729</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АЛЛЕРГОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ALLERGOLOGY</subject></subj-group></article-categories><title-group><article-title>Бронхиальная астма и ожирение – патологический тандем: роль питания</article-title><trans-title-group xml:lang="en"><trans-title>Bronchial asthma and obesity are a pathological tandem: the role of nutrition</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трибунцева</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tribuntseva</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук </p><p>Воронеж</p></bio><bio xml:lang="en"><p>Voronezh</p></bio><email xlink:type="simple">tribunzewa@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бурлачук</surname><given-names>В. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Burlachuk</surname><given-names>V. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор </p><p>Воронеж</p></bio><bio xml:lang="en"><p>Voronezh</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Раскина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Raskina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Воронеж</p></bio><bio xml:lang="en"><p>Voronezh</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кожевникова</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozhevnikova</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук </p><p>Воронеж</p></bio><bio xml:lang="en"><p>Voronezh</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Воронежский ГМУ им. Н. Н. Бурденко Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Voronezh State Medical University named after N. N. Burdenko</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>19</day><month>07</month><year>2021</year></pub-date><volume>0</volume><issue>4</issue><fpage>7</fpage><lpage>11</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Трибунцева Л.В., Бурлачук В.Т., Раскина Е.А., Кожевникова С.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Трибунцева Л.В., Бурлачук В.Т., Раскина Е.А., Кожевникова С.А.</copyright-holder><copyright-holder xml:lang="en">Tribuntseva L.V., Burlachuk V.T., Raskina E.A., Kozhevnikova S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.lvrach.ru/jour/article/view/729">https://journal.lvrach.ru/jour/article/view/729</self-uri><abstract><p>В последнее время все чаще изучается влияние неправильного питания на возникновение и прогрессирование бронхиальной астмы (БА) и ожирения. Ожирение представляет собой пандемию XXI века. В настоящий момент имеются данные о влиянии ожирения на риск развития БА. Повышенное потребление насыщенных жиров приводит к увеличению содержания циркулирующих свободных жирных кислот в организме. Это индуцирует провоспалительные процессы в том числе в дыхательных путях, что приводит к ухудшению функционирования легких, утяжелению протекания БА, учащению обострений данного заболевания, увеличению числа госпитализаций по поводу тяжести течения астмы. Кроме того, учеными выявлено, что диета с низким содержанием пищевых волокон также способствует развитию системного воспаления, тем самым ухудшая течение БА. Имеются данные о влиянии дефицита витамина D на развитие, прогрессирование и ухудшение контроля хронических и аутоиммунных заболеваний, к которым также относится БА, на ухудшение состояния липидного обмена исследуемых. Повышение уровня витамина D в организме пациентов приводит к улучшению отдельных характеристик течения и проявления данных заболеваний. Использование средиземноморской диеты уменьшает вероятность возникновения и прогрессирования БА, бронхиальной обструкции, аллергических реакций. Достаточное употребление витаминов А, С, Е приводит к снижению воспалительных реакций в бронхиальном дереве, улучшению показателей функции легких, уменьшению обострений БА и частоты госпитализаций, связанных с ухудшением контроля заболевания. Таким образом, актуально и целесообразно проводить научную и клиническую работу по определению и более глубокому изучению влияния питания на развитие и течение БА и ожирения, выявлению взаимосвязи между данными заболеваниями.</p></abstract><trans-abstract xml:lang="en"><p>Recently, the influence of malnutrition on the occurrence and progression of bronchial asthma and obesityhas been increasingly studied. Obesity is a 21st century pandemic. Now, there is evidence of the effect of obesity on the risk of developing bronchial asthma. An increased intake of saturated fat leads to an increase in circulating free fatty acids in the body. This induces pro-inflammatory processes, including in the respiratory tract, which leads to a deterioration in the functioning of the lungs, an aggravation of the course of bronchial asthma, an increase in exacerbations of this disease, an increase in the number of hospitalizations due to the severity of the course of asthma. In addition, scientists have found that a diet low in dietary fiber also contributes to the development of systemic inflammation, thereby worsening the course of bronchial asthma. There is evidence of the effect of vitamin D deficiency on the development, progression and deterioration of control of chronic and autoimmune diseases, which also include bronchial asthma, on the deterioration of the state of lipid metabolism in the subjects. An increase in the level of vitamin D in the body of patients leads to an improvement in certain characteristics of the course and manifestation of these diseases. The use of a Mediterranean diet reduces the likelihood and progression of bronchial asthma, bronchial obstruction, and allergic reactions. Adequate intake of vitamins A, C, E leads to a decrease in inflammatory reactions in the bronchial tree, an improvement in lung function indicators, a decrease in exacerbations of bronchial asthma and the frequency of hospitalizations associated with a deterioration in the control of this pathology. Thus, it is relevant and expedient to carry out scientific and clinical work to determine and in-depth study of the influence of nutrition on the development and course of obesity and bronchial asthma, and to identify the relationship between these diseases.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>бронхиальная астма</kwd><kwd>бронхиальная обструкция</kwd><kwd>диета</kwd><kwd>высококалорийная пища</kwd><kwd>жирные кислоты</kwd><kwd>средиземноморская диета</kwd><kwd>витамины А</kwd><kwd>С</kwd><kwd>D</kwd><kwd>Е</kwd><kwd>патогенетические механизмы</kwd><kwd>воспалительные процессы</kwd><kwd>цитокины</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>bronchial asthma</kwd><kwd>diet</kwd><kwd>high-calorie food</kwd><kwd>fatty acids</kwd><kwd>Mediterranean diet</kwd><kwd>vitamins A</kwd><kwd>C</kwd><kwd>D</kwd><kwd>E</kwd><kwd>pathogenetic mechanisms</kwd><kwd>inflammatory processes</kwd><kwd>cytokines</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Finucane M. 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