lvrachЛечащий ВрачLechaschi Vrach1560-51752687-1181ООО «Издательство "Открытые системы"»lvrach-650Research ArticleСтатьиХондропения в авангарде эпидемии остеоартрита: от старения суставов к клиническому манифесту болезниChondropenia followed by epidemic of osteoarthritis: from joint aging to the clinical manifestationsНаумовА. В.NaumovA. V.nanton78@gmail.comХовасоваН. О.HovasovaN. O.noemail@neicon.ruТкачеваО. Н.TkachevaO. N.noemail@neicon.ruФГБОУ ВО РНИМУ им. Н. И. Пирогова МЗ РФRussian Federation2018230620210126969Copyright © Наумов А.В., Ховасова Н.О., Ткачева О.Н., 20212021Наумов А.В., Ховасова Н.О., Ткачева О.Н.Naumov A.V., Hovasova N.O., Tkacheva O.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.lvrach.ru/jour/article/view/650

Остеоартрит (ОА) — наиболее распространенное и социально значимое заболевание костно-мышечной системы. В основе ОА лежит системное воспаление, выработка провоспалительных цитокинов, что в свою очередь обусловливает поддержание болевого синдрома и деградации хряща. Сегодня активно развивается теория хондропении вследствие возрастного снижения гликозаминогликанов. Современная комплексная терапия ОА должна включать гликозаминогликаны.

Osteoarthritis (OA) is the most wide-spread and socially significant disease of musculoskeletal system. Systemic inflammation and formation of proinflammatory cytokines underlie OA, which, in its turn, conditions keeping pain syndrome and cartilage degradation. Currently, theory of chondropenia, due to age-related reduction of glycosaminoglycans, is actively developed. Modern complex OA therapy should include glycosaminoglycans. 

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The authors declare that there are no conflicts of interest present.