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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">lvrach</journal-id><journal-title-group><journal-title xml:lang="ru">Лечащий Врач</journal-title><trans-title-group xml:lang="en"><trans-title>Lechaschi Vrach</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-5175</issn><issn pub-type="epub">2687-1181</issn><publisher><publisher-name>ООО «Издательство "Открытые системы"»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">lvrach-541</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Сравнение вариабельности массы миокарда левого желудочка по данным эхокардиографии, традиционной и усредненной электрокардиографии в аспекте оценки эф</article-title><trans-title-group xml:lang="en"><trans-title>Comparison of the left ventricle mass variability calculated from echocardiography, traditional and averaged electrocardiography in the evaluation of the effectiveness of antihypertensive therapy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенкин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenkin</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">asemyonkin@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чиндарева</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Chindareva</surname><given-names>O. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Махрова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Makhrova</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нечаева</surname><given-names>Г. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Nechaeva</surname><given-names>G. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Потапов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Potapov</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Живилова</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhivilova</surname><given-names>L. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сивков</surname><given-names>И. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Sivkov</surname><given-names>I. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenova</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБОУ ВО ОмГМУ МЗ РФ</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>ФГБУЗ ЗСМЦ ФМБА России</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>ООО «Информационные Системы Сервиса Арт»</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>23</day><month>06</month><year>2021</year></pub-date><volume>0</volume><issue>7</issue><fpage>15</fpage><lpage>15</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Семенкин А.А., Чиндарева О.И., Махрова Н.В., Нечаева Г.И., Потапов В.В., Живилова Л.А., Сивков И.Е., Семенова Е.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Семенкин А.А., Чиндарева О.И., Махрова Н.В., Нечаева Г.И., Потапов В.В., Живилова Л.А., Сивков И.Е., Семенова Е.В.</copyright-holder><copyright-holder xml:lang="en">Semenkin A.A., Chindareva O.I., Makhrova N.V., Nechaeva G.I., Potapov V.V., Zhivilova L.A., Sivkov I.E., Semenova E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.lvrach.ru/jour/article/view/541">https://journal.lvrach.ru/jour/article/view/541</self-uri><abstract><p>Проведено сравнение вариабельности массы миокарда левого желудочка сердца (ММЛЖ), рассчитанной по данным ЭхоКГ, неусредненной и усредненной ЭКГ, и дана оценка эффективности этих методов в выявлении динамики ММЛЖ на фоне антигипертензивной терапии у больных артериальной гипертензией. Показано, что способ определения ММЛЖ по данным усредненной ЭКГ значительно превышает традиционный метод ЭКГ и ЭхоКГ по воспроизводимости, что при использовании его в клинической практике может обеспечить надежность индивидуализированной оценки изменений миокарда как при одномоментном исследовании, так и при их оценке в динамике. Использование метода в исследованиях с ЭКГ-контролем позволит сократить размер выборок или время для достижения статистически значимого результата.</p></abstract><trans-abstract xml:lang="en"><p>The comparison of the variability of left ventricular mass (LVM) calculated from echocardiography, conventional and signalaveraged ECG and evaluation the effectiveness of these methods in the detection of the LVM changes during antihypertensive therapy were performed. It was found that the reproducibility of the signal-averaged ECG method of LVM calculation is significantly higher than the conventional one and echocardiography. The use of this method in clinical practice can provide reliability of individualized assessment of LVM changes on single examination and during follow-up. The use of signal-averaged ECG may reduce groups size or the study duration to achieve statistically significant difference in studies with ECG control. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>Симпозиум</kwd><kwd>Кардиология</kwd><kwd>Ангиология</kwd><kwd>Вариабельность массы миокарда левого желудочка</kwd><kwd>Усредненная ЭКГ</kwd><kwd>Антигипертензивная терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>left ventricle mass variability</kwd><kwd>averaged ECG</kwd><kwd>antihypertensive therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Verdecchia P., Carini G., Circo A. et al. Left ventricular mass and cardiovascular morbidity in essential hypertension: the MAVI study // J Am Coll Cardiol. 2001. V. 38. № 7. Р. 1829–1835.</mixed-citation><mixed-citation xml:lang="en">Verdecchia P., Carini G., Circo A. et al. Left ventricular mass and cardiovascular morbidity in essential hypertension: the MAVI study // J Am Coll Cardiol. 2001. V. 38. № 7. Р. 1829–1835.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Angeli F., Reboldi G., Poltronieri C. et al. The prognostic legacy of left ventricular hypertrophy: cumulative evidence after the MAVI study // J Hypertens. 2015. V. 33. № 11. P. 2322–2330.</mixed-citation><mixed-citation xml:lang="en">Angeli F., Reboldi G., Poltronieri C. et al. The prognostic legacy of left ventricular hypertrophy: cumulative evidence after the MAVI study // J Hypertens. 2015. V. 33. № 11. P. 2322–2330.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Devereux R. B., Wachtell K., Gerdts E. et al. Prognostic significance of left ventricular mass change during treatment of hypertension // JAMA. 2004. V. 292. № 19. P. 2350–2356.</mixed-citation><mixed-citation xml:lang="en">Devereux R. B., Wachtell K., Gerdts E. et al. Prognostic significance of left ventricular mass change during treatment of hypertension // JAMA. 2004. V. 292. № 19. P. 2350–2356.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Devereux B., Koren M., de Simone G. et al. Methods for detection of left ventricular hypertrophy: application to hypertensive heart disease // Eur Heart J. 1993. V. 14. P. 8–15.</mixed-citation><mixed-citation xml:lang="en">Devereux B., Koren M., de Simone G. et al. Methods for detection of left ventricular hypertrophy: application to hypertensive heart disease // Eur Heart J. 1993. V. 14. P. 8–15.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Devereux R. Is ECG still useful for detection of the left ventricular hypertropy? // Circulation. 1990. V. 81. P. 1144–1146.</mixed-citation><mixed-citation xml:lang="en">Devereux R. Is ECG still useful for detection of the left ventricular hypertropy? // Circulation. 1990. V. 81. P. 1144–1146.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">De Vries S., Heesen W., Beltman F. et al. Prediction of the left ventricular mass from the electrocardiogram in systemic hypertension // Am J Cardiol. 1996. V. 77. № 11. Р. 974–978.</mixed-citation><mixed-citation xml:lang="en">De Vries S., Heesen W., Beltman F. et al. Prediction of the left ventricular mass from the electrocardiogram in systemic hypertension // Am J Cardiol. 1996. V. 77. № 11. Р. 974–978.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Wolf H., Burggraf G., Cuddy E. et al. Prediction of left ventricular mass from the electrocardiogram // J Electrocardiol. 1991. V. 24. P. 121–127.</mixed-citation><mixed-citation xml:lang="en">Wolf H., Burggraf G., Cuddy E. et al. Prediction of left ventricular mass from the electrocardiogram // J Electrocardiol. 1991. V. 24. P. 121–127.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Семенкин А. А., Чиндарева О. И., Махрова Н. В. и др. Определение массы миокарда левого желудочка по показателям усредненной электрокардиограммы // Сердечная недостаточность. 2016. Т. 17. № 5. С. 333–338.</mixed-citation><mixed-citation xml:lang="en">Семенкин А. А., Чиндарева О. И., Махрова Н. В. и др. Определение массы миокарда левого желудочка по показателям усредненной электрокардиограммы // Сердечная недостаточность. 2016. Т. 17. № 5. С. 333–338.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Lang R. M., Badano L. P., Mor-Avi V. et al. Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging // Journal of the American Society of Echocardiography. 2015. V. 28. № 1. Р. 1–35.</mixed-citation><mixed-citation xml:lang="en">Lang R. M., Badano L. P., Mor-Avi V. et al. Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging // Journal of the American Society of Echocardiography. 2015. V. 28. № 1. Р. 1–35.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Семенкин А. А., Сивков И. Е., Лебедев В. М., Миллер Т. С. Свидетельство о Государственной регистрации программы для ЭВМ «ECG HR» № 2011616724 (RU); 29.08.2011.</mixed-citation><mixed-citation xml:lang="en">Семенкин А. А., Сивков И. Е., Лебедев В. М., Миллер Т. С. Свидетельство о Государственной регистрации программы для ЭВМ «ECG HR» № 2011616724 (RU); 29.08.2011.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Семенкин А. А., Чиндарева О. И., Махрова Н. В., Нечаева Г. И., Потапов В. В., Живилова Л. А., Семенова Е. В. Способ определения массы миокарда левого желудочка сердца у больных неосложненной артериальной гипертензией при помощи усредненной электрокардиографии. Пат. 2015151297, (RU); ГБОУ ВПО ОмГМУ Минздрава Росии (RU). № 2612822; заявл. 30.11.15; опубл. 13.03.17, Бюл. № 8.</mixed-citation><mixed-citation xml:lang="en">Семенкин А. А., Чиндарева О. И., Махрова Н. В., Нечаева Г. И., Потапов В. В., Живилова Л. А., Семенова Е. В. Способ определения массы миокарда левого желудочка сердца у больных неосложненной артериальной гипертензией при помощи усредненной электрокардиографии. Пат. 2015151297, (RU); ГБОУ ВПО ОмГМУ Минздрава Росии (RU). № 2612822; заявл. 30.11.15; опубл. 13.03.17, Бюл. № 8.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Bland J., Altman D. Statistical methods for assessing agreement between two measures of clinical measurement // Lancet. 1986. V. 1 (8476). Р. 307–310.</mixed-citation><mixed-citation xml:lang="en">Bland J., Altman D. Statistical methods for assessing agreement between two measures of clinical measurement // Lancet. 1986. V. 1 (8476). Р. 307–310.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Петри А., Сэбин К. Наглядная статистика в медицине. М.: Гэотар-Мед. 2003. С. 87–89.</mixed-citation><mixed-citation xml:lang="en">Петри А., Сэбин К. Наглядная статистика в медицине. М.: Гэотар-Мед. 2003. С. 87–89.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Collins H., Kronenberg M., Byrd B. Reproducibility of left ventricular mass measurements by two-dimensional and M-mode echocardiography // J Am Coll Cardiol. 1989. V. 14. № 3. H. 672–676.</mixed-citation><mixed-citation xml:lang="en">Collins H., Kronenberg M., Byrd B. Reproducibility of left ventricular mass measurements by two-dimensional and M-mode echocardiography // J Am Coll Cardiol. 1989. V. 14. № 3. H. 672–676.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Himelman R., Cassidy M., Landzberg J., Schiller N. Reproducibility of quantitative two-dimensional echocardiography // Am Heart J. 1988. V. 115. № 2. Р. 425–431.</mixed-citation><mixed-citation xml:lang="en">Himelman R., Cassidy M., Landzberg J., Schiller N. Reproducibility of quantitative two-dimensional echocardiography // Am Heart J. 1988. V. 115. № 2. Р. 425–431.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Palmieri V., Dahl?f B., De Quattro V. et al. Reliability of echocardiographic assessment of left ventricular structure and function: the PRESERVE study. Prospective Randomized Study Evaluating Regression of Ventricular Enlargement // J Am Coll Cardiol. 1999. V. № 34 (5). Р. 1625–1632.</mixed-citation><mixed-citation xml:lang="en">Palmieri V., Dahl?f B., De Quattro V. et al. Reliability of echocardiographic assessment of left ventricular structure and function: the PRESERVE study. Prospective Randomized Study Evaluating Regression of Ventricular Enlargement // J Am Coll Cardiol. 1999. V. № 34 (5). Р. 1625–1632.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Agabiti-Rosei E., Ambrosioni E., Finardi G. et al. Perindopril versus captopril: efficacy and acceptability in an italian multicenter trial // Am J Med. 1992. № 92 (4 B). Р. 79–83.</mixed-citation><mixed-citation xml:lang="en">Agabiti-Rosei E., Ambrosioni E., Finardi G. et al. Perindopril versus captopril: efficacy and acceptability in an italian multicenter trial // Am J Med. 1992. № 92 (4 B). Р. 79–83.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Graettinger W., Lipson J., Klein R. et al. Comparison of antihypertensive therapies by noninvasive techniques // Chest. 1989. V. 96. P. 74–79.</mixed-citation><mixed-citation xml:lang="en">Graettinger W., Lipson J., Klein R. et al. Comparison of antihypertensive therapies by noninvasive techniques // Chest. 1989. V. 96. P. 74–79.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Devereux R., Palmieri V., Sharpe N. et al. Effects of once-daily angiotensin-converting enzyme inhibition and calcium channel blockade–based antihypertensive treatment regimens on left ventricular hypertrophy and diastolic filling in hypertension the prospective randomized enalapril study evaluating regression of ventricular enlargement (PRESERVE) trial // Circulation. 2001. V. 104. P. 1248–1254.</mixed-citation><mixed-citation xml:lang="en">Devereux R., Palmieri V., Sharpe N. et al. Effects of once-daily angiotensin-converting enzyme inhibition and calcium channel blockade–based antihypertensive treatment regimens on left ventricular hypertrophy and diastolic filling in hypertension the prospective randomized enalapril study evaluating regression of ventricular enlargement (PRESERVE) trial // Circulation. 2001. V. 104. P. 1248–1254.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Koldas L., Ayan F., Ikitimur B. Short term effects of rilmenidine on left ventricular hypertrophy and systolic and diastolic function in patients with essential hypertension comparison with an angiotensin converting enzyme inhibitor and a calcium antagonist // Jpn Heart J. 2003. V. 44. V. 693–704.</mixed-citation><mixed-citation xml:lang="en">Koldas L., Ayan F., Ikitimur B. Short term effects of rilmenidine on left ventricular hypertrophy and systolic and diastolic function in patients with essential hypertension comparison with an angiotensin converting enzyme inhibitor and a calcium antagonist // Jpn Heart J. 2003. V. 44. V. 693–704.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Matsuzaki K., Mukai M., Sumimoto T., Murakami E. Effects of ace inhibitors versus calcium antagonists on left ventricular morphology and function in patients with essential hypertension // Hypertens Res. 1997. V. 20. P. 7–10.</mixed-citation><mixed-citation xml:lang="en">Matsuzaki K., Mukai M., Sumimoto T., Murakami E. Effects of ace inhibitors versus calcium antagonists on left ventricular morphology and function in patients with essential hypertension // Hypertens Res. 1997. V. 20. P. 7–10.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Moroni C., Tolone S., Lopreiato F. et al. Effects of losartan on left ventricular mass: a three-year follow-up in elderly hypertensives with myocardial hypertrophy despite successful conventional antihypertensive treatment // European Review for Medical and Pharmacological Sciences. 2017. V. 21. P. 1323–1328.</mixed-citation><mixed-citation xml:lang="en">Moroni C., Tolone S., Lopreiato F. et al. Effects of losartan on left ventricular mass: a three-year follow-up in elderly hypertensives with myocardial hypertrophy despite successful conventional antihypertensive treatment // European Review for Medical and Pharmacological Sciences. 2017. V. 21. P. 1323–1328.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Rakic D., Rumboldt Z., Bagatin J., Polic S. Effects of four antihypertensive monotherapies on cardiac mass and function in hypertensive patients with left ventricular hypertrophy: randomized prospective study // Croat Med J. 2002. V. 43. P. 672–679.</mixed-citation><mixed-citation xml:lang="en">Rakic D., Rumboldt Z., Bagatin J., Polic S. Effects of four antihypertensive monotherapies on cardiac mass and function in hypertensive patients with left ventricular hypertrophy: randomized prospective study // Croat Med J. 2002. V. 43. P. 672–679.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Roman M., Alderman M., Pickering T. et al. Differential effects of angiotensin converting enzyme inhibition and diuretic therapy on reductions in ambulatory blood pressure, left ventricular mass, and vascular hypertrophy // Am J Hypertens. 1998. V. 11 (4 Pt 1). P. 387–396.</mixed-citation><mixed-citation xml:lang="en">Roman M., Alderman M., Pickering T. et al. Differential effects of angiotensin converting enzyme inhibition and diuretic therapy on reductions in ambulatory blood pressure, left ventricular mass, and vascular hypertrophy // Am J Hypertens. 1998. V. 11 (4 Pt 1). P. 387–396.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Cuspidi C., Sala С., Negri F. et al. Prevalence of left-ventricular hypertrophy in hypertension: an updated review of echocardiographic studies // Journal of Human Hypertension. 2012. V. 26. P. 343–349.</mixed-citation><mixed-citation xml:lang="en">Cuspidi C., Sala С., Negri F. et al. Prevalence of left-ventricular hypertrophy in hypertension: an updated review of echocardiographic studies // Journal of Human Hypertension. 2012. V. 26. P. 343–349.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Cuspidi C., Rescaldanic M., Sala C. et al. Prevalence of electrocardiographic left ventricular hypertrophy in human hypertension: an updated review // Journal of Hypertension. 2012. V. 30. P. 2066–2073.</mixed-citation><mixed-citation xml:lang="en">Cuspidi C., Rescaldanic M., Sala C. et al. Prevalence of electrocardiographic left ventricular hypertrophy in human hypertension: an updated review // Journal of Hypertension. 2012. V. 30. P. 2066–2073.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
