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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">lvrach</journal-id><journal-title-group><journal-title xml:lang="ru">Лечащий Врач</journal-title><trans-title-group xml:lang="en"><trans-title>Lechaschi Vrach</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-5175</issn><issn pub-type="epub">2687-1181</issn><publisher><publisher-name>ООО «Издательство "Открытые системы"»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">lvrach-478</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Многоликий ринит: современный взгляд на диагностику и алгоритм лечения</article-title><trans-title-group xml:lang="en"><trans-title>Мany-sided rhinitis: current approach to diagnosis and treatment algorithm</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Астафьева</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Astafieva</surname><given-names>N. G.</given-names></name></name-alternatives><email xlink:type="simple">astang@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кобзев</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kobzev</surname><given-names>D. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гамова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gamova</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Перфилова</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Perfilova</surname><given-names>I. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Удовиченко</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Udovichenko</surname><given-names>E. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скучаева</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Skuchaeva</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлова</surname><given-names>И. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Michailova</surname><given-names>I. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ГБОУ ВПО СГМУ им. В. И. Разумовского МЗ РФ</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Лидс Тринити университет</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>23</day><month>06</month><year>2021</year></pub-date><volume>0</volume><issue>4</issue><fpage>7</fpage><lpage>7</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Астафьева Н.Г., Кобзев Д.Ю., Гамова И.В., Перфилова И.А., Удовиченко Е.Н., Скучаева Л.В., Михайлова И.Э., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Астафьева Н.Г., Кобзев Д.Ю., Гамова И.В., Перфилова И.А., Удовиченко Е.Н., Скучаева Л.В., Михайлова И.Э.</copyright-holder><copyright-holder xml:lang="en">Astafieva N.G., Kobzev D.Y., Gamova I.V., Perfilova I.A., Udovichenko E.N., Skuchaeva L.V., Michailova I.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.lvrach.ru/jour/article/view/478">https://journal.lvrach.ru/jour/article/view/478</self-uri><abstract><p>Риниты относятся к широко распространенным заболеваниям и нередко являются начальным ключевым звеном в формировании респираторной патологии как верхних, так и нижних дыхательных путей. В данном обзоре представлена информация о важности аналитического подхода к определению факторов риска, фенотипической классификации, критериям диагноза и терапии неаллергического ринита.</p></abstract><trans-abstract xml:lang="en"><p>Rhinitis is one of the most common diseases and is often the initial key link in the formation of respiratory pathology of both upper and lower respiratory tract. This review provides information on importance of analytical approach to identifying risk factors, phenotypic classification, criteria for diagnosis and therapy of non-allergic rhinitis. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>Симпозиум</kwd><kwd>Аллергология</kwd><kwd>Иммунология</kwd><kwd>Неаллергический ринит</kwd><kwd>Диагноз</kwd><kwd>Дифференциальный диагноз</kwd><kwd>Лечение</kwd><kwd>Интраназальные кортикостероиды</kwd><kwd>Антилейкотриены</kwd><kwd>Интраназальные антигистаминные препараты</kwd><kwd>Оральные антигистаминные препараты</kwd><kwd>Таргетная терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>non-allergic rhinitis</kwd><kwd>diagnosis</kwd><kwd>differential diagnosis</kwd><kwd>treatment</kwd><kwd>intranasal corticosteroids</kwd><kwd>leucotriene antagonist</kwd><kwd>intranasal antihistamines</kwd><kwd>oral antihistamines</kwd><kwd>targeted therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA (2)LEN and AllerGen) // Allergy. 2008; 63, Suppl. 86: 8–160.</mixed-citation><mixed-citation xml:lang="en">Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA (2)LEN and AllerGen) // Allergy. 2008; 63, Suppl. 86: 8–160.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Brozek J. 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