<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">lvrach</journal-id><journal-title-group><journal-title xml:lang="ru">Лечащий Врач</journal-title><trans-title-group xml:lang="en"><trans-title>Lechaschi Vrach</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-5175</issn><issn pub-type="epub">2687-1181</issn><publisher><publisher-name></publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26295/0S.2019.15.45.006</article-id><article-id custom-type="elpub" pub-id-type="custom">lvrach-278</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Вопросы первичной профилактики инсульта у взрослых и детей</article-title><trans-title-group xml:lang="en"><trans-title>Prevention of primary stroke in adults and children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Визило</surname><given-names>Т. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Vizilo</surname><given-names>T. L.</given-names></name></name-alternatives><email xlink:type="simple">vizilo@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попонникова</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Poponnikova</surname><given-names>T. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федосеева</surname><given-names>И. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedoseeva</surname><given-names>I. F.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБОУ ВО КемГМУ МЗ РФ</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>23</day><month>06</month><year>2021</year></pub-date><volume>0</volume><issue>10</issue><fpage>30</fpage><lpage>35</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Визило Т.Л., Попонникова Т.В., Федосеева И.Ф., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Визило Т.Л., Попонникова Т.В., Федосеева И.Ф.</copyright-holder><copyright-holder xml:lang="en">Vizilo T.L., Poponnikova T.V., Fedoseeva I.F.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.lvrach.ru/jour/article/view/278">https://journal.lvrach.ru/jour/article/view/278</self-uri><abstract><p>В статье отражены современные представления о профилактике инсульта. Проанализированы общепризнанные стратегии профилактики инсульта и предложены новые подходы к профилактике нарушений мозгового кровообращения.</p></abstract><trans-abstract xml:lang="en"><p>Modern views of stroke prevention are discussed. Universally recognized strategies of stroke prevention are analyzed and new approaches to preventive treatment of cerebral circulation disorders are proposed. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>Артериальная гипертензия</kwd><kwd>Инсульт</kwd><kwd>Кардиоэмболия</kwd><kwd>Коллоквиум</kwd><kwd>Профилактика инсульта</kwd><kwd>Психоневрология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>stroke</kwd><kwd>stroke prevention</kwd><kwd>arterial hypertension</kwd><kwd>cardioembolism</kwd><kwd>atherothrombosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Feigin V. L., Norrving B., Mensah G. A. Global burden of stroke // Circ Res. 2017; 120 (03) 439-448.</mixed-citation><mixed-citation xml:lang="en">Feigin V. L., Norrving B., Mensah G. A. Global burden of stroke // Circ Res. 2017; 120 (03) 439-448.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Суслина З. А., Варакин Ю. Я. Клиническое руководство по ранней диагностике, лечению и профилактике сосудистых заболеваний головного мозга. М.: МЕДпресс-информ, 2015. 440 с.</mixed-citation><mixed-citation xml:lang="en">Суслина З. А., Варакин Ю. Я. Клиническое руководство по ранней диагностике, лечению и профилактике сосудистых заболеваний головного мозга. М.: МЕДпресс-информ, 2015. 440 с.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Фейгин В. Л., Варакин Ю. Я., Кравченко М. А., Пирадов М. А., Танашян И. И., Гнедовская Е. В., Стаховская Л. В., Шамалов Н. А., Кришнамурти Р. и др. Новый подход к профилактике инсульта в России // Анналы клинической и экспериментальной неврологии. 2015. Т. 9, № 4.</mixed-citation><mixed-citation xml:lang="en">Фейгин В. Л., Варакин Ю. Я., Кравченко М. А., Пирадов М. А., Танашян И. И., Гнедовская Е. В., Стаховская Л. В., Шамалов Н. А., Кришнамурти Р. и др. Новый подход к профилактике инсульта в России // Анналы клинической и экспериментальной неврологии. 2015. Т. 9, № 4.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Association of Smoking Cessation With Subsequent Risk of Cardiovascular Disease // JAMA. 2019, Aug 20; 322 (7): 642-650. DOI: 10.1001/jama.2019.10298.</mixed-citation><mixed-citation xml:lang="en">Association of Smoking Cessation With Subsequent Risk of Cardiovascular Disease // JAMA. 2019, Aug 20; 322 (7): 642-650. DOI: 10.1001/jama.2019.10298.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines // J Am Coll Cardiol. 2019; March 17: [Epub ahead of print].</mixed-citation><mixed-citation xml:lang="en">ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines // J Am Coll Cardiol. 2019; March 17: [Epub ahead of print].</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Rippe J. M. Lifestyle Medicine 2019: Deeper, Broader, and More Precise. // Am J Lifestyle Med. 2019, Sep-Oct; 13 (5): 436-439. Epub 2019 May 22.</mixed-citation><mixed-citation xml:lang="en">Rippe J. M. Lifestyle Medicine 2019: Deeper, Broader, and More Precise. // Am J Lifestyle Med. 2019, Sep-Oct; 13 (5): 436-439. Epub 2019 May 22.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Eckel R. H., Jakicic J. M., Ard J. D., de Jesus J. M., Houston Miller N., Hubbard V. S. et al. 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines // Circulation 2014; 129 (25 Suppl 2): S76-S99.</mixed-citation><mixed-citation xml:lang="en">Eckel R. H., Jakicic J. M., Ard J. D., de Jesus J. M., Houston Miller N., Hubbard V. S. et al. 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines // Circulation 2014; 129 (25 Suppl 2): S76-S99.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Estruch R., Ros E., Salas-Salvad? J., Covas M. I., Corella D., Ar?s F. et al. Primary prevention of cardiovascular disease with a Mediterranean diet // N Engl J Med. 2013; 368: 1279-1290.</mixed-citation><mixed-citation xml:lang="en">Estruch R., Ros E., Salas-Salvad? J., Covas M. I., Corella D., Ar?s F. et al. Primary prevention of cardiovascular disease with a Mediterranean diet // N Engl J Med. 2013; 368: 1279-1290.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Sarkkinen E. S., Kastarinen M. J., Niskanen T. H., Karjalainen P. H., Ven?l?inen T. M., Udani J. K. et al. Feasibility and antihypertensive effect of replacing regular salt with mineral salt - rich in magnesium and potassium - in subjects with mildly elevated blood pressure // Nutr J. 2011; 10: 88.</mixed-citation><mixed-citation xml:lang="en">Sarkkinen E. S., Kastarinen M. J., Niskanen T. H., Karjalainen P. H., Ven?l?inen T. M., Udani J. K. et al. Feasibility and antihypertensive effect of replacing regular salt with mineral salt - rich in magnesium and potassium - in subjects with mildly elevated blood pressure // Nutr J. 2011; 10: 88.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Strazzullo P., D’Elia L., Cairella G., Garbagnati F., Cappuccio F. P., Scalfi L. Excess body weight and incidence of stroke: metaanalysis of prospective studies with 2 million participants // Stroke. 2010; 41: e418-e426.</mixed-citation><mixed-citation xml:lang="en">Strazzullo P., D’Elia L., Cairella G., Garbagnati F., Cappuccio F. P., Scalfi L. Excess body weight and incidence of stroke: metaanalysis of prospective studies with 2 million participants // Stroke. 2010; 41: e418-e426.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Prospective Studies Collaboration, Whitlock G., Lewington S., Sherliker P., Clarke R., Emberson J. et al. Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies // Lancet. 2009; 373: 1083-1096.</mixed-citation><mixed-citation xml:lang="en">Prospective Studies Collaboration, Whitlock G., Lewington S., Sherliker P., Clarke R., Emberson J. et al. Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies // Lancet. 2009; 373: 1083-1096.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Whelton P. K., Carey R. M., Aronow W. S., Casey D. E. Jr., Collins K. J., Dennison Himmelfarb C. et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on clinical practice guidelines // Hypertension. 2018; 71: 1269-1324.</mixed-citation><mixed-citation xml:lang="en">Whelton P. K., Carey R. M., Aronow W. S., Casey D. E. Jr., Collins K. J., Dennison Himmelfarb C. et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on clinical practice guidelines // Hypertension. 2018; 71: 1269-1324.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Garber A. J., Abrahamson M. J., Barzilay J. I., Blonde L., Bloomgarden Z. T., Bush M. A. et al. Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm: 2018 executive summary // Endocr Pract. 2018; 24: 91-120.</mixed-citation><mixed-citation xml:lang="en">Garber A. J., Abrahamson M. J., Barzilay J. I., Blonde L., Bloomgarden Z. T., Bush M. A. et al. Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm: 2018 executive summary // Endocr Pract. 2018; 24: 91-120.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Guidelines for the Primary Prevention of Stroke. A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association // Stroke. 2014; 45.</mixed-citation><mixed-citation xml:lang="en">Guidelines for the Primary Prevention of Stroke. A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association // Stroke. 2014; 45.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Prospective Studies Collaboration, Lewington S., Whitlock G., Clarke R., Sherliker P., Emberson J. et al. Blood cholesterol and vascular mortality by age, sex, and blood pressure: a metaanalysis of individual data from 61 prospective studies with 55,000 vascular deaths // Lancet. 2007; 370: 1829-1839.</mixed-citation><mixed-citation xml:lang="en">Prospective Studies Collaboration, Lewington S., Whitlock G., Clarke R., Sherliker P., Emberson J. et al. Blood cholesterol and vascular mortality by age, sex, and blood pressure: a metaanalysis of individual data from 61 prospective studies with 55,000 vascular deaths // Lancet. 2007; 370: 1829-1839.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Everett B. M., Glynn R. J., MacFadyen J. G., Ridker P. M. Rosuvastatin in the prevention of stroke among men and women with elevated levels of C-reactive protein: Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) // Circulation. 2010; 121: 143-150.</mixed-citation><mixed-citation xml:lang="en">Everett B. M., Glynn R. J., MacFadyen J. G., Ridker P. M. Rosuvastatin in the prevention of stroke among men and women with elevated levels of C-reactive protein: Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) // Circulation. 2010; 121: 143-150.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Hackam D. G., Woodward M., Newby L. K., Bhatt D. L., Shao M., Smith E. E. et al. Statins and intracerebral hemorrhage: collaborative systematic review and meta-analysis // Circulation. 2011; 124: 2233-2242.</mixed-citation><mixed-citation xml:lang="en">Hackam D. G., Woodward M., Newby L. K., Bhatt D. L., Shao M., Smith E. E. et al. Statins and intracerebral hemorrhage: collaborative systematic review and meta-analysis // Circulation. 2011; 124: 2233-2242.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Kelly P. J., Murphy S., Coveney S. et al. Anti-inflammatory approaches to ischaemic stroke prevention // Journal of Neurology, Neurosurgery &amp; Psychiatry. 2018; 89: 211-218.</mixed-citation><mixed-citation xml:lang="en">Kelly P. J., Murphy S., Coveney S. et al. Anti-inflammatory approaches to ischaemic stroke prevention // Journal of Neurology, Neurosurgery &amp; Psychiatry. 2018; 89: 211-218.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Rosales D., Garcia-Gracia C., Salgado E. et al. Primary central nervous system vasculitis triggered by cytomegalovirus encephalitis // Neurology. 2013; 80 (Supp. P01.231).</mixed-citation><mixed-citation xml:lang="en">Rosales D., Garcia-Gracia C., Salgado E. et al. Primary central nervous system vasculitis triggered by cytomegalovirus encephalitis // Neurology. 2013; 80 (Supp. P01.231).</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Субботин А. В., Семенов В. А., Этенко Д. А., Мошнигуц С. В., Гуревич И. Н. Редкий случай острого ишемического инсульта в результате сифилитического склерозирующего поражения сонных артерий // Фундаментальная и клиническая медицина. 2017. Т. 2. № 1. С. 121-126.</mixed-citation><mixed-citation xml:lang="en">Субботин А. В., Семенов В. А., Этенко Д. А., Мошнигуц С. В., Гуревич И. Н. Редкий случай острого ишемического инсульта в результате сифилитического склерозирующего поражения сонных артерий // Фундаментальная и клиническая медицина. 2017. Т. 2. № 1. С. 121-126.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Tsivgoulis G., Katsanos A. H., Giannopoulos G., Panagopoulou V., Jatuzis D., Lemmens R. et al. The role of colchicine in the prevention of cerebrovascular ischemia // Curr Pharm Des. 2018; 24: 668-674.</mixed-citation><mixed-citation xml:lang="en">Tsivgoulis G., Katsanos A. H., Giannopoulos G., Panagopoulou V., Jatuzis D., Lemmens R. et al. The role of colchicine in the prevention of cerebrovascular ischemia // Curr Pharm Des. 2018; 24: 668-674.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Jenny N. S., Callas P. W., Judd S. E., McClure L. A., Kissela B., Zakai N. A., Cushman M. Inflammatory cytokines and ischemic stroke risk // Neurology. 2019, May, 92 (20), e2375-e2384.</mixed-citation><mixed-citation xml:lang="en">Jenny N. S., Callas P. W., Judd S. E., McClure L. A., Kissela B., Zakai N. A., Cushman M. Inflammatory cytokines and ischemic stroke risk // Neurology. 2019, May, 92 (20), e2375-e2384.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Carlton C., Banks M., Sundararajan S. Oral Contraceptives and Ischemic Stroke Risk // Originally published 16 Mar 2018. https://doi.org/10.1161/STROKEAHA.117.020084. Stroke. 2018; 49: e157-e159.</mixed-citation><mixed-citation xml:lang="en">Carlton C., Banks M., Sundararajan S. Oral Contraceptives and Ischemic Stroke Risk // Originally published 16 Mar 2018. https://doi.org/10.1161/STROKEAHA.117.020084. Stroke. 2018; 49: e157-e159.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Carrasquilla G. D., Frumento P., Berglund A. et al. Postmenopausal hormone therapy and risk of stroke: A pooled analysis of data from population-based cohort studies // PLoS Med. 2017; 14: e1002445.</mixed-citation><mixed-citation xml:lang="en">Carrasquilla G. D., Frumento P., Berglund A. et al. Postmenopausal hormone therapy and risk of stroke: A pooled analysis of data from population-based cohort studies // PLoS Med. 2017; 14: e1002445.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">The NAMS2017 Hormone Therapy Position Statement Advisory Panel. The 2017 hormone therapy position statement of The North American Menopause Society // Menopause. 2017; 24: 728-753.</mixed-citation><mixed-citation xml:lang="en">The NAMS2017 Hormone Therapy Position Statement Advisory Panel. The 2017 hormone therapy position statement of The North American Menopause Society // Menopause. 2017; 24: 728-753.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Chang C. C., Chuang H. C., Lin C. L. et al. High incidence of stroke in young women with sleep apnea syndrome // Sleep Med. 2014; 15: 410-414.</mixed-citation><mixed-citation xml:lang="en">Chang C. C., Chuang H. C., Lin C. L. et al. High incidence of stroke in young women with sleep apnea syndrome // Sleep Med. 2014; 15: 410-414.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Leng Y., Cappuccio F. P., Wainwright N. W. et al. Sleep duration and risk of fatal and non-fatal stroke: a prospective study and meta-analysis // Neurology. 2015; 84: 1072-1079.</mixed-citation><mixed-citation xml:lang="en">Leng Y., Cappuccio F. P., Wainwright N. W. et al. Sleep duration and risk of fatal and non-fatal stroke: a prospective study and meta-analysis // Neurology. 2015; 84: 1072-1079.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Hsu C. Y., Chen Y. T., Chen M. H. et al. The association between insomnia and increased future cardiovascular events: a nation-wide population-based study // Psychosom Med. 2015; 77: 743-751.</mixed-citation><mixed-citation xml:lang="en">Hsu C. Y., Chen Y. T., Chen M. H. et al. The association between insomnia and increased future cardiovascular events: a nation-wide population-based study // Psychosom Med. 2015; 77: 743-751.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">De Veber G. The epidemiology of childhood stroke. In: Stroke and cerebrovascular disease in childhood. Eds. V. Ganesan, F. Kirkham, London: Mac Keith Press; 2011; 22-26.</mixed-citation><mixed-citation xml:lang="en">De Veber G. The epidemiology of childhood stroke. In: Stroke and cerebrovascular disease in childhood. Eds. V. Ganesan, F. Kirkham, London: Mac Keith Press; 2011; 22-26.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Rivkin M. J., Bernard T. J., Dowling M. M., Amlie-Lefond C. Guidelines for Urgent Management of Stroke in Children // Pediatr Neurol. 2016; 56: 8-17. DOI: 10.1016/j.pediatrneurol.2016.01.016.</mixed-citation><mixed-citation xml:lang="en">Rivkin M. J., Bernard T. J., Dowling M. M., Amlie-Lefond C. Guidelines for Urgent Management of Stroke in Children // Pediatr Neurol. 2016; 56: 8-17. DOI: 10.1016/j.pediatrneurol.2016.01.016.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Heron M. Deaths: leading causes for 2010 // Natl Vital Stat Rep. 2013; 62: 1-96. The link is active on: 04.07.16. Available at: http://www.cdc.gov/nchs/data/nvsr/nvsr62/nvsr62_06.pdf.</mixed-citation><mixed-citation xml:lang="en">Heron M. Deaths: leading causes for 2010 // Natl Vital Stat Rep. 2013; 62: 1-96. The link is active on: 04.07.16. Available at: http://www.cdc.gov/nchs/data/nvsr/nvsr62/nvsr62_06.pdf.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Щугарева Л. М., Лазебник Т. А., Андрущенко Н. В., Потешкина О. В. и др. Инсульты у детей. СПб: СпецЛит, 2019. 40 с.</mixed-citation><mixed-citation xml:lang="en">Щугарева Л. М., Лазебник Т. А., Андрущенко Н. В., Потешкина О. В. и др. Инсульты у детей. СПб: СпецЛит, 2019. 40 с.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Roach E. S., Golomb M. R., Adams R., Biller J., Daniels S., De Veber G., Ferriero D., Jones B. V., Kirkham F. J., Scott R. M., Smith E. R. Management of Stroke in Infants and Children: A Scientific Statement From a Special Writing Group of the American Heart Association Stroke Council and the Council on Cardiovascular Disease in the Young // Stroke. 2008; 39: 2644-2691. DOI: 10.1161/STROKEAHA.108.189696.</mixed-citation><mixed-citation xml:lang="en">Roach E. S., Golomb M. R., Adams R., Biller J., Daniels S., De Veber G., Ferriero D., Jones B. V., Kirkham F. J., Scott R. M., Smith E. R. Management of Stroke in Infants and Children: A Scientific Statement From a Special Writing Group of the American Heart Association Stroke Council and the Council on Cardiovascular Disease in the Young // Stroke. 2008; 39: 2644-2691. DOI: 10.1161/STROKEAHA.108.189696.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Jordan L. C., Hillis A. E. Challenges in the diagnosis and treatment of pediatric stroke // Nat Rev Neurol. 2011; 7 (4): 199-208. DOI: 10.1038/nrneurol.2011.23.</mixed-citation><mixed-citation xml:lang="en">Jordan L. C., Hillis A. E. Challenges in the diagnosis and treatment of pediatric stroke // Nat Rev Neurol. 2011; 7 (4): 199-208. DOI: 10.1038/nrneurol.2011.23.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Щедеркина И. О., Заваденко Н. Н., Колтунов И. Е. Инсульт у детей и подростков: формирование педиатрического регистра // Журнал неврологии и психиатрии. 2016; 116 (9): 24-9.</mixed-citation><mixed-citation xml:lang="en">Щедеркина И. О., Заваденко Н. Н., Колтунов И. Е. Инсульт у детей и подростков: формирование педиатрического регистра // Журнал неврологии и психиатрии. 2016; 116 (9): 24-9.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Launthier S., Carmant L., David M. et al. Stroke in children: The coexistence of multiple risk factors predicts poor outcome // Neurology. 2000; 54: 371-378.</mixed-citation><mixed-citation xml:lang="en">Launthier S., Carmant L., David M. et al. Stroke in children: The coexistence of multiple risk factors predicts poor outcome // Neurology. 2000; 54: 371-378.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Зыков В. П., Комарова И. Б., Ушакова Л. В. Ишемический инсульт у детей // Российский медицинский журнал. 2008; 6: 27-31.</mixed-citation><mixed-citation xml:lang="en">Зыков В. П., Комарова И. Б., Ушакова Л. В. Ишемический инсульт у детей // Российский медицинский журнал. 2008; 6: 27-31.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Management of Stroke in Neonates and Children: A Scientific Statement From the American Heart Association/American Stroke Association. Donna M. Ferriero, Heather J. Fullerton, Timothy J. Bernard, at all., and on behalf of the American Heart Association Stroke Council and Council on Cardiovascular and Stroke Nursing // Originally published 28 Jan 2019 https://doi.org/10.1161/STR.0000000000000183. Stroke. 2019; 50: e51-e96.</mixed-citation><mixed-citation xml:lang="en">Management of Stroke in Neonates and Children: A Scientific Statement From the American Heart Association/American Stroke Association. Donna M. Ferriero, Heather J. Fullerton, Timothy J. Bernard, at all., and on behalf of the American Heart Association Stroke Council and Council on Cardiovascular and Stroke Nursing // Originally published 28 Jan 2019 https://doi.org/10.1161/STR.0000000000000183. Stroke. 2019; 50: e51-e96.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Recent Advances in Primary and Secondary Prevention of Atherosclerotic Stroke // J Stroke. 2018; 20 (2): 145-166. Published online May 31, 2018. DOI: https: //doi.org/10.5853/jos.2018.00773.</mixed-citation><mixed-citation xml:lang="en">Recent Advances in Primary and Secondary Prevention of Atherosclerotic Stroke // J Stroke. 2018; 20 (2): 145-166. Published online May 31, 2018. DOI: https: //doi.org/10.5853/jos.2018.00773.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
