<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">lvrach</journal-id><journal-title-group><journal-title xml:lang="ru">Лечащий Врач</journal-title><trans-title-group xml:lang="en"><trans-title>Lechaschi Vrach</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-5175</issn><issn pub-type="epub">2687-1181</issn><publisher><publisher-name></publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26295/OS.2019.36.68.004</article-id><article-id custom-type="elpub" pub-id-type="custom">lvrach-259</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Сложности и ошибки диагностики первичного сифилиса в проктологической практике (разбор клинических случаев)</article-title><trans-title-group xml:lang="en"><trans-title>Difficulties and errors in the diagnosis of primary syphilis in proctological practice (analysis of clinical cases)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Левчик</surname><given-names>Н. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Levchik</surname><given-names>N. K.</given-names></name></name-alternatives><email xlink:type="simple">nklevchik@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сурганова</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Surganova</surname><given-names>V. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зильберберг</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zilberberg</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пономарева</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ponomareva</surname><given-names>M. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ГБУ СО УрНИИДВиИ</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>23</day><month>06</month><year>2021</year></pub-date><volume>0</volume><issue>11</issue><fpage>16</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Левчик Н.К., Сурганова В.И., Зильберберг Н.В., Пономарева М.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Левчик Н.К., Сурганова В.И., Зильберберг Н.В., Пономарева М.В.</copyright-holder><copyright-holder xml:lang="en">Levchik N.K., Surganova V.I., Zilberberg N.V., Ponomareva M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.lvrach.ru/jour/article/view/259">https://journal.lvrach.ru/jour/article/view/259</self-uri><abstract><p>Мы сообщаем о трех случаях первичного сифилиса, впервые диагностированного как новообразование прямой кишки и парапроктит, и описываем клинические и лабораторные особенности заболеваний. Обсуждаются проблемы диагностики первичного сифилиса. Специалисты должны знать о возможности сифилиса при аноректальной патологии, чтобы избежать неправильного диагноза, ненадлежащего лечения и отсроченной антибактериальной терапии, и собирать подробную информацию о сексуальных предпочтениях, включая гомосексуальность.</p></abstract><trans-abstract xml:lang="en"><p>We report three cases of primary syphilis firstly diagnosed as rectal neoplasma and paraproctitis and describe the clinical and laboratory features of the diseases. Diagnostic problems of primary syphilis are discussed. Specialists should be aware of the possibility of syphilis when confronted with anorectal pathology in order to avoid incorrect diagnosis, inappropriate treatment, and delayed antibiotic therapy, and should gather a detailed history about sexual preferences, including homosexuality. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>HIV</kwd><kwd>ВИЧ</kwd><kwd>Дерматовенерология</kwd><kwd>Мужчины</kwd><kwd>практикующие секс с мужчинами</kwd><kwd>Новообразование прямой кишки</kwd><kwd>Ошибки диагностики</kwd><kwd>Парапроктит</kwd><kwd>Первичный сифилис</kwd><kwd>Прямые методы диагностики</kwd><kwd>Серологические тесты</kwd><kwd>Симпозиум</kwd></kwd-group><kwd-group xml:lang="en"><kwd>primary syphilis</kwd><kwd>Treponema pallidum</kwd><kwd>extragenital chancres</kwd><kwd>HIV</kwd><kwd>men who have sex with men</kwd><kwd>rectal neoplasma</kwd><kwd>paraproctitis</kwd><kwd>error diagnosis</kwd><kwd>serological tests</kwd><kwd>direct diagnostic methods</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Zhao W. T., Liu J., Li Y. Y. Syphilitic proctitis mimicking rectal cancer: a case report // World J Gastrointest Pathophysiol. 2010; 1: 112-114.</mixed-citation><mixed-citation xml:lang="en">Zhao W. T., Liu J., Li Y. Y. Syphilitic proctitis mimicking rectal cancer: a case report // World J Gastrointest Pathophysiol. 2010; 1: 112-114.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Cha J. M., Choi S., Lee J. Rectal syphilis mimicking rectal cancer // Yonsei Med J. 2010, Mar; 51 (2): 276-278.</mixed-citation><mixed-citation xml:lang="en">Cha J. M., Choi S., Lee J. Rectal syphilis mimicking rectal cancer // Yonsei Med J. 2010, Mar; 51 (2): 276-278.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Febbraro I., Manetti G., Balestrieri P., Zippi M. Rectal cancer or rectal chancre? Beware of primary syphilis // Digestive and Liver Disease. 2008, vol. 40, № 7, p. 579-581.</mixed-citation><mixed-citation xml:lang="en">Febbraro I., Manetti G., Balestrieri P., Zippi M. Rectal cancer or rectal chancre? Beware of primary syphilis // Digestive and Liver Disease. 2008, vol. 40, № 7, p. 579-581.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Song S. H., Jang I., Kim B. S. et al. A case of primary syphilis in the rectum // J Korean Med Sci. 2005; 20: 886-887.</mixed-citation><mixed-citation xml:lang="en">Song S. H., Jang I., Kim B. S. et al. A case of primary syphilis in the rectum // J Korean Med Sci. 2005; 20: 886-887.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Мавлютова Г. И., Юсупова Л. А. Ошибки диагностики сифилиса в практике врачей различных специальностей // Лечащий Врач. 2014. № 11. С. 12.</mixed-citation><mixed-citation xml:lang="en">Мавлютова Г. И., Юсупова Л. А. Ошибки диагностики сифилиса в практике врачей различных специальностей // Лечащий Врач. 2014. № 11. С. 12.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Yilmaz M., R. Memisoglu, Aydin S. et al. Anorectal syphilis mimicking Crohn’s disease // Journal of Infection and Chemotherapy. 2011, vol. 17, № 5, p. 713-715.</mixed-citation><mixed-citation xml:lang="en">Yilmaz M., R. Memisoglu, Aydin S. et al. Anorectal syphilis mimicking Crohn’s disease // Journal of Infection and Chemotherapy. 2011, vol. 17, № 5, p. 713-715.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Towns J. M., Leslie D. E., Denham I. et al. Painful and multiple anogenital lesions are common in men with Treponema pallidum PCR-positive primary syphilis without herpes simplex virus coinfection: a cross-sectional clinic-based study // Sex Transm Infect. 2016, 92: 110-115.</mixed-citation><mixed-citation xml:lang="en">Towns J. M., Leslie D. E., Denham I. et al. Painful and multiple anogenital lesions are common in men with Treponema pallidum PCR-positive primary syphilis without herpes simplex virus coinfection: a cross-sectional clinic-based study // Sex Transm Infect. 2016, 92: 110-115.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Marfin A. A., Liu H., Sutton M. Y. et al. Amplification of the DNA polymerase I gene of Treponema pallidum from whole blood of persons with syphilis // Diagn Microbiol Infect Dis. 2001, 40: 163-166.</mixed-citation><mixed-citation xml:lang="en">Marfin A. A., Liu H., Sutton M. Y. et al. Amplification of the DNA polymerase I gene of Treponema pallidum from whole blood of persons with syphilis // Diagn Microbiol Infect Dis. 2001, 40: 163-166.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Radolf J. D., Deka R. K., Anand A. et al. Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen // Nat Rev Microbiol. 2016; 14 (12): 744-759.</mixed-citation><mixed-citation xml:lang="en">Radolf J. D., Deka R. K., Anand A. et al. Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen // Nat Rev Microbiol. 2016; 14 (12): 744-759.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
