lvrachЛечащий ВрачLechaschi Vrach1560-51752687-1181ООО «Издательство "Открытые системы"»10.26295/OS.2020.75.65.001lvrach-212Research ArticleСтатьиДиета и дерматологические заболевания: аспекты профилактики и леченияDiet and dermatological diseases: aspects of prevention and treatmentОхлопковВ. А.OkhlopkovV. A.

Moscow

ЛялюковаЕ. А.LyalyukovaE. A.

Omsk

lyalykova@rambler.ruЧернышеваЕ. Н.ChernyshevaE. N.

Astrakhan

noemail@neicon.ruНадейЕ. В.NadeyE. V.

Omsk

noemail@neicon.ruЛялюковА. В.LyalukovA. V.

Sochi

noemail@neicon.ruИВДПО ФНКЦ РРРоссияInstitute of Higher and Further Professional Education FNKTs RRRussian FederationФГБОУ ВО ОмГМУ МЗ РФРоссияOmsk State Medical University of the Ministry of Health of the Russian FederationRussian FederationФГБОУ ВО Астраханский ГМУ Минздрава РоссииРоссияAstrakhan State Medical University of the Ministry of Health of the Russian FederationRussian FederationФГБОУ ВО СГУРоссияSochi State University of the Ministry of Health of the Russian FederationRussian Federation202023062021011711Copyright © Охлопков В.А., Лялюкова Е.А., Чернышева Е.Н., Надей Е.В., Лялюков А.В., 20212021Охлопков В.А., Лялюкова Е.А., Чернышева Е.Н., Надей Е.В., Лялюков А.В.Okhlopkov V.A., Lyalyukova E.A., Chernysheva E.N., Nadey E.V., Lyalukov A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.lvrach.ru/jour/article/view/212

Целью обзора явилось изучение современных литературных данных о влиянии диеты на состояние кожи и течение некоторых дерматологических заболеваний. Недавние исследования обнаружили тесную связь между диетой и рядом дерматологических заболеваний. Аллергические реакции на продукты, западный тип питания могут значительно изменять состав микробиома и проницаемость кишечника. В условиях нарушенного микробного баланса и изменения барьерной функции кишечника увеличивается проникновение в системный кровоток иммуногенных молекул, включая пищевые антигены, бактериальные токсины и патогены, которые могут накапливаться в коже, нарушать эпидермальный барьер, способствовать хроническому воспалению. Однако при атопическом дерматите у детей элиминационные диеты не показали значительного преимущества в снижении тяжести заболевания, напротив, чаще регистрировались нежелательные явления, связанные с недостаточностью питания, дефицитом витаминов и минералов. Несмотря на то, что диетические вмешательства важный аспект терапии и превентивной медицины при широком спектре дерматологических заболеваний, многие вопросы на сегодняшний день остаются открытыми.

The purpose of the review was to study the data of the modern literature on the effect of diet on the skin condition and the course of some dermatological diseases. Recent studies have shown a strong link between diet and a number of dermatological conditions. Food allergies and Western eating patterns can dramatically alter microbiome composition and intestinal permeability. In conditions of disturbed microbial balance and changes in the barrier function of the intestine, the penetration of immunogenic molecules into the systemic circulation, including food antigens, bacterial toxins and pathogens, which can accumulate in the skin, disrupt the epidermal barrier and contribute to chronic inflammation, increase. However, in children with atopic dermatitis, elimination diets did not show a significant advantage in reducing the severity of the disease; on the contrary, adverse events associated with malnutrition, lack of vitamins and minerals were more often recorded. Despite the fact that dietary intervention is an important aspect of the treatment and prevention of a wide range of dermatological diseases, many questions remain open today. 

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The authors declare that there are no conflicts of interest present.