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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">lvrach</journal-id><journal-title-group><journal-title xml:lang="ru">Лечащий Врач</journal-title><trans-title-group xml:lang="en"><trans-title>Lechaschi Vrach</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-5175</issn><issn pub-type="epub">2687-1181</issn><publisher><publisher-name></publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51793/OS.2026.29.1.009</article-id><article-id custom-type="elpub" pub-id-type="custom">lvrach-1530</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКТУАЛЬНАЯ ТЕМА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>TOPICAL THEME</subject></subj-group></article-categories><title-group><article-title>Возможности повидон-йода в местной терапии инфекционновоспалительных заболеваний урогенитального тракта</article-title><trans-title-group xml:lang="en"><trans-title>Povidone-iodine capabilities in the local therapy of urogenital infectious and inflammatory diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7407-7575</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зильберберг</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zilberberg</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зильберберг Наталья Владимировна, д.м.н., профессор, заместитель директора по научной работе</p><p>620076, Екатеринбург, ул. Щербакова, 8</p></bio><bio xml:lang="en"><p>Natalia V. Zilberberg, Dr. of Sci. (Med.), Professor, Deputy Director</p><p>8 Shcherbakova str., Yekaterinburg, 620076</p></bio><email xlink:type="simple">zilberberg@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5755-8783</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полищук</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Polishchuk</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Полищук Антон Ильич, к.м.н., старший научный сотрудник научного клинического отдела дерматологии</p><p>620076, Екатеринбург, ул. Щербакова, 8</p></bio><bio xml:lang="en"><p>Anton I. Polishchuk, Cand. of Sci. (Med.), Senior Researcher of Scientific research Department of Dermatology</p><p>8 Shcherbakova str., Yekaterinburg, 620076</p></bio><email xlink:type="simple">ai.polishchuk@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Уральский научно-исследовательский институт дерматовенерологии и иммунопатологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ural Scientific Research Institute of Dermatovenerology and Immunopathology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>22</day><month>01</month><year>2026</year></pub-date><volume>0</volume><issue>1</issue><fpage>64</fpage><lpage>68</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зильберберг Н.В., Полищук А.И., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Зильберберг Н.В., Полищук А.И.</copyright-holder><copyright-holder xml:lang="en">Zilberberg N.V., Polishchuk A.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.lvrach.ru/jour/article/view/1530">https://journal.lvrach.ru/jour/article/view/1530</self-uri><abstract><sec><title>Введение</title><p>Введение. Повидон-йод – водорастворимый препарат йода с антимикробным эффектом в отношении широкого спектра микроорганизмов (бактерий, грибов, простейших, вирусов). При этом за десятилетия применения не зафиксировано развития резистентности микроорганизмов к повидон-йоду благодаря множественным мишеням его действия. Повидон-йод длительно применяется в хирургической, гинекологической и дерматологической практике, высокоэффективен в ряде различных лекарственных форм и концентраций, сохраняет свою антимикробную активность вплоть до разведений в 100 раз и более. Ввиду высокого профиля безопасности растворов с более низкой концентрацией при сохранении их эффективности, низкоконцентрированные растворы повидон-йода могут использоваться в том числе на коже и слизистых мочеполовой системы, что позволяет рассматривать такие растворы как перспективное дополнение к основной терапии (а в ряде случаев и как вариант основной терапии) бактериального вагиноза и инфекций, передающихся половым путем.</p></sec><sec><title>Заключение</title><p>Заключение. Зарегистрированная в РФ линейка препаратов в форме мази и раствора, содержащая 10,0% и 7,5% повидон-йода соответственно, обладает заявленным противомикробным эффектом и показана для использования в дерматовенерологии. В Государственном бюджетном учреждении Свердловской области «Уральский научно-исследовательский институт дерматовенерологии и иммунопатологии» планируется исследование, посвященное использованию раствора повидон-йода при инфекционно-воспалительных заболеваниях гениталий в дополнение к показанному при этом диагнозе системному лечению в соответствии с действующими клиническими рекомендациями.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Povidone-iodine is a water – soluble iodine formulation with antimicrobial effect against a wide range of microorganisms (bacteria, fungi, protozoa, viruses). No acquired microbial resistance has been reported for povidone-iodine over the decades of its use due to its multiple-targeted action. Povidone-iodine has been used for a long time in surgical, gynecological and dermatological practice; it is highly effective in different forms and concentrations and retains its antimicrobial activity even when diluted 1:100 or more. Due to the high safety profile of lower concentration povidone-iodine solutions (while maintaining their effectiveness), they can also be used on the skin and mucous membranes of the genitourinary system, so these solutions may be considered as a promising addition to the main therapy (or in some cases as a variant of the main therapy) of bacterial vaginosis or sexually transmitted infections.</p></sec><sec><title>Conclusion</title><p>Conclusion. The range of povidone-iodine formulations is registered in the Russian Federation in the form of a 10.0% ointment and a 7.5% solution; it has a declared antimicrobial effect and is indicated for use in dermatovenereology. Ural Scientific Research Institute of Dermatovenerology and Immunopathology has scheduled a study of using povidone-iodine solution in patients with urogenital infectious and inflammatory diseases in addition to the systemic treatment indicated for these diagnoses in accordance with current guidelines.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>повидон-йод</kwd><kwd>бактериальный вагиноз</kwd><kwd>топическая терапия</kwd><kwd>антимикробное действие</kwd></kwd-group><kwd-group xml:lang="en"><kwd>povidone-iodine</kwd><kwd>bacterial vaginosis</kwd><kwd>topical therapy</kwd><kwd>antimicrobial action</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lepelletier D., Maillard J. Y., Pozzetto B., et al. Povidone Iodine: Properties, Mechanisms of Action, and Role in Infection Control and Staphylococcus aureus Decolonization. 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