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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">lvrach</journal-id><journal-title-group><journal-title xml:lang="ru">Лечащий Врач</journal-title><trans-title-group xml:lang="en"><trans-title>Lechaschi Vrach</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-5175</issn><issn pub-type="epub">2687-1181</issn><publisher><publisher-name></publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51793/OS.2023.26.12.006</article-id><article-id custom-type="elpub" pub-id-type="custom">lvrach-1164</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СТРАНИЧКА ПЕДИАТРА. В помощь врачу-практику</subject></subj-group></article-categories><title-group><article-title>Гастроинтестинальная аллергия: алгоритмы для амбулаторного педиатра</article-title><trans-title-group xml:lang="en"><trans-title>A pediatrician's guide to gastrointestinal allergies</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-5735-9562</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Конобейцев</surname><given-names>О. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Konobeitsev</surname><given-names>O. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Конобейцев Олег Хананович, гастроэнтеролог</p><p>620109, Екатеринбург, ул. Заводская, 29</p></bio><bio xml:lang="en"><p>Oleg Kh. Konobeitsev, gastroenterologist</p><p>29 Zavodskaya str., Yekaterinburg, 620109</p></bio><email xlink:type="simple">konobeitsev@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Общество с ограниченной ответственностью «Медицинское объединение «Новая больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Limited Liability Company «Medical Association «New Hospital»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>21</day><month>01</month><year>2024</year></pub-date><volume>0</volume><issue>12</issue><fpage>45</fpage><lpage>49</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Конобейцев О.Х., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Конобейцев О.Х.</copyright-holder><copyright-holder xml:lang="en">Konobeitsev O.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.lvrach.ru/jour/article/view/1164">https://journal.lvrach.ru/jour/article/view/1164</self-uri><abstract><sec><title>Введение</title><p>Введение. Аллергия на коровье молоко является одной из наиболее распространенных пищевых аллергий у детей. Гастроинтестинальные формы пищевой аллергии требуют особого внимания амбулаторного педиатра, но остаются по-прежнему плохо распознаваемыми. В основном гастроинтестинальные формы пищевой аллергии встречаются у детей первых лет жизни и часто имеют неспецифические признаки – беспокойное поведение, изменения паттернов стула или срыгиваний, что ведет к ошибочной трактовке клинических симптомов. Постановка диагноза затрудняется отсроченным появлением симптомов по причине не-IgE-опосредованного типа аллергической реакции в большинстве случаев и, соответственно, отсутствия информативности при классическом подходе к диагностике аллергии. Две наиболее частые формы гастроинтестинальной пищевой аллергии, встречающиеся в практике педиатра: аллергический проктоколит, характерный для первых месяцев жизни и имеющий самый благоприятный прогноз, и синдром энтероколита в ответ на пищевые белки, часто встречающийся во втором полугодии на фоне введения прикормов. Они не требуют специализированных методов диагностики в условиях стационара. Элиминационная диета является основным инструментом для диагностики и диетотерапии аллергического компонента данных состояний.</p></sec><sec><title>Цель работы</title><p>Цель работы. Предоставить клинический алгоритм для амбулаторного педиатра по тактике ведения детей с не-IgE-опосредованной гастроинтестинальной пищевой аллергией.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Cow's milk allergy is one of the most common food allergies in children. Gastrointestinal forms of food allergy require special attention from the pediatrician, but they still remain poorly recognized. Mostly, gastrointestinal forms of food allergies occur in children of the first years of life, and often have nonspecific signs – restless behavior, changes in stool patterns or regurgitation, which leads to an erroneous interpretation of clinical symptoms. The diagnosis is complicated by the delayed onset of symptoms due to the non-IgE-mediated type of allergic reaction in most cases, therefore, the lack of information content in the classical approach to diagnosing allergies. The two most common forms of gastrointestinal food allergies encountered in pediatric practice: allergic proctocolitis (FPIAP), characteristic of the first months of life and having the most favorable prognosis, and food protein enterocolitis syndrome (FPIES), often occurring in the second half of the year, against the background of the introduction of complementary foods. They do not require specialized diagnostic methods in a hospital setting. The elimination diet is the main tool for diagnosis and dietary therapy of these allergic conditions.</p></sec><sec><title>Objective</title><p>Objective. To provide a clinical algorithm for outpatient pediatricians on the management of children with non-IgE-mediated gastrointestinal food allergy.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>аллергология</kwd><kwd>белки коровьего молока</kwd><kwd>гастроэнтерология</kwd><kwd>диагностика</kwd><kwd>не-IgE-опосредованная аллергия</kwd><kwd>диетотерапия</kwd><kwd>нутрициология</kwd><kwd>педиатрия</kwd><kwd>пищевая аллергия</kwd><kwd>проктоколит</kwd><kwd>энтероколит</kwd><kwd>энтеропатия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>allergology</kwd><kwd>cow's milk proteins</kwd><kwd>gastroenterology</kwd><kwd>diagnostics</kwd><kwd>dietary therapy</kwd><kwd>non-IgE-mediated</kwd><kwd>nutrition science</kwd><kwd>pediatric</kwd><kwd>food allergy</kwd><kwd>proctocolitis</kwd><kwd>enterocolitis</kwd><kwd>enteropathy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Meyer R., Chebar Lozinsky A., Fleischer D. 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