<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">lvrach</journal-id><journal-title-group><journal-title xml:lang="ru">Лечащий Врач</journal-title><trans-title-group xml:lang="en"><trans-title>Lechaschi Vrach</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-5175</issn><issn pub-type="epub">2687-1181</issn><publisher><publisher-name></publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51793/OS.2023.26.3.003</article-id><article-id custom-type="elpub" pub-id-type="custom">lvrach-1031</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КАРДИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>Иглорефлексотерапия в лечении и реабилитации пациентов с ишемическим инсультом</article-title><trans-title-group xml:lang="en"><trans-title>Acupuncture in the treatment and rehabilitation of patients with ischemic stroke</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0632-6653</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юсупов</surname><given-names>Ф. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yusupov</surname><given-names>F. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юсупов Фуркат Абдулахатович, доктор медицинских наук, профессор, заведующий кафедрой неврологии, психиатрии и нейрохирургии медицинского факультета </p><p>723500, Кыргызстан, Ош, ул. Ленина, 331</p></bio><bio xml:lang="en"><p>Furhat A. Yusupov, Dr. of Sci. (Med.), Professor, Head of the Department of Neurology, Psychiatry and Neurosurgery of the Medical Faculty </p><p>331 Lenin Street, Osh, 723500, Kyrgyzstan; </p></bio><email xlink:type="simple">furcat_y@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4179-9205</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юлдашев</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yuldashev</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Акмал Акбарович, аспирант кафедры неврологии, психиатрии и нейрохирургии медицинского факультета </p><p>723500, Кыргызстан, Ош, ул. Ленина, 331</p></bio><bio xml:lang="en"><p>Akmal A. Yuldashev, PhD student of the Department of Neurology, Psychiatry and Neurosurgery </p><p>331 Lenin Street, Osh, 723500, Kyrgyzstan</p></bio><email xlink:type="simple">akmal.yuldashev.2017@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ошский государственный университет</institution><country>Кыргызстан</country></aff><aff xml:lang="en"><institution>Osh State University</institution><country>Kyrgyzstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>13</day><month>04</month><year>2023</year></pub-date><volume>0</volume><issue>3</issue><fpage>18</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Юсупов Ф.А., Юлдашев А.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Юсупов Ф.А., Юлдашев А.А.</copyright-holder><copyright-holder xml:lang="en">Yusupov F.A., Yuldashev A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.lvrach.ru/jour/article/view/1031">https://journal.lvrach.ru/jour/article/view/1031</self-uri><abstract><p>Острое нарушение мозгового кровообращения было и остается одной из лидирующих причин заболеваемости, инвалидности и смертности населения в мире. Мозговые инсульты не только медицинская, но и большая социально-экономическая проблема для государства. Наиболее частые неврологические нарушения, вызванные инсультом, включают расстройства когнитивной, двигательной и чувствительной функций. Пациенты, перенесшие инфаркт миокарда, примерно в 90% случаев могут возвращаться к прежней работе. Что касается инсульта, то ситуация здесь совершенно иная: всего лишь 10-20% выживших способны продолжать прежнюю работу в облегченном режиме, а остальные 80-90% остаются инвалидами с разной степенью ограничения трудоспособности. Поэтому лечение и ранняя реабилитация пациентов с инсультом остаются в центре внимания клиницистов. Наряду с медикаментозной терапией, иглорефлексотерапия повышает лечебный и реабилитационный потенциал больных ишемическим инсультом, улучшая нейро-, ангиои синаптогенез в зоне ишемии. Иглоукалывание рекомендовано Всемирной организацией здравоохранения в качестве альтернативной и дополнительной стратегии лечения инсульта и улучшения его исходов. В обзоре раскрыты механизмы лечебного и восстановительного влияния иглорефлексотерапии при ишемических инсультах.</p></abstract><trans-abstract xml:lang="en"><p>Acute cerebrovascular accident has been and remains one of the leading causes of morbidity, disability and mortality in the world. Brain strokes are not only medical, but also a big socio-economic problem for the state. The most common neurological disorders caused by stroke include impaired cognitive, motor and sensory function. Patients who have suffered a myocardial infarction about 90% can return to their previous jobs as for stroke, the situation is completely different from the survivors, only about 10-20% can continue their previous work in a light mode, and the remaining 70-80% remain disabled with varying degrees of disability. Therefore, treatment and early rehabilitation remains the focus of clinicians' attention. Along with drug therapy, acupuncture increases the therapeutic and rehabilitation potential of patients with ischemic stroke as it improves neurogenesis, angiogenesis, synaptogenesis in the ischemic area. Acupuncture is recommended by the World Health Organization (WHO) as an alternative and complementary strategy for treating stroke and improving the outcome of strokes. The review reveals the mechanisms of therapeutic and restorative effects of acupuncture in ischemic strokes. K</p></trans-abstract><kwd-group xml:lang="ru"><kwd>острое нарушение мозгового кровообращения</kwd><kwd>ишемический инсульт</kwd><kwd>иглорефлексотерапия</kwd><kwd>акупунктура</kwd><kwd>лечение</kwd><kwd>реабилитация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute cerebrovascular accident</kwd><kwd>ischemic stroke</kwd><kwd>acupuncture</kwd><kwd>treatment</kwd><kwd>rehabilitation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Writing Group Members. Mozaffarian D., Benjamin E. J., Go A. S., Arnett D. K., Blaha M. J., Cushman M., Das S. R., de Ferranti S., Després J. P., et al. Heart disease and stroke statistics-2016 update: A report from the American Heart Association // Circulation. 2016; 133: e38-e360. DOI: 10.1161/CIR.0000000000000350.</mixed-citation><mixed-citation xml:lang="en">Writing Group Members. Mozaffarian D., Benjamin E. J., Go A. S., Arnett D. K., Blaha M. J., Cushman M., Das S. R., de Ferranti S., Després J. P., et al. Heart disease and stroke statistics-2016 update: A report from the American Heart Association // Circulation. 2016; 133: e38-e360. DOI: 10.1161/CIR.0000000000000350.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Krishnamurthi R. V., Feigin V. L., Forouzanfar M. H., Mensah G. A., Connor M., Bennett D. A., Moran A. E., Sacco R. L., Anderson L. M., Truelsen T., et al. Global and regional burden of first-ever ischaemic and haemorrhagic stroke during 1990-2010: Findings from the Global Burden of Disease Study 2010 // Health. 2013; 1: e259-e281. DOI: 10.1016/S2214-109X(13)70089-5.</mixed-citation><mixed-citation xml:lang="en">Krishnamurthi R. V., Feigin V. L., Forouzanfar M. H., Mensah G. A., Connor M., Bennett D. A., Moran A. E., Sacco R. L., Anderson L. M., Truelsen T., et al. Global and regional burden of first-ever ischaemic and haemorrhagic stroke during 1990-2010: Findings from the Global Burden of Disease Study 2010 // Health. 2013; 1: e259-e281. DOI: 10.1016/S2214-109X(13)70089-5.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Chavez L. M., Huang S. S., MacDonald I., Lin J. G., Lee Y. C., Chen Y. H. Mechanisms of Acupuncture Therapy in Ischemic Stroke Rehabilitation: A Literature Review of Basic Studies // International journal of molecular sciences, 2017; 18 (11): 2270. https://doi.org/10.3390/ijms18112270.</mixed-citation><mixed-citation xml:lang="en">Chavez L. M., Huang S. S., MacDonald I., Lin J. G., Lee Y. C., Chen Y. H. Mechanisms of Acupuncture Therapy in Ischemic Stroke Rehabilitation: A Literature Review of Basic Studies // International journal of molecular sciences, 2017; 18 (11): 2270. https://doi.org/10.3390/ijms18112270.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kornienko V. N., Pronin I. N. Diagnostic Neuroradiology. Springer; Berlin, Germany: 2009.</mixed-citation><mixed-citation xml:lang="en">Kornienko V. N., Pronin I. N. Diagnostic Neuroradiology. Springer; Berlin, Germany: 2009.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Deb P., Sharma S., Hassan K. M. Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis // Pathophysiology. 2010; 17: 197-218. DOI: 10.1016/j.pathophys.2009.12.001.</mixed-citation><mixed-citation xml:lang="en">Deb P., Sharma S., Hassan K. M. Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis // Pathophysiology. 2010; 17: 197-218. DOI: 10.1016/j.pathophys.2009.12.001.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Doyle K. P., Simon R. P., Stenzel-Poore M. P. Mechanisms of ischemic brain damage // Neuropharmacology. 2008; 55: 310-318. DOI: 10.1016/j.neuropharm.2008.01.005.</mixed-citation><mixed-citation xml:lang="en">Doyle K. P., Simon R. P., Stenzel-Poore M. P. Mechanisms of ischemic brain damage // Neuropharmacology. 2008; 55: 310-318. DOI: 10.1016/j.neuropharm.2008.01.005.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Brouns R., de Deyn P. P. The complexity of neurobiological processes in acute ischemic stroke // Clin. Neurol. Neurosurg. 2009; 111: 483-495. DOI: 10.1016/j.clineuro.2009.04.001.</mixed-citation><mixed-citation xml:lang="en">Brouns R., de Deyn P. P. The complexity of neurobiological processes in acute ischemic stroke // Clin. Neurol. Neurosurg. 2009; 111: 483-495. DOI: 10.1016/j.clineuro.2009.04.001.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Felling R. J., Song H. Epigenetic mechanisms of neuroplasticity and the implications for stroke recovery // Exp. Neurol. 2015; 268: 37-45. DOI: 10.1016/j.expneurol.2014.09.017.</mixed-citation><mixed-citation xml:lang="en">Felling R. J., Song H. Epigenetic mechanisms of neuroplasticity and the implications for stroke recovery // Exp. Neurol. 2015; 268: 37-45. DOI: 10.1016/j.expneurol.2014.09.017.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Smith W. S., Johnston S. C., Hemphill J. C., III. Cerebrovascular diseases. In: Kasper D., Fauci A., Hauser S., Longo D., Jameson J., Loscalzo J., editors. Harrison’s Principles of Internal Medicine. 19th ed. Volume 2. Mc Graw Hill Education; New York, NY, USA: 2014.</mixed-citation><mixed-citation xml:lang="en">Smith W. S., Johnston S. C., Hemphill J. C., III. Cerebrovascular diseases. In: Kasper D., Fauci A., Hauser S., Longo D., Jameson J., Loscalzo J., editors. Harrison’s Principles of Internal Medicine. 19th ed. Volume 2. Mc Graw Hill Education; New York, NY, USA: 2014.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Intercollegiate Stroke Working Party. National Clinical Guideline for Stroke. 4th ed. Royal College of Physicians; London, UK: 2012.</mixed-citation><mixed-citation xml:lang="en">Intercollegiate Stroke Working Party. National Clinical Guideline for Stroke. 4th ed. Royal College of Physicians; London, UK: 2012.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Brainin M., Zorowitz R. D. Advances in stroke: Recovery and rehabilitation // Stroke. 2013; 44: 311-313. DOI: 10.1161/STROKEAHA.111.000342.</mixed-citation><mixed-citation xml:lang="en">Brainin M., Zorowitz R. D. Advances in stroke: Recovery and rehabilitation // Stroke. 2013; 44: 311-313. DOI: 10.1161/STROKEAHA.111.000342.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Li X., Wang Q. Acupuncture therapy for stroke patients // Int. Rev. Neurobiol. 2013; 111: 159-179. DOI: 10.1016/B978-0-12-411545-3.00008-0.</mixed-citation><mixed-citation xml:lang="en">Li X., Wang Q. Acupuncture therapy for stroke patients // Int. Rev. Neurobiol. 2013; 111: 159-179. DOI: 10.1016/B978-0-12-411545-3.00008-0.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Li A. H., Zhang J. M., Xie Y. K. Human acupuncture points mapped in rats are associated with excitable muscle/skin-nerve complexes with enriched nerve endings // Brain Res. 2004; 1012: 154-159. DOI: 10.1016/j.brainres.2004.04.009.</mixed-citation><mixed-citation xml:lang="en">Li A. H., Zhang J. M., Xie Y. K. Human acupuncture points mapped in rats are associated with excitable muscle/skin-nerve complexes with enriched nerve endings // Brain Res. 2004; 1012: 154-159. DOI: 10.1016/j.brainres.2004.04.009.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Zhao Z. Q. Neural mechanism underlying acupuncture analgesia // Prog. Neurobiol. 2008; 85: 355-375. DOI: 10.1016/j.pneurobio.2008.05.004.</mixed-citation><mixed-citation xml:lang="en">Zhao Z. Q. Neural mechanism underlying acupuncture analgesia // Prog. Neurobiol. 2008; 85: 355-375. DOI: 10.1016/j.pneurobio.2008.05.004.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Manni L., Albanesi M., Guaragna M., Barbaro Paparo S., Aloe L. Neurotrophins and acupuncture // Auton. Neurosci. 2010; 157: 9-17. DOI: 10.1016/j.autneu.2010.03.020.</mixed-citation><mixed-citation xml:lang="en">Manni L., Albanesi M., Guaragna M., Barbaro Paparo S., Aloe L. Neurotrophins and acupuncture // Auton. Neurosci. 2010; 157: 9-17. DOI: 10.1016/j.autneu.2010.03.020.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Na B. J., Jahng G. H., Park S. U., Jung W. S., Moon S. K., Park J. M., Bae H. S. An fMRI study of neuronal specificity of an acupoint: Electroacupuncture stimulation of Yanglingquan (GB34) and its sham point // Neurosci. Lett. 2009; 464: 1-5. DOI: 10.1016/j.neulet.2009.08.009.</mixed-citation><mixed-citation xml:lang="en">Na B. J., Jahng G. H., Park S. U., Jung W. S., Moon S. K., Park J. M., Bae H. S. An fMRI study of neuronal specificity of an acupoint: Electroacupuncture stimulation of Yanglingquan (GB34) and its sham point // Neurosci. Lett. 2009; 464: 1-5. DOI: 10.1016/j.neulet.2009.08.009.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Wu Z., Hu J., Du F., Zhou X., Xiang Q., Miao F. Long-term changes of diffusion tensor imaging and behavioural status after acupuncture treatment in rats with transient focal cerebral ischaemia // Acup. Med. 2012; 30: 331-338. DOI: 10.1136/acupmed-2012-010172.</mixed-citation><mixed-citation xml:lang="en">Wu Z., Hu J., Du F., Zhou X., Xiang Q., Miao F. Long-term changes of diffusion tensor imaging and behavioural status after acupuncture treatment in rats with transient focal cerebral ischaemia // Acup. Med. 2012; 30: 331-338. DOI: 10.1136/acupmed-2012-010172.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Liu S. Y., Hsieh C. L., Wei T. S., Liu P. T., Chang Y. J., Li T. C. Acupuncture stimulation improves balance function in stroke patients: A single-blinded controlled, randomized study // Am. J. Chin. Med. 2009; 7: 483-494. DOI: 10.1142/S0192415X09006990.</mixed-citation><mixed-citation xml:lang="en">Liu S. Y., Hsieh C. L., Wei T. S., Liu P. T., Chang Y. J., Li T. C. Acupuncture stimulation improves balance function in stroke patients: A single-blinded controlled, randomized study // Am. J. Chin. Med. 2009; 7: 483-494. DOI: 10.1142/S0192415X09006990.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
