lvrachЛечащий ВрачLechaschi Vrach1560-51752687-118110.26295/OS.2020.85.98.001lvrach-103Research ArticleСтатьиРоль пробиотиков в формировании микробиоты кишечника у детейRole of pribiotics for intestinal microbiota formation in childrenГрибакинС. Г.GribakinS. G.serg.gribakin2016@yandex.ruФГБОУ ДПО РМАНПО МЗ РФRussian Federation2020230620210477Copyright © Грибакин С.Г., 20212021Грибакин С.Г.Gribakin S.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.lvrach.ru/jour/article/view/103

Кишечная микробиота (КМ) играет ключевую роль в процессах ферментации олигосахаридов, в модуляции иммунитета и в защите от условно-патогенных микроорганизмов. Колонизация пищеварительного тракта новорожденного начинается с участия вагинальной флоры матери и продолжается благодаря участию олигосахаридов грудного молока. Как бифидобактерии, так и лактобациллы являются наиболее распространенными представителями КМ и оказывают различные физиологические эффекты. Новое комбинированное пробиотическое средство содержит штаммы B. breve BR-03 и L. rhamnosus GG. Обсуждаются показания и клинические аспекты его назначения.

Intestinal microbiota (IM) plays a key role in colonic fermentation of oligosaccharides, in immunity modulation and in protection against conventionally pathogenic microorganisms. Colonization of gastrointestinal tract in newborns starts with participation of the mother’s vaginal flora and continuous due to breast feeding by means of breast milk oligosaccharides. Both bifidobacteria and lactobacilli are the most common representatives of IM with a number of physiologic effects. The new combined probiotic contains B. breve BR-03 and L. rhamnosus GG strains. Indications and other clinical aspects are discussed. 

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The authors declare that there are no conflicts of interest present.