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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">lvrach</journal-id><journal-title-group><journal-title xml:lang="ru">Лечащий Врач</journal-title><trans-title-group xml:lang="en"><trans-title>Lechaschi Vrach</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-5175</issn><issn pub-type="epub">2687-1181</issn><publisher><publisher-name></publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51793/OS.2022.25.12.012</article-id><article-id custom-type="elpub" pub-id-type="custom">lvrach-1008</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКТУАЛЬНАЯ ТЕМА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>TOPICAL THEME</subject></subj-group></article-categories><title-group><article-title>Эффективность нутритивной поддержки при комплексном восстановительном лечении пациентов, перенесших COVID-19</article-title><trans-title-group xml:lang="en"><trans-title>The effectiveness of nutritional support in the complex rehabilitation treatment of patients after COVID-19</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2392-3134</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зуйкова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zuikova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зуйкова Анна Александровна, д.м.н., профессор, заведующая кафедрой поликлинической терапии</p><p>394036, Воронеж, ул. Студенческая, 10</p></bio><bio xml:lang="en"><p>Anna A. Zuikova, Dr. of Sci. (Med.), Professor, Head of the Department of Polyclinic Therapy</p><p>10 Studentskaya Str., Voronezh, 394036</p></bio><email xlink:type="simple">zuikova-terapia23@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4763-4153</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бугримов</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Bugrimov</surname><given-names>D. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бугримов Даниил Юрьевич, к.м.н., доцент кафедры патологической анатомии</p><p>394036, Воронеж, ул. Студенческая, 10</p></bio><bio xml:lang="en"><p>Daniil Yu. Bugrimov, MD, Associate Professor of the Department of Pathological Anatomy</p><p>10 Studentskaya Str., Voronezh, 394036</p></bio><email xlink:type="simple">danikst@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4796-7334</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Красноруцкая</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Krasnorutskaya</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Красноруцкая Ольга Николаевна, д.м.н., профессор кафедры поликлинической терапии</p><p>394036, Воронеж, ул. Студенческая, 10</p></bio><bio xml:lang="en"><p>Olga N. Krasnorutskaya, Dr. of Sci. (Med.), Professor of the Department of Polyclinic Therapy</p><p>10 Studentskaya Str., Voronezh, 394036</p></bio><email xlink:type="simple">89805520393onk@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования Воронежский государственный медицинский университет имени Н. Н. Бурденко Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Education N. N. Burdenko Voronezh State Medical University of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>03</day><month>01</month><year>2023</year></pub-date><volume>0</volume><issue>12</issue><fpage>74</fpage><lpage>78</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зуйкова А.А., Бугримов Д.Ю., Красноруцкая О.Н., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Зуйкова А.А., Бугримов Д.Ю., Красноруцкая О.Н.</copyright-holder><copyright-holder xml:lang="en">Zuikova A.A., Bugrimov D.Y., Krasnorutskaya O.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.lvrach.ru/jour/article/view/1008">https://journal.lvrach.ru/jour/article/view/1008</self-uri><abstract><p>Последствия перенесенной новой коронавирусной инфекции стали не менее актуальными, чем симптоматика острого течения данного инфекционного заболевания. Разнообразные физические, когнитивные и нейропсихические симптомы, возникшие вследствие перенесенной инфекции COVID-19, формируют клиническую картину постковидного синдрома, проявляющегося длительными функциональными ограничениями, которые негативно сказываются на качестве жизни реконвалесцентов. Практический опыт восстановительного лечения пациентов с постковидным синдромом показал, что базовым условием успешного оказания помощи является мультидисциплинарный подход: комплекс процедур – дозированная и адекватно подобранная лечебная физкультура, дыхательная гимнастика с применением респираторных тренажеров, массаж, психотерапия, физиотерапия (включая ингаляции), электро- и магнитотерапия, вибротерапия, гипербарическая оксигенация, рефлексотерапия, а также нутритивная поддержка. Нутритивная поддержка пациентов с постковидным синдромом рассматривается как один из компонентов комплексного восстановительного лечения, направленного на коррекцию системной вирусной воспалительной реакции и метаболического статуса у больных COVID-19. В статье проанализирован практический опыт применения программ восстановительного лечения пациентов с COVID-19 в условиях амбулаторно-поликлинических медицинских организаций с включением в обязательную часть нутритивной поддержки, основанной на витамино- и ДНК-содержащих биологических активных добавках. Результаты исследования доказывают тот факт, что адекватная коррекция физического и нейропсихического статусов в сочетании с полноценной нутритивной поддержкой пациентов с различной степенью выраженности течения постковидного синдрома является неотъемлемой частью восстановительного лечения. Комплексное восстановительное лечение пациентов с COVID-19, основанное на индивидуальном подборе не только физических и физиотерапевтических схем лечения, но и нутритивной поддержке, позволит избежать многих отрицательных последствий патологии.</p></abstract><trans-abstract xml:lang="en"><p>The consequences of a new coronavirus infection have become no less relevant than the symptoms of an acute course of an infectious disease. A variety of physical, cognitive, and neuropsychic symptoms that arose as a result of the transferred COVID-19 form the clinical picture of the post-COVID syndrome, which is manifested by long-term functional limitations that negatively affect the quality of life of patients. Practical experience in the rehabilitation treatment of patients with post-COVID syndrome has shown that the basic condition for successful patient care is a multidisciplinary approach: a set of procedures – dosed and adequately selected physiotherapy exercises, breathing exercises using respiratory simulators, massage, psychotherapy, physiotherapy (including inhalations), electro – and magnetotherapy, vibration therapy, hyperbaric oxygen therapy, reflexology, as well as nutritional support. Nutritional support for patients with post-COVID syndrome is considered as one of the components of complex rehabilitation treatment aimed at correcting the systemic viral inflammatory response and metabolic status in patients with COVID-19. The article analyzes the practical experience of using rehabilitation treatment programs for patients with COVID-19 in outpatient medical organizations with inclusion in the mandatory part of nutritional support based on vitamin and DNA-containing biologically active supplements. The results of the study prove the fact that adequate correction of physical and neuropsychic status in combination with full nutritional support for patients with varying degrees of severity of post-COVID syndrome is an integral part of rehabilitation treatment. Comprehensive rehabilitation treatment of patients with COVID-19, based on the individual selection of not only physical and physiotherapeutic treatment regimens, but also nutritional support, will help to avoid many of the negative consequences of the pathology.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>восстановительное лечение</kwd><kwd>постковидный синдром</kwd><kwd>нутритивная поддержка</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rehabilitation treatment</kwd><kwd>post-COVID syndrome</kwd><kwd>nutritional support</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization. COVID-19 weekly epidemiological update. 9 February 2021.</mixed-citation><mixed-citation xml:lang="en">World Health Organization. COVID-19 weekly epidemiological update. 9 February 2021.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">De Biase S., Cook L., Skelton D. A., Witham M., ten Hove R. The COVID-19 rehabilitation pandemic // Age Ageing. 2020.</mixed-citation><mixed-citation xml:lang="en">De Biase S., Cook L., Skelton D. A., Witham M., ten Hove R. The COVID-19 rehabilitation pandemic // Age Ageing. 2020.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Bartlo P., Bauer N. Pulmonary Rehabilitation Post-Acute Care for Covid-19 (PACER). Available at: https://youtu.be/XjY_7O3Qpd8_ accessed 11.05.2020.</mixed-citation><mixed-citation xml:lang="en">Bartlo P., Bauer N. Pulmonary Rehabilitation Post-Acute Care for Covid-19 (PACER). Available at: https://youtu.be/XjY_7O3Qpd8_ accessed 11.05.2020.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Klok F. A., Boon G. J. A. M., Barco S., et al. The Post-COVID-19 Functional Status scale: a tool to measure functional status over time after COVID-19 // Eur Respir J. 2020; 56: 2001494 [https://doi.org/10.1183/13993003.01494-2020].</mixed-citation><mixed-citation xml:lang="en">Klok F. A., Boon G. J. A. M., Barco S., et al. The Post-COVID-19 Functional Status scale: a tool to measure functional status over time after COVID-19 // Eur Respir J. 2020; 56: 2001494 https://doi.org/10.1183/13993003.01494-2020.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Steardo L., Steardo L. Jr., Zorec R., et al. Neuroinfection may contribute to pathophysiology and clinical manifestations of COVID-19 // Acta Physiol. 2020; 229: e13473. DOI: 10.1111/apha.13473.</mixed-citation><mixed-citation xml:lang="en">Steardo L., Steardo L. Jr., Zorec R., et al. Neuroinfection may contribute to pathophysiology and clinical manifestations of COVID-19 // Acta Physiol. 2020; 229: e13473. DOI: 10.1111/apha.13473.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Carfì A., Bernabei R., Landi F. Persistent symptoms in patients after acute COVID-19 // JAMA. 2020; 324 (6): 603-605.</mixed-citation><mixed-citation xml:lang="en">Carfì A., Bernabei R., Landi F. Persistent symptoms in patients after acute COVID-19 // JAMA. 2020; 324 (6): 603-605.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">WHO Media Center 2021: Epidemiological and Operational updates. WHO reference number: WHO/2019-nCoV/clinical/2020.5.</mixed-citation><mixed-citation xml:lang="en">WHO Media Center 2021: Epidemiological and Operational updates. WHO reference number: WHO/2019-nCoV/clinical/2020.5.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Pietrobelli A., Pecoraro L., Ferruzzi A., et al. Effects of COVID-19 lockdown on lifestyle behaviors in children with obesity living in Verona, Italy: a longitudinal study // Obesity. 2020; 28: 1382-1385. [https://doi.org/10.1002/oby.22861].</mixed-citation><mixed-citation xml:lang="en">Pietrobelli A., Pecoraro L., Ferruzzi A., et al. Effects of COVID-19 lockdown on lifestyle behaviors in children with obesity living in Verona, Italy: a longitudinal study // Obesity. 2020; 28: 1382-1385. https://doi.org/10.1002/oby.22861.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19). Временные методические рекомендации. Версия 9. 26.10.2020. МЗ РФ. 236 с.</mixed-citation><mixed-citation xml:lang="en">Prevention, diagnosis and treatment of a new coronavirus infection (COVID-19) / Temporary guidelines // Versiya 9. (26.10.2020). MZ RF. P. 236.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Тутельян В. А., Никитюк Д. Б., Бурляева Е. А., Хотимченко С. А., Батурин А. К., Стародубова А. В. и др. COVID-19: новые вызовы для медицинской науки и практического здравоохранения // Вопросы питания. 2020; 3 (89): 6-13. DOI: https://doi.org/10.24411/0042-8833-2020-10024.</mixed-citation><mixed-citation xml:lang="en">Tutel'yan V. A., Nikityuk D. B., Burlyayeva Ye. A., Khotimchenko S .A., Baturin A. K., Starodubova A. V. i dr. COVID-19: new challenges for medical science and practical healthcare // Voprosy pitaniya. 2020. T. 89, № 3. S. 6-13. DOI: https://doi.org/10.24411/0042-8833-2020-10024.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Fernández-Quintela A., Milton-Laskibar I., Trepiana J., Gómez-Zorita S., Kajarabille N., Léniz A., et al. Key aspects in nutritional management of COVID-19 patients // J. Clin. Med. 2020; 8 (9). Article ID 2589. DOI: https://doi.org/10.3390/jcm9082589.</mixed-citation><mixed-citation xml:lang="en">Fernández-Quintela A., Milton-Laskibar I., Trepiana J., Gómez-Zorita S., Kajarabille N., Léniz A., et al. Key aspects in nutritional management of COVID-19 patients // J. Clin. Med. 2020; 8 (9). Article ID 2589. DOI: https://doi.org/10.3390/jcm9082589.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Beigmohammadi M. T., Bitarafan S., Hoseindokht A., et al. Impact of vitamins A, B, C, D, and E supplementation on improvement and mortality rate in ICU patients with coronavirus-19: a structured summary of a study protocol for a randomized controlled trial // Trials. 2020; 21: 614. DOI: https://doi.org/10.1186/s13063-020-04547-0.</mixed-citation><mixed-citation xml:lang="en">Beigmohammadi M. T., Bitarafan S., Hoseindokht A., et al. Impact of vitamins A, B, C, D, and E supplementation on improvement and mortality rate in ICU patients with coronavirus-19: a structured summary of a study protocol for a randomized controlled trial // Trials. 2020; 21: 614. DOI: https://doi.org/10.1186/s13063-020-04547-0.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Aman F., Masood S. How Nutrition can help to fight against COVID-19 pandemic // Pak. J. Med. Sci. 2020; 36: S121-S123. DOI: https://doi.org/10.12669/pjms.36.COVID19-S4.2776.</mixed-citation><mixed-citation xml:lang="en">Aman F., Masood S. How Nutrition can help to fight against COVID-19 pandemic // Pak. J. Med. Sci. 2020; 36: S121-S123. DOI: https://doi.org/10.12669/pjms.36.COVID19-S4.2776.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Shakoor H., Feehan J., Al Dhaheri S. A., Ali I. H., Platat C., Ismail C. L., et al. Immune boosting role of vitamins D, C, E, zinc, selenium and omega-3 fatty acids: could they help against COVID-19? // Maturitas. 2021; 143: 1-9. DOI: https://doi.org/10.1016/j.maturitas.2020.08.003.</mixed-citation><mixed-citation xml:lang="en">Shakoor H., Feehan J., Al Dhaheri S. A., Ali I. H., Platat C., Ismail C. L., et al. Immune boosting role of vitamins D, C, E, zinc, selenium and omega-3 fatty acids: could they help against COVID-19? // Maturitas. 2021; 143: 1-9. DOI: https://doi.org/10.1016/j.maturitas.2020.08.003.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Зуйкова А. А., Бугримов Д. Ю., Красноруцкая О. Н. с соавт. Практический опыт применения программ восстановительного лечения пациентов после COVID-19 в условиях амбулаторно-поликлинических медицинских организаций // Лечащий Врач. 2020; 12: 54-61.</mixed-citation><mixed-citation xml:lang="en">Zuykova A. A. Practical experience in the application of rehabilitation treatment programs for patients after COVID-19 in outpatient medical organizations / A. A. Zuykova, D. Yu. Bugrimov, O. N. Krasnorutskaya s soavt. // The Lechaschi Vrach Journal, 2020. № 12. S. 54-61.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин А. Г., Аметов А. С., Арутюнов Г. П., Драпкина О. М., Мартынов М. Ю., Мишланов В. Ю., Мосолов С. Н., Потекаев Н. Н., Солдатов Д. Г. Вопросник для первичной самооценки здоровья пациентов, перенесших новую коронавирусную инфекцию: Рекомендации Междисциплинарного совета экспертов по проведению скрининга симптомов постковидного периода при углубленной диспансеризации // Пульмонология. 2021; 31 (5): 599-612. DOI: 10.18093/0869-0189-2021-31-5-599-612.</mixed-citation><mixed-citation xml:lang="en">Chuchalin A. G., Ametov A. S., Arutyunov G. P., Drapkina O. M., Martynov M. Yu., Mishlanov V. Yu., Mosolov S. N., Potekayev N. N., Soldatov D. G. Questionnaire for the initial self-assessment of the health of patients with a new coronavirus infection: recommendations of the Interdisciplinary Expert Council for screening for symptoms of post-COVID period during in-depth medical examination. // Pul'monologiya. 2021; 31 (5): 599-612. DOI: 10.18093/0869-0189-2021-31-5-599-612.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Stefano B., Bruno B., Ilaria P. Low physical functioning and impaired performance of activities of daily life in COVID-19 patients who survived hospitalization // Spruit European Respiratory Journal. 2020; 56: 2002096. DOI: 10.1183/13993003.02096-2020/.</mixed-citation><mixed-citation xml:lang="en">Stefano B., Bruno B., Ilaria P. Low physical functioning and impaired performance of activities of daily life in COVID-19 patients who survived hospitalization // Spruit European Respiratory Journal. 2020; 56: 2002096. DOI: 10.1183/13993003.02096-2020/.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Bohannon R. W., Crouch R. 1-Minute sit-to-stand test: systematic review of procedures, performance, and clinimetric properties // J Cardiopulm Rehabil Prev. 2019; 39: 2-8. DOI: 10.1097/HCR.0000000000000336.</mixed-citation><mixed-citation xml:lang="en">Bohannon R. W., Crouch R. 1-Minute sit-to-stand test: systematic review of procedures, performance, and clinimetric properties // J Cardiopulm Rehabil Prev. 2019; 39: 2-8. DOI: 10.1097/HCR.0000000000000336.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Halpin S. J., McIvor C., Whyatt G. Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation // J. Med. Virol. 2021; 93: 1013-1022. https://doi.org/10.1002/jmv.26368.</mixed-citation><mixed-citation xml:lang="en">Halpin S. J., McIvor C., Whyatt G. Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation // J. Med. Virol. 2021; 93: 1013-1022. https://doi.org/10.1002/jmv.26368.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Филатов О. Ю., Назаров В. А. Образраспознающие рецепторы врожденного иммунитета и их роль в иммунотерапии (обзор) // Патогенез. 2020; 4 (18): 4-15.</mixed-citation><mixed-citation xml:lang="en">Filatov O. Yu. Pattern recognition receptors of innate immunity and their role in immunotherapy (review) / O. Yu. Filatov, V. A. Nazarov // Patogenez, T. 18, №4, 2020. P. 4-15.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
